Martin Tolstrup

Department of Clinical Medicine, Aarhus University

Affiliated withAarhus University Aarhus University Hospital

Research Area

Biography

Martin Tolstrup has not added Biography.
If you are Martin Tolstrup and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2020

Other Publications

Article	Year
Short-Course Toll-Like Receptor 9 Agonist Treatment Impacts Innate Immunity and Plasma Viremia in Individuals With Human Immunodeficiency Virus Infection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 28329286	2017
Full fusion competence rescue of the enfuvirtide resistant HIV-1 gp41 genotype (43D) by a prevalent polymorphism (137K). AIDS (London, England)\| PubMed ID: 17301572	2007
Entecavir therapy induces de novo HIV reverse-transcriptase M184V mutation in an antiretroviral therapy-naive patient. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 18419429	2008
Population-based study of diagnostic assays for Borrelia infection: comparison of purified flagella antigen assay (Ideia, Dako Cytomation) and recombinant antigen assay (Liaison, DiaSorin). BMC clinical pathology\| PubMed ID: 18423001	2008
Transmission of HIV-1 drug-resistant variants: prevalence and effect on treatment outcome. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 20085464	2010
Tenofovir selectively regulates production of inflammatory cytokines and shifts the IL-12/IL-10 balance in human primary cells. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 21471820	2011
Endotoxemia is associated with altered innate and adaptive immune responses in untreated HIV-1 infected individuals. PloS one\| PubMed ID: 21731690	2011
Induction of humoral and cellular immune responses against the HIV-1 envelope protein using γ-retroviral virus-like particles. Virology journal\| PubMed ID: 21806819	2011
Evaluation of cardiovascular biomarkers in HIV-infected patients switching to abacavir or tenofovir based therapy. BMC infectious diseases\| PubMed ID: 21970555	2011
Timing of Toll-like receptor 9 agonist administration in pneumococcal vaccination impacts both humoral and cellular immune responses as well as nasopharyngeal colonization in mice. Infection and immunity\| PubMed ID: 22371375	2012
Comparison of bone and renal effects in HIV-infected adults switching to abacavir or tenofovir based therapy in a randomized trial. PloS one\| PubMed ID: 22479327	2012
Construction of a gammaretrovirus with a novel tropism and wild-type replication kinetics capable of using human APJ as entry receptor. Journal of virology\| PubMed ID: 22811542	2012
TLR9-adjuvanted pneumococcal conjugate vaccine induces antibody-independent memory responses in HIV-infected adults. Human vaccines & immunotherapeutics\| PubMed ID: 22854665	2012
The impact of B-cell perturbations on pneumococcal conjugate vaccine response in HIV-infected adults. PloS one\| PubMed ID: 22860110	2012
Antiviral and immunological effects of tenofovir microbicide in vaginal herpes simplex virus 2 infection. AIDS research and human retroviruses\| PubMed ID: 22867119	2012
Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation. Human vaccines & immunotherapeutics\| PubMed ID: 23370291	2013
Eliminating the latent HIV reservoir by reactivation strategies: advancing to clinical trials. Human vaccines & immunotherapeutics\| PubMed ID: 23563519	2013
Administration of a Toll-like receptor 9 agonist decreases the proviral reservoir in virologically suppressed HIV-infected patients. PloS one\| PubMed ID: 23637967	2013
Anti-inflammatory effect of a retrovirus-derived immunosuppressive peptide in mouse models. BMC immunology\| PubMed ID: 24245569	2013
Comparison of the immunogenicity and reactogenicity of Cervarix and Gardasil human papillomavirus vaccines in HIV-infected adults: a randomized, double-blind clinical trial. The Journal of infectious diseases\| PubMed ID: 24273179	2014
Editorial commentary: Reversing latency in HIV-infected patients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 24336824	2014
T cells detect intracellular DNA but fail to induce type I IFN responses: implications for restriction of HIV replication. PloS one\| PubMed ID: 24404168	2014
Comparison of the immunogenicity of Cervarix® and Gardasil® human papillomavirus vaccines for oncogenic non-vaccine serotypes HPV-31, HPV-33, and HPV-45 in HIV-infected adults. Human vaccines & immunotherapeutics\| PubMed ID: 24553190	2014
Polymers fight HIV: potent (pro)drugs identified through parallel automated synthesis. Advanced healthcare materials\| PubMed ID: 24811313	2015
