Yan Chai

CAS Key Laboratory of Pathogenic Microbiology and Immunology, Chinese Academy of Sciences

Affiliated withChinese Academy of Sciences

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2021

Other Publications

Article	Year
[Distribution of organochlorine pesticides in surface sediments from the middle and lower reaches of the Yellow River]. Huan jing ke xue= Huanjing kexue\| PubMed ID: 17674745	2007
Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 27511732	2016
Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy. Cell research\| PubMed ID: 27573173	2017
Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 27903740	2017
An unexpected N-terminal loop in PD-1 dominates binding by nivolumab. Nature communications\| PubMed ID: 28165004	2017
The crystal structure of Zika virus NS5 reveals conserved drug targets. The EMBO journal\| PubMed ID: 28254839	2017
Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab. Protein & cell\| PubMed ID: 28488247	2018
Alternate binding modes of anti-CRISPR viral suppressors AcrF1/2 to Csy surveillance complex revealed by cryo-EM structures. Cell research\| PubMed ID: 28574055	2017
Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28827346	2017
Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies. Oncotarget\| PubMed ID: 28978021	2017
The Postfusion Structure of the Heartland Virus Gc Glycoprotein Supports Taxonomic Separation of the Bunyaviral Families Phenuiviridae and Hantaviridae. Journal of virology\| PubMed ID: 29070692	2018
Two classes of protective antibodies against Pseudorabies virus variant glycoprotein B: Implications for vaccine design. PLoS pathogens\| PubMed ID: 29261802	2017
Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses. mBio\| PubMed ID: 30087171	2018
Structural and functional insights into MCR-2 mediated colistin resistance. Science China. Life sciences\| PubMed ID: 30194678	2018
An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 30341185	2018
Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab. Cell reports\| PubMed ID: 30355497	2018
Glycosylation-independent binding of monoclonal antibody toripalimab to FG loop of PD-1 for tumor immune checkpoint therapy. mAbs\| PubMed ID: 30892132	2019
Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus. Nature microbiology\| PubMed ID: 30936489	2019
The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy. iScience\| PubMed ID: 30952089	2019
Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein. Cell\| PubMed ID: 31080063	2019
Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development. Cancer immunology research\| PubMed ID: 31213474	2019
Divergent Peptide Presentations of HLA-A30 Alleles Revealed by Structures With Pathogen Peptides. Frontiers in immunology\| PubMed ID: 31396224	2019
Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. PLoS biology\| PubMed ID: 31498797	2019
Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target. mBio\| PubMed ID: 31662460	2019
The identification of a CD47-blocking "hotspot" and design of a CD47/PD-L1 dual-specific antibody with limited hemagglutination. Signal transduction and targeted therapy\| PubMed ID: 32296041	2020
The structural basis of African swine fever virus pA104R binding to DNA and its inhibition by stilbene derivatives. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32358196	2020
Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32690697	2020
Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus. mBio\| PubMed ID: 33024040	2020
N-glycosylation of PD-1 promotes binding of camrelizumab. EMBO reports\| PubMed ID: 33063473	2020
Molecular basis of EphA2 recognition by gHgL from gammaherpesviruses. Nature communications\| PubMed ID: 33235207	2020
A broadly protective antibody that targets the flavivirus NS1 protein. Science (New York, N.Y.)\| PubMed ID: 33414219	2021