Jianxin Lyu

School of Laboratory Medicine and Life Sciences, Wenzhou Medical University

Affiliated withWenzhou Medical University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2021

Other Publications

Article	Year
[Establishment and application of quantitative detection for heteroplasmic mtDNA mutation 3243A→G]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics\| PubMed ID: 25119906	2014
[NK4 growth inhibition of human Raji lymphoma xenografts by competitive interrupting HGF/Met signal pathway]. Zhonghua bing li xue za zhi = Chinese journal of pathology\| PubMed ID: 25346127	2014
[Investigation of a family with Kennedy disease by genetic analysis]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics\| PubMed ID: 25449081	2014
Secreted and O-GlcNAcylated MIF binds to the human EGF receptor and inhibits its activation. Nature cell biology\| PubMed ID: 26280537	2015
An investigation on the population structure of mixed infections of Mycobacterium tuberculosis in Inner Mongolia, China. Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 26542224	2015
[Effect of mitochondrial DNA 5178 C/A polymorphism on risks for type 2 diabetes mellitus and its complications]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics\| PubMed ID: 26663065	2015
Mitochondrial common deletion is elevated in blood of breast cancer patients mediated by oxidative stress. Mitochondrion\| PubMed ID: 26678158	2016
Mitochondrial DNA haplogroups modify the risk of osteoarthritis by altering mitochondrial function and intracellular mitochondrial signals. Biochimica et biophysica acta\| PubMed ID: 26705675	2016
EGFR phosphorylates FAM129B to promote Ras activation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26721396	2016
His-87 ligand in mitoNEET is crucial for the transfer of iron sulfur clusters from mitochondria to cytosolic aconitase. Biochemical and biophysical research communications\| PubMed ID: 26778000	2016
Optimization of a NH4PF6-enhanced, non-organic solvent, dual microextraction method for determination of phthalate metabolites in urine by high performance liquid chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 26852090	2016
Metformin inhibits prostate cancer cell proliferation, migration, and tumor growth through upregulation of PEDF expression. Cancer biology & therapy\| PubMed ID: 26987032	2016
Carnosine decreased neuronal cell death through targeting glutamate system and astrocyte mitochondrial bioenergetics in cultured neuron/astrocyte exposed to OGD/recovery. Brain research bulletin\| PubMed ID: 27040711	2016
Telomerase reverse transcriptase promoter mutations in hepatitis B virus-associated hepatocellular carcinoma. Oncotarget\| PubMed ID: 27056898	2016
A Novel Technique to Detect EGFR Mutations in Lung Cancer. International journal of molecular sciences\| PubMed ID: 27223277	2016
Decreased IL-17 during treatment of sputum smear-positive pulmonary tuberculosis due to increased regulatory T cells and IL-10. Journal of translational medicine\| PubMed ID: 27311307	2016
Cell Type-Specific Modulation of Respiratory Chain Supercomplex Organization. International journal of molecular sciences\| PubMed ID: 27338358	2016
Methylglyoxal suppresses human colon cancer cell lines and tumor growth in a mouse model by impairing glycolytic metabolism of cancer cells associated with down-regulation of c-Myc expressio... Cancer biology & therapy\| PubMed ID: 27455418	2016
Upregulation of SQSTM1/p62 contributes to nickel-induced malignant transformation of human bronchial epithelial cells. Autophagy\| PubMed ID: 27467530	2016
MicroRNA-21 promotes proliferation, migration, and invasion of colorectal cancer, and tumor growth associated with down-regulation of sec23a expression. BMC cancer\| PubMed ID: 27495250	2016
Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy. Cell research\| PubMed ID: 27573173	2017
Design and Construction of a Multi-Organ Microfluidic Chip Mimicking the in vivo Microenvironment of Lung Cancer Metastasis. ACS applied materials & interfaces\| PubMed ID: 27606718	2016
