Ron Weiss

Synthetic Biology Center, Massachusetts Institute of Technology

Affiliated withMassachusetts Institute of Technology

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 1	2023
Publication title Cited by 4	2020

Other Publications

Article	Year
Design and connection of robust genetic circuits. Methods in enzymology\| PubMed ID: 21601086	2011
Automatic compilation from high-level biologically-oriented programming language to genetic regulatory networks. PloS one\| PubMed ID: 21850228	2011
Understanding signaling dynamics through synthesis. Science signaling\| PubMed ID: 22510466	2012
Foundations for the design and implementation of synthetic genetic circuits. Nature reviews. Genetics\| PubMed ID: 22596318	2012
Modular design of artificial tissue homeostasis: robust control through synthetic cellular heterogeneity. PLoS computational biology\| PubMed ID: 22829755	2012
Formation and optogenetic control of engineered 3D skeletal muscle bioactuators. Lab on a chip\| PubMed ID: 22976544	2012
Genetically programmable pathogen sense and destroy. ACS synthetic biology\| PubMed ID: 23763381	2013
Rapid, modular and reliable construction of complex mammalian gene circuits. Nucleic acids research\| PubMed ID: 23847100	2013
Microbead-based biomimetic synthetic neighbors enhance survival and function of rat pancreatic β-cells. Scientific reports\| PubMed ID: 24091640	2013
Realizing the potential of synthetic biology. Nature reviews. Molecular cell biology\| PubMed ID: 24622617	2014
CRISPR transcriptional repression devices and layered circuits in mammalian cells. Nature methods\| PubMed ID: 24797424	2014
Systematic transfer of prokaryotic sensors and circuits to mammalian cells. ACS synthetic biology\| PubMed ID: 25360681	2014
Accurate predictions of genetic circuit behavior from part characterization and modular composition. ACS synthetic biology\| PubMed ID: 25369267	2015
A platform for rapid prototyping of synthetic gene networks in mammalian cells. Nucleic acids research\| PubMed ID: 25378321	2014
Rapid neurogenesis through transcriptional activation in human stem cells. Molecular systems biology\| PubMed ID: 25403753	2014
A load driver device for engineering modularity in biological networks. Nature biotechnology\| PubMed ID: 25419739	2014
Modular construction of mammalian gene circuits using TALE transcriptional repressors. Nature chemical biology\| PubMed ID: 25643171	2015
Highly efficient Cas9-mediated transcriptional programming. Nature methods\| PubMed ID: 25730490	2015
Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery. Nature biotechnology\| PubMed ID: 26237515	2015
Isocost Lines Describe the Cellular Economy of Genetic Circuits. Biophysical journal\| PubMed ID: 26244745	2015
Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes. Cell metabolism\| PubMed ID: 26244933	2015
SYNTHETIC BIOLOGY. Synthetic communities, the sum of parts. Science (New York, N.Y.)\| PubMed ID: 26315419	2015
N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 26342664	2015
Cas9 gRNA engineering for genome editing, activation and repression. Nature methods\| PubMed ID: 26344044	2015
Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6. Nature communications\| PubMed ID: 26732624	2016
Synthetic Morphogenesis. Cold Spring Harbor perspectives in biology\| PubMed ID: 27270296	2016
A novel Bxb1 integrase RMCE system for high fidelity site-specific integration of mAb expression cassette in CHO Cells. Biotechnology and bioengineering\| PubMed ID: 28186334	2017
Open-source, community-driven microfluidics with Metafluidics. Nature biotechnology\| PubMed ID: 28591125	2017
A Modular Approach to Building Complex Synthetic Circuits. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 28801911	2017
Programming gene and engineered-cell therapies with synthetic biology. Science (New York, N.Y.)\| PubMed ID: 29439214	2018
A multi-landing pad DNA integration platform for mammalian cell engineering. Nucleic acids research\| PubMed ID: 29617873	2018
Engineering modular intracellular protein sensor-actuator devices. Nature communications\| PubMed ID: 29760420	2018
Stochastic Turing patterns in a synthetic bacterial population. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 29891706	2018
A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity. Nature communications\| PubMed ID: 29934631	2018
