Michael Sendtner

Institute for Clinical Neurobiology, University of Wuerzburg

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 21	2011

Other Publications

Article	Year
Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? Human molecular genetics\| PubMed ID: 11773003	2002
Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult. The Journal of cell biology\| PubMed ID: 11807093	2002
Association of a null mutation in the CNTF gene with early onset of multiple sclerosis. Archives of neurology\| PubMed ID: 11890844	2002
Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene. American journal of human genetics\| PubMed ID: 11951178	2002
CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation. Nature medicine\| PubMed ID: 12042814	2002
Gene targeting of Gemin2 in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12091709	2002
The Gene for Ciliary Neurotrophic Factor (CNTF) Maps to Murine Chromosome 19 and its Expression is Not Affected in the Hereditary Motoneuron Disease 'Wobbler' of the Mouse. The European journal of neuroscience\| PubMed ID: 12106247	1991
Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches. Nature neuroscience\| PubMed ID: 12403983	2002
Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease. The Journal of cell biology\| PubMed ID: 12446740	2002
A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy. The Journal of cell biology\| PubMed ID: 12515823	2003
Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues. The Biochemical journal\| PubMed ID: 12521380	2003
Early onset of degenerative changes at nodes of Ranvier in alpha-motor axons of Cntf null (-/-) mutant mice. Glia\| PubMed ID: 12730954	2003
Endogenous ciliary neurotrophic factor protects GABAergic, but not cholinergic, septohippocampal neurons following fimbria-fornix transection. Brain pathology (Zurich, Switzerland)\| PubMed ID: 12946020	2003
Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneurons. The Journal of cell biology\| PubMed ID: 14623865	2003
Dynamic changes in C-Raf phosphorylation and 14-3-3 protein binding in response to growth factor stimulation: differential roles of 14-3-3 protein binding sites. The Journal of biological chemistry\| PubMed ID: 14688280	2004
Axonal defects in mouse models of motoneuron disease. Journal of neurobiology\| PubMed ID: 14704958	2004
The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E. The Journal of cell biology\| PubMed ID: 15051733	2004
The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes & development\| PubMed ID: 15107403	2004
Characterization of Ighmbp2 in motor neurons and implications for the pathomechanism in a mouse model of human spinal muscular atrophy with respiratory distress type 1 (SMARD1). Human molecular genetics\| PubMed ID: 15269181	2004
Truncated TrkB receptor-induced outgrowth of dendritic filopodia involves the p75 neurotrophin receptor. Journal of cell science\| PubMed ID: 15507485	2004
Optical assessment of motoneuron function in a "twenty-four-hour" acute spinal cord slice model from fetal rats. Journal of neuroscience methods\| PubMed ID: 15661313	2005
Glycinergic and GABAergic synaptic activity differentially regulate motoneuron survival and skeletal muscle innervation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15689563	2005
Triple knock-out of CNTF, LIF, and CT-1 defines cooperative and distinct roles of these neurotrophic factors for motoneuron maintenance and function. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15716414	2005
Motoneuron survival after C7 nerve root avulsion and replantation in the adult rabbit: effects of local ciliary neurotrophic factor and brain-derived neurotrophic factor application. Plastic and reconstructive surgery\| PubMed ID: 15923853	2005
Mechanisms of axonal degeneration in EAE--lessons from CNTF and MHC I knockout mice. Journal of the neurological sciences\| PubMed ID: 15949503	2005
Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells. Nature neuroscience\| PubMed ID: 16116448	2005
The role of neurotrophins in muscle under physiological and pathological conditions. Muscle & nerve\| PubMed ID: 16228973	2006
Evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1. Neuron\| PubMed ID: 16242406	2005
Damaging secretions: chromogranins team up with mutant SOD1. Nature neuroscience\| PubMed ID: 16378088	2006
Distinct and overlapping alterations in motor and sensory neurons in a mouse model of spinal muscular atrophy. Human molecular genetics\| PubMed ID: 16396995	2006
Loss of leukemia inhibitory factor receptor beta or cardiotrophin-1 causes similar deficits in preganglionic sympathetic neurons and adrenal medulla. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16467531	2006
Sox10 regulates ciliary neurotrophic factor gene expression in Schwann cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16684879	2006
High-efficiency gene transfer into cultured embryonic motoneurons using recombinant lentiviruses. Histochemistry and cell biology\| PubMed ID: 17102992	2007
Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. Developmental biology\| PubMed ID: 17150206	2007
Novel SOD1 N86K mutation is associated with a severe phenotype in familial ALS. Muscle & nerve\| PubMed ID: 17299743	2007
Large-scale pathways-based association study in amyotrophic lateral sclerosis. Brain : a journal of neurology\| PubMed ID: 17439985	2007
The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis. The Journal of biological chemistry\| PubMed ID: 17556369	2007
Differential modulation of neurite growth by the S- and the L-forms of bag1, a co-chaperone of Hsp70. Neuro-degenerative diseases\| PubMed ID: 17596720	2007
Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages. Development (Cambridge, England)\| PubMed ID: 17699610	2007
Defective Ca2+ channel clustering in axon terminals disturbs excitability in motoneurons in spinal muscular atrophy. The Journal of cell biology\| PubMed ID: 17923533	2007
Haploinsufficiency of c-Met in cd44-/- mice identifies a collaboration of CD44 and c-Met in vivo. Molecular and cellular biology\| PubMed ID: 17923692	2007
Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17940030	2007
Leukemia inhibitory factor deficiency modulates the immune response and limits autoimmune demyelination: a new role for neurotrophic cytokines in neuroinflammation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18250427	2008
Single-dose application of CNTF and BDNF improves remyelination of regenerating nerve fibers after C7 ventral root avulsion and replantation. Journal of neurotrauma\| PubMed ID: 18373486	2008
Spiral ganglion outgrowth and hearing development in p75-deficient mice. Audiology & neuro-otology\| PubMed ID: 18663291	2008
Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18923022	2008
Stem cells: Tailor-made diseased neurons. Nature\| PubMed ID: 19148087	2009
Drosophila RSK negatively regulates bouton number at the neuromuscular junction. Developmental neurobiology\| PubMed ID: 19160443	2009
A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. Human molecular genetics\| PubMed ID: 19193627	2009
P90 Ribosomal s6 kinase 2 negatively regulates axon growth in motoneurons. Molecular and cellular neurosciences\| PubMed ID: 19555761	2009
Valproic acid blocks excitability in SMA type I mouse motor neurons. Neurobiology of disease\| PubMed ID: 19733665	2009
Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell\| PubMed ID: 19766573	2009
Progressive postnatal motoneuron loss in mice lacking GDF-15. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19864576	2009
C-terminal FUS/TLS mutations in familial and sporadic ALS in Germany. Neurobiology of aging\| PubMed ID: 20018407	2011
Ciliary neurotrophic factor-induced sprouting preserves motor function in a mouse model of mild spinal muscular atrophy. Human molecular genetics\| PubMed ID: 20022887	2010
Isolation and enrichment of embryonic mouse motoneurons from the lumbar spinal cord of individual mouse embryos. Nature protocols\| PubMed ID: 20057379	2010
Neuromuscular defects and breathing disorders in a new mouse model of spinal muscular atrophy. Neurobiology of disease\| PubMed ID: 20085811	2010
Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20130183	2010
The heterogeneous nuclear ribonucleoprotein-R is necessary for axonal beta-actin mRNA translocation in spinal motor neurons. Human molecular genetics\| PubMed ID: 20167579	2010
Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis. BMC genomics\| PubMed ID: 20346106	2010
PTEN depletion rescues axonal growth defect and improves survival in SMN-deficient motor neurons. Human molecular genetics\| PubMed ID: 20525971	2010
Therapy development in spinal muscular atrophy. Nature neuroscience\| PubMed ID: 20581815	2010
Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis. Brain : a journal of neurology\| PubMed ID: 20826430	2010
Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. Brain : a journal of neurology\| PubMed ID: 20929960	2011
TDP-43: multiple targets, multiple disease mechanisms? Nature neuroscience\| PubMed ID: 21445063	2011
A new postal code for dendritic mRNA transport in neurons. EMBO reports\| PubMed ID: 21681203	2011
Regenerative medicine: Bespoke cells for the human brain. Nature\| PubMed ID: 21833079	2011
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron\| PubMed ID: 21944779	2011
Therapeutic effects of PEGylated insulin-like growth factor I in the pmn mouse model of motoneuron disease. Experimental neurology\| PubMed ID: 21963648	2011
Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis. Nature reviews. Neurology\| PubMed ID: 22051914	2011
Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts. Blood\| PubMed ID: 22058113	2012
Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes\| PubMed ID: 22124465	2012
Microtubule associated tumor suppressor 1 deficient mice develop spontaneous heart hypertrophy and SLE-like lymphoproliferative disease. International journal of oncology\| PubMed ID: 22200760	2012