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JoVE Journal
Immunology and Infection

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Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin
 

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin

Article doi: 10.3791/61462
March 10th, 2021

Summary March 10th, 2021

The protocol describes experimental methods to obtain stable major histocompatibility complex (MHC) class I through potential β2-microglobulin (β2m) substitutions from different species. The structural comparison of MHC I stabilized by homologous and heterologous β2m were investigated.

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