Predictive value of serum bradykinin and desArg-bradykinin levels for chemotherapeutic responses in active tuberculosis patients: A retrospective case series. Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 27720377	2016
Novel mutation of ND4 gene identified by targeted next-generation sequencing in patient with Leigh syndrome. Journal of human genetics\| PubMed ID: 27761019	2016
Carnosine Inhibits the Proliferation of Human Cervical Gland Carcinoma Cells Through Inhibiting Both Mitochondrial Bioenergetics and Glycolysis Pathways and Retarding Cell Cycle Progression. Integrative cancer therapies\| PubMed ID: 28008780	2018
Carnosine modulates glutamine synthetase expression in senescent astrocytes exposed to oxygen-glucose deprivation/recovery. Brain research bulletin\| PubMed ID: 28115195	2017
Accurate quantitation of circulating cell-free mitochondrial DNA in plasma by droplet digital PCR. Analytical and bioanalytical chemistry\| PubMed ID: 28154880	2017
Blockage of Glyoxalase I Inhibits Colorectal Tumorigenesis and Tumor Growth via Upregulation of STAT1, p53, and Bax and Downregulation of c-Myc and Bcl-2. International journal of molecular sciences\| PubMed ID: 28282916	2017
MiR-93 Promotes Tumorigenesis and Metastasis of Non-Small Cell Lung Cancer Cells by Activating the PI3K/Akt Pathway via Inhibition of //. Journal of Cancer\| PubMed ID: 28382150	2017
[Analysis of genome-wide copy number variations among fetuses with abnormalities detected by prenatal ultrasouography]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics\| PubMed ID: 28397213	2017
Plasma-derived exosomes contribute to inflammation via the TLR9-NF-κB pathway in chronic heart failure patients. Molecular immunology\| PubMed ID: 28433888	2017
Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy. Molecular cell\| PubMed ID: 28552616	2017
Anaerobic Copper Toxicity and Iron-Sulfur Cluster Biogenesis in Escherichia coli. Applied and environmental microbiology\| PubMed ID: 28576762	2017
MicroRNA-4530 promotes angiogenesis by targeting VASH1 in breast carcinoma cells. Oncology letters\| PubMed ID: 28693142	2017
A complex association between DNA methylation and gene expression in human placenta at first and third trimesters. PloS one\| PubMed ID: 28704530	2017
Metformin Inhibits Tumorigenesis and Tumor Growth of Breast Cancer Cells by Upregulating miR-200c but Downregulating AKT2 Expression. Journal of Cancer\| PubMed ID: 28819383	2017
Synergistic inhibition of colon cancer growth by the combination of methylglyoxal and silencing of glyoxalase I mediated by the STAT1 pathway. Oncotarget\| PubMed ID: 28903386	2017
The interaction between mitochondria and oncoviruses. Biochimica et biophysica acta. Molecular basis of disease\| PubMed ID: 28962899	2018
Generation and Bioenergetic Profiles of Cybrids with East Asian mtDNA Haplogroups. Oxidative medicine and cellular longevity\| PubMed ID: 29093766	2017
KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase. Nature\| PubMed ID: 29211711	2017
Breast cancer-associated mitochondrial DNA haplogroup promotes neoplastic growth via ROS-mediated AKT activation. International journal of cancer\| PubMed ID: 29226320	2018
Serum miR-486-5p as a diagnostic marker in cervical cancer: with investigation of potential mechanisms. BMC cancer\| PubMed ID: 29316891	2018
Oncocytic tumors are marked by enhanced mitochondrial content and mtDNA mutations of complex I in Chinese patients. Mitochondrion\| PubMed ID: 29386142	2019
Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth. Cell death & disease\| PubMed ID: 29415987	2018
Combination of in situ metathesis reaction with a novel "magnetic effervescent tablet-assisted ionic liquid dispersive microextraction" for the determination of endogenous steroids in human ... Analytical and bioanalytical chemistry\| PubMed ID: 29532194	2018
Establishment of a nine-gene prognostic model for predicting overall survival of patients with endometrial carcinoma. Cancer medicine\| PubMed ID: 29665298	2018
