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JoVE Journal
Immunology and Infection

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Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
 

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Article doi: 10.3791/60723
January 31st, 2020

Summary January 31st, 2020

We have developed a protocol for the generation and evaluation of a humanized and human immunodeficiency virus-infected NOG mouse model based on stem cell transplant, intravaginal human immunodeficiency virus exposure, and droplet digital PCR RNA quantification.

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