Highly active macromolecular prodrugs inhibit expression of the hepatitis C virus genome in the host cells. Advanced healthcare materials\| PubMed ID: 25132665	2015
Vaccination against oncogenic human papillomavirus infection in HIV-infected populations: review of current status and future perspectives. Sexual health\| PubMed ID: 25218800	2014
Disulfide reshuffling triggers the release of a thiol-free anti-HIV agent to make up fast-acting, potent macromolecular prodrugs. Chemical communications (Cambridge, England)\| PubMed ID: 25285337	2014
The histone deacetylase inhibitor panobinostat lowers biomarkers of cardiovascular risk and inflammation in HIV patients. AIDS (London, England)\| PubMed ID: 25870990	2015
Interleukin-37 Expression Is Increased in Chronic HIV-1-Infected Individuals and Is Associated with Inflammation and the Size of the Total Viral Reservoir. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 25879630	2015
High level of HIV-1 drug resistance among patients with HIV-1 and HIV-1/2 dual infections in Guinea-Bissau. Virology journal\| PubMed ID: 25889017	2015
Histone deacetylase inhibitor romidepsin inhibits de novo HIV-1 infections. Antimicrobial agents and chemotherapy\| PubMed ID: 25896701	2015
Activation of latent human immunodeficiency virus by the histone deacetylase inhibitor panobinostat: a pilot study to assess effects on the central nervous system. Open forum infectious diseases\| PubMed ID: 26034779	2015
HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days--Implications for HIV Remission. PLoS pathogens\| PubMed ID: 26133551	2015
Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat. Journal of virology\| PubMed ID: 26223643	2015
The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo. PLoS pathogens\| PubMed ID: 26379282	2015
Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial. The lancet. HIV\| PubMed ID: 26423811	2014
HIV-1 transcriptional activity during frequent longitudinal sampling in aviremic patients on antiretroviral therapy. AIDS (London, England)\| PubMed ID: 26595541	2016
Reversal of Latency as Part of a Cure for HIV-1. Trends in microbiology\| PubMed ID: 26690612	2016
Administration of Panobinostat Is Associated with Increased IL-17A mRNA in the Intestinal Epithelium of HIV-1 Patients. Mediators of inflammation\| PubMed ID: 26696749	2015
Polyanionic Macromolecular Prodrugs of Ribavirin: Antiviral Agents with a Broad Spectrum of Activity. Advanced healthcare materials\| PubMed ID: 26789641	2016
ART influences HIV persistence in the female reproductive tract and cervicovaginal secretions. The Journal of clinical investigation\| PubMed ID: 26854925	2016
Using animal models to overcome temporal, spatial and combinatorial challenges in HIV persistence research. Journal of translational medicine\| PubMed ID: 26861779	2016
A Novel Toll-Like Receptor 9 Agonist, MGN1703, Enhances HIV-1 Transcription and NK Cell-Mediated Inhibition of HIV-1-Infected Autologous CD4+ T Cells. Journal of virology\| PubMed ID: 26889036	2016
Human Papillomavirus neutralizing and cross-reactive antibodies induced in HIV-positive subjects after vaccination with quadrivalent and bivalent HPV vaccines. Vaccine\| PubMed ID: 26896686	2016
The potential role for romidepsin as a component in early HIV-1 curative efforts. Expert review of anti-infective therapy\| PubMed ID: 26953620	2016
New insights on the phenotype of HIV reservoirs. AIDS (London, England)\| PubMed ID: 27243776	2016
Triple Activity of Lamivudine Releasing Sulfonated Polymers against HIV-1. Molecular pharmaceutics\| PubMed ID: 27244595	2016
International AIDS Society global scientific strategy: towards an HIV cure 2016. Nature medicine\| PubMed ID: 27400264	2016
Immune checkpoints and the HIV-1 reservoir: proceed with caution. Journal of virus eradication\| PubMed ID: 27482460	2016
Modeling of Experimental Data Supports HIV Reactivation from Latency after Treatment Interruption on Average Once Every 5-8 Days. PLoS pathogens\| PubMed ID: 27560972	2016
Broad activation of latent HIV-1 in vivo. Nature communications\| PubMed ID: 27605062	2016
Combined effect of Vacc-4x, recombinant human granulocyte macrophage colony-stimulating factor vaccination, and romidepsin on the HIV-1 reservoir (REDUC): a single-arm, phase 1B/2A trial. The lancet. HIV\| PubMed ID: 27658863	2016
Macromolecular Prodrugs of Ribavirin: Structure-Function Correlation as Inhibitors of Influenza Infectivity. Molecular pharmaceutics\| PubMed ID: 28043136	2017