Electron transfer kinetics of the mitochondrial outer membrane protein mitoNEET. Free radical biology & medicine\| PubMed ID: 29704621	2018
A novel RNA sequencing-based miRNA signature predicts with recurrence and outcome of hepatocellular carcinoma. Molecular oncology\| PubMed ID: 29719937	2018
mtDNA Haplogroup N9a Increases the Risk of Type 2 Diabetes by Altering Mitochondrial Function and Intracellular Mitochondrial Signals. Diabetes\| PubMed ID: 29735607	2018
Mebendazole exhibits potent anti-leukemia activity on acute myeloid leukemia. Experimental cell research\| PubMed ID: 29750898	2018
Reverse strand-displacement amplification strategy for rapid detection of p53 gene. Talanta\| PubMed ID: 29853060	2018
Risk factors for extrapulmonary dissemination of tuberculosis and associated mortality during treatment for extrapulmonary tuberculosis. Emerging microbes & infections\| PubMed ID: 29872046	2018
Dataset of mitochondrial genome variants in oncocytic tumors. Data in brief\| PubMed ID: 29876471	2018
[Whole exome sequencing analysis for a Chinese pedigree affected with X-Linked intellectual disability]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics\| PubMed ID: 29896742	2018
Mitoferrin-1 is Involved in the Progression of Alzheimer's Disease Through Targeting Mitochondrial Iron Metabolism in a Caenorhabditis elegans Model of Alzheimer's Disease. Neuroscience\| PubMed ID: 29908215	2018
Exploration of DNA methylation markers for diagnosis and prognosis of patients with endometrial cancer. Epigenetics\| PubMed ID: 29912667	2018
SURF1 mutations in Chinese patients with Leigh syndrome: Novel mutations, mutation spectrum, and the functional consequences. Gene\| PubMed ID: 29933018	2018
Fucosyltransferase 2 induced epithelial-mesenchymal transition via TGF-β/Smad signaling pathway in lung adenocarcinaoma. Experimental cell research\| PubMed ID: 30031128	2018
Nicking-enhanced rolling circle amplification for sensitive fluorescent detection of cancer-related microRNAs. Analytical and bioanalytical chemistry\| PubMed ID: 30066196	2018
Enhanced ROS production leads to excessive fat accumulation through DAF-16 in Caenorhabditis elegans. Experimental gerontology\| PubMed ID: 30120932	2018
TIMMDC1 Knockdown Inhibits Growth and Metastasis of Gastric Cancer Cells through Metabolic Inhibition and AKT/GSK3β/β-Catenin Signaling Pathway. International journal of biological sciences\| PubMed ID: 30123074	2018
A Novel NDUFS3 mutation in a Chinese patient with severe Leigh syndrome. Journal of human genetics\| PubMed ID: 30140060	2018
Correction: A novel NDUFS3 mutation in a Chinese patient with severe Leigh syndrome. Journal of human genetics\| PubMed ID: 30266949	2018
Profiling and targeting of cellular mitochondrial bioenergetics: inhibition of human gastric cancer cell growth by carnosine. Acta pharmacologica Sinica\| PubMed ID: 30560903	2019
The age-related changes and differences in energy metabolism and glutamate-glutamine recycling in the d-gal-induced and naturally occurring senescent astrocytes in vitro. Experimental gerontology\| PubMed ID: 30610899	2019
GALNT6 Promotes Tumorigenicity and Metastasis of Breast Cancer Cell via β-catenin/MUC1-C Signaling Pathway. International journal of biological sciences\| PubMed ID: 30662357	2019
[Variant analysis for a pedigree affected with limb-girdle muscular dystrophy type 2D]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics\| PubMed ID: 30703231	2019
Lipase member H is a downstream molecular target of hypoxia inducible factor-1α and promotes papillary thyroid carcinoma cell migration in BCPAP and KTC-1 cell lines. Cancer management and research\| PubMed ID: 30774423	2019
Zinc Toxicity and Iron-Sulfur Cluster Biogenesis in . Applied and environmental microbiology\| PubMed ID: 30824435	2019
Upregulation of MicroRNA-21 promotes tumorigenesis of prostate cancer cells by targeting KLF5. Cancer biology & therapy\| PubMed ID: 31002531	2019
The protein kinase activity of fructokinase A specifies the antioxidant responses of tumor cells by phosphorylating p62. Science advances\| PubMed ID: 31032410	2019