Small-molecule-based regulation of RNA-delivered circuits in mammalian cells. Nature chemical biology\| PubMed ID: 30327560	2018
Engineering protein-protein devices for multilayered regulation of mRNA translation using orthogonal proteases in mammalian cells. Nature communications\| PubMed ID: 30349044	2018
Author Correction: A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity. Nature communications\| PubMed ID: 30389927	2018
Comparison of Integrases Identifies Bxb1-GA Mutant as the Most Efficient Site-Specific Integrase System in Mammalian Cells. ACS synthetic biology\| PubMed ID: 30609349	2019
Dissecting N-Glycosylation Dynamics in Chinese Hamster Ovary Cells Fed-batch Cultures using Time Course Omics Analyses. iScience\| PubMed ID: 30682623	2019
In vitro evolution of enhanced RNA replicons for immunotherapy. Scientific reports\| PubMed ID: 31061426	2019
Perspective: The promise of multi-cellular engineered living systems. APL bioengineering\| PubMed ID: 31069321	2018
Small-molecule control of antibody N-glycosylation in engineered mammalian cells. Nature chemical biology\| PubMed ID: 31110306	2019
A high-throughput screening and computation platform for identifying synthetic promoters with enhanced cell-state specificity (SPECS). Nature communications\| PubMed ID: 31253799	2019
A 'poly-transfection' method for rapid, one-pot characterization and optimization of genetic systems. Nucleic acids research\| PubMed ID: 31372658	2019
Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 31515132	2019
An Artificial Tissue Homeostasis Circuit Designed via Analog Circuit Techniques. IEEE transactions on biomedical circuits and systems\| PubMed ID: 30908238	2019
3D aggregation of cells in packed microgel media. Soft matter\| PubMed ID: 32589183	2020
Correction: 3D aggregation of cells in packed microgel media. Soft matter\| PubMed ID: 32639490	2020
Principles of synthetic biology: a MOOC for an emerging field. Synthetic biology (Oxford, England)\| PubMed ID: 32995535	2019
An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells. Nature communications\| PubMed ID: 33173034	2020
In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 33186690	2021
Rethinking organoid technology through bioengineering. Nature materials\| PubMed ID: 33199860	2021
TASBE Image Analytics: A Processing Pipeline for Quantifying Cell Organization from Fluorescent Microscopy. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 33340350	2021
Context-aware synthetic biology by controller design: Engineering the mammalian cell. Cell systems\| PubMed ID: 34139166	2021
An engineered protein-phosphorylation toggle network with implications for endogenous network discovery. Science (New York, N.Y.)\| PubMed ID: 34210851	2021
Quantitative characterization of recombinase-based digitizer circuits enables predictable amplification of biological signals. Communications biology\| PubMed ID: 34267310	2021
Multifunctional oncolytic nanoparticles deliver self-replicating IL-12 RNA to eliminate established tumors and prime systemic immunity. Nature cancer\| PubMed ID: 34447945	2020
Meeting Measurement Precision Requirements for Effective Engineering of Genetic Regulatory Networks. ACS synthetic biology\| PubMed ID: 35156365	2022
Principles for the design of multicellular engineered living systems. APL bioengineering\| PubMed ID: 35274072	2022
Robust and tunable signal processing in mammalian cells via engineered covalent modification cycles. Nature communications\| PubMed ID: 35361767	2022
PERSIST platform provides programmable RNA regulation using CRISPR endoRNases. Nature communications\| PubMed ID: 35562172	2022
Synthetic neuromorphic computing in living cells. Nature communications\| PubMed ID: 36153343	2022
A synthetic transcription platform for programmable gene expression in mammalian cells. Nature communications\| PubMed ID: 36257931	2022
The sound of silence: Transgene silencing in mammalian cell engineering. Cell systems\| PubMed ID: 36549273	2022
Synthetic genetic circuits to uncover and enforce the OCT4 trajectories of successful reprogramming of human fibroblasts. bioRxiv : the preprint server for biology\| PubMed ID: 36747813	2023
Cholesterol-Amino-Phosphate (CAP) Derived Lipid Nanoparticles for Delivery of Self-Amplifying RNA and Restoration of Spermatogenesis in Infertile Mice. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 36748274	2023