Romidepsin-induced HIV-1 viremia during effective antiretroviral therapy contains identical viral sequences with few deleterious mutations. AIDS (London, England)\| PubMed ID: 28272134	2017
Beyond antiretroviral therapy: early interventions to control HIV-1 infection. AIDS (London, England)\| PubMed ID: 28463884	2017
Anti-HIV-1 ADCC Antibodies following Latency Reversal and Treatment Interruption. Journal of virology\| PubMed ID: 28539449	2017
Macromolecular prodrugs of ribavirin: towards a treatment for co-infection with HIV and HCV. Chemical science\| PubMed ID: 28580095	2015
The TLR9 agonist MGN1703 triggers a potent type I interferon response in the sigmoid colon. Mucosal immunology\| PubMed ID: 28766555	2018
HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal. JCI insight\| PubMed ID: 28814661	2017
Macromolecular Antiviral Agents against Zika, Ebola, SARS, and Other Pathogenic Viruses. Advanced healthcare materials\| PubMed ID: 28945945	2017
Estimating Initial Viral Levels during Simian Immunodeficiency Virus/Human Immunodeficiency Virus Reactivation from Latency. Journal of virology\| PubMed ID: 29118123	2018
Cellular immunogenicity of human papillomavirus vaccines Cervarix and Gardasil in adults with HIV infection. Human vaccines & immunotherapeutics\| PubMed ID: 29172992	2018
Macromolecular prodrugs of ribavirin: Polymer backbone defines blood safety, drug release, and efficacy of anti-inflammatory effects. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 29432822	2018
Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and Limits Lipopolysaccharide-Induced Inflammato... mSphere\| PubMed ID: 29468194	2018
Levels of regulatory B cells do not predict serological responses to hepatitis B vaccine. Human vaccines & immunotherapeutics\| PubMed ID: 29474139	2018
Multiple Homozygous Variants in the STING-Encoding Gene in HIV Long-Term Nonprogressors. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 29632140	2018
Genetic characterization of the HIV-1 reservoir after Vacc-4x and romidepsin therapy in HIV-1-infected individuals. AIDS (London, England)\| PubMed ID: 29762162	2018
HIV anti-latency treatment mediated by macromolecular prodrugs of histone deacetylase inhibitor, panobinostat. Chemical science\| PubMed ID: 29997778	2016
Differences in antiretroviral regimens do not impact safety or level of latency reversal in persons receiving romidepsin. AIDS (London, England)\| PubMed ID: 30001247	2018
Whole Exome Sequencing of HIV-1 long-term non-progressors identifies rare variants in genes encoding innate immune sensors and signaling molecules. Scientific reports\| PubMed ID: 30323326	2018
Characterization of the HIV-1 transcription profile after romidepsin administration in ART-suppressed individuals. AIDS (London, England)\| PubMed ID: 30531314	2019
Non-covalent hitchhiking on endogenous carriers as a protraction mechanism for antiviral macromolecular prodrugs. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 30552954	2019
Characterization of Intact Proviruses in Blood and Lymph Node from HIV-Infected Individuals Undergoing Analytical Treatment Interruption. Journal of virology\| PubMed ID: 30700598	2019
In-vivo administration of histone deacetylase inhibitors does not impair natural killer cell function in HIV+ individuals. AIDS (London, England)\| PubMed ID: 30830886	2019
cAIMP administration in humanized mice induces a chimerization-level-dependent STING response. Immunology\| PubMed ID: 30919991	2019
Effects of 24-week Toll-like receptor 9 agonist treatment in HIV type 1+ individuals. AIDS (London, England)\| PubMed ID: 30932955	2019
Nucleic Acids as a Nature-Inspired Scaffold for Macromolecular Prodrugs of Nucleoside Analogues. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 30937274	2019
TLR9 agonist MGN1703 enhances B cell differentiation and function in lymph nodes. EBioMedicine\| PubMed ID: 31300344	2019
IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease. Nature immunology\| PubMed ID: 31427775	2019
Impacts of HIV Cure Interventions on Viral Reservoirs in Tissues. Frontiers in microbiology\| PubMed ID: 31497010	2019
Fimepinostat, a novel dual inhibitor of HDAC and PI3K, effectively reverses HIV-1 latency without T cell activation. Journal of virus eradication\| PubMed ID: 31700655	2019
Fimepinostat, a novel dual inhibitor of HDAC and PI3K, effectively reverses HIV-1 latency without T cell activation. Journal of virus eradication\| PubMed ID: 31700656	2019