An eight-year epidemiologic study of head and neck tuberculosis in Texas, USA. Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 31060959	2019
Biodetection and bioremediation of copper ions in environmental water samples using a temperature-controlled, dual-functional Escherichia coli cell. Applied microbiology and biotechnology\| PubMed ID: 31240366	2019
Divergent Peptide Presentations of HLA-A30 Alleles Revealed by Structures With Pathogen Peptides. Frontiers in immunology\| PubMed ID: 31396224	2019
Mutations in TOMM70 lead to multi-OXPHOS deficiencies and cause severe anemia, lactic acidosis, and developmental delay. Journal of human genetics\| PubMed ID: 31907385	2020
Mutations in FASTKD2 are associated with mitochondrial disease with multi-OXPHOS deficiency. Human mutation\| PubMed ID: 31944455	2020
Development of a Sensitive Bioreporter Without Antibiotic Markers for Detecting Bioavailable Copper in Water Environments. Frontiers in microbiology\| PubMed ID: 32038525	2019
Comparison of paired cerebrospinal fluid and serum cell-free mitochondrial and nuclear DNA with copy number and fragment length. Journal of clinical laboratory analysis\| PubMed ID: 32052892	2020
Primaquine phosphate induces the apoptosis of ATRA-resistant acute promyelocytic leukemia cells by inhibition of the NF-κB pathway. Journal of leukocyte biology\| PubMed ID: 32125014	2020
Systematic analysis of a mitochondrial disease-causing ND6 mutation in mitochondrial deficiency. Molecular genetics & genomic medicine\| PubMed ID: 32162843	2020
Removal of Chromium (VI) by Cells Expressing Cytoplasmic or Surface-Displayed ChrB: a Comparative Study. Journal of microbiology and biotechnology\| PubMed ID: 32238765	2020
A simple and rapid protein purification method based on cell-surface display of SUMO-fused recombinant protein and Ulp1 protease. AMB Express\| PubMed ID: 32266507	2020
Association between mitochondrial DNA haplogroup variation and coronary artery disease. Nutrition, metabolism, and cardiovascular diseases : NMCD\| PubMed ID: 32402592	2020
COX6B2 drives metabolic reprogramming toward oxidative phosphorylation to promote metastasis in pancreatic ductal cancer cells. Oncogenesis\| PubMed ID: 32415061	2020
A novel mitochondrial m.14430A>G (MT-ND6, p.W82R) variant causes complex I deficiency and mitochondrial Leigh syndrome. Clinical chemistry and laboratory medicine\| PubMed ID: 32432562	2020
Strict Assembly Restriction of Peptides from Rabbit Hemorrhagic Disease Virus Presented by Rabbit Major Histocompatibility Complex Class I Molecule RLA-A1. Journal of virology\| PubMed ID: 32522857	2020
Islet-cell autoantigen 69 accelerates liver regeneration by downregulating Tgfbr1 and attenuating Tgfβ signaling in mice. FEBS letters\| PubMed ID: 32531799	2020
[Analysis of TWNK variant in a family affected with Perrault syndrome]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics\| PubMed ID: 32619254	2020
Assessment of mitochondrial function in metabolic dysfunction-associated fatty liver disease using obese mouse models. Zoological research\| PubMed ID: 32786176	2020
β-Catenin induces transcriptional expression of PD-L1 to promote glioblastoma immune evasion. The Journal of experimental medicine\| PubMed ID: 32860047	2020
PRRG4 promotes breast cancer metastasis through the recruitment of NEDD4 and downregulation of Robo1. Oncogene\| PubMed ID: 33037408	2020
HMGA2 promotes breast cancer metastasis by modulating Hippo-YAP signaling pathway. Cancer biology & therapy\| PubMed ID: 33307962	2021
Gut microbiome analysis as a predictive marker for the gastric cancer patients. Applied microbiology and biotechnology\| PubMed ID: 33404833	2021
4-Hydroxyphenylpyruvate Dioxygenase-Like Protein Promotes Pancreatic Cancer Cell Progression and Is Associated With Glutamine-Mediated Redox Balance. Frontiers in oncology\| PubMed ID: 33537239	2020
Protein interacting with C-kinase 1 is involved in epithelial-mesenchymal transformation and suppresses progress of gastric cancer. Medical oncology (Northwood, London, England)\| PubMed ID: 33660148	2021