Paul C. Evans

British Heart Foundation Cardiovascular Sciences Unit, Imperial College London

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 29	2012

Other Publications

Article	Year
A novel type of deubiquitinating enzyme. The Journal of biological chemistry\| PubMed ID: 12682062	2003
Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity. The Biochemical journal\| PubMed ID: 14748687	2004
Regulation of pro-inflammatory signalling networks by ubiquitin: identification of novel targets for anti-inflammatory drugs. Expert reviews in molecular medicine\| PubMed ID: 15967057	2005
The triage of damaged proteins: degradation by the ubiquitin-proteasome pathway or repair by molecular chaperones. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 16469848	2006
Laminar shear stress acts as a switch to regulate divergent functions of NF-kappaB in endothelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17557931	2007
Effect of shear stress on vascular inflammation and plaque development. Current opinion in lipidology\| PubMed ID: 17885423	2007
NF-kappaB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling. The Journal of biological chemistry\| PubMed ID: 18178551	2008
KLF2-dependent, shear stress-induced expression of CD59: a novel cytoprotective mechanism against complement-mediated injury in the vasculature. The Journal of biological chemistry\| PubMed ID: 18362151	2008
Elevated p53 expression is associated with dysregulation of the ubiquitin-proteasome system in dilated cardiomyopathy. Cardiovascular research\| PubMed ID: 18375498	2008
Hydrogen peroxide prolongs nuclear localization of NF-kappaB in activated cells by suppressing negative regulatory mechanisms. The Journal of biological chemistry\| PubMed ID: 18474597	2008
Increased endothelial mitogen-activated protein kinase phosphatase-1 expression suppresses proinflammatory activation at sites that are resistant to atherosclerosis. Circulation research\| PubMed ID: 18723442	2008
Hemodynamic parameters regulating vascular inflammation and atherosclerosis: a brief update. Biomedicine & pharmacotherapy = BiomÃ©decine & pharmacothÃ©rapie\| PubMed ID: 18757166	2008
The A20 gene protects kidneys from ischaemia/reperfusion injury by suppressing pro-inflammatory activation. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 18813897	2008
Nur77: orphaned at birth but adopted by the nuclear factor kappaB signaling pathway. Circulation research\| PubMed ID: 19325155	2009
Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothelium exposed to laminar shear stress and impaired by disturbed flow. The Journal of biological chemistry\| PubMed ID: 19457866	2009
Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 19729611	2009
Perfusion of veins at arterial pressure increases the expression of KLF5 and cell cycle genes in smooth muscle cells. Biochemical and biophysical research communications\| PubMed ID: 19958749	2010
c-Jun N-terminal kinase primes endothelial cells at atheroprone sites for apoptosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 20056910	2010
Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium. Free radical biology & medicine\| PubMed ID: 20083195	2010
Role of nuclear factor kappaB in cardiovascular health and disease. Clinical science (London, England : 1979)\| PubMed ID: 20175746	2010
Smooth muscle cells in porcine vein graft intimal hyperplasia are derived from the local vessel wall. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology\| PubMed ID: 20537564	2011
Inhibition of NF-ÎºB signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20833837	2010
The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 20966395	2011
Dexamethasone arterializes venous endothelial cells by inducing mitogen-activated protein kinase phosphatase-1: a novel antiinflammatory treatment for vein grafts? Circulation\| PubMed ID: 21262999	2011
Do miniaturized extracorporeal circuits confer significant clinical benefit without compromising safety? A meta-analysis of randomized controlled trials. ASAIO journal (American Society for Artificial Internal Organs : 1992)\| PubMed ID: 21266906	2011
Disturbed blood flow induces RelA expression via c-Jun N-terminal kinase 1: a novel mode of NF-ÎºB regulation that promotes arterial inflammation. Circulation research\| PubMed ID: 21350211	2011
The role of blood flow in determining the sites of atherosclerotic plaques. F1000 medicine reports\| PubMed ID: 21654925	2011
Heme induces heme oxygenase 1 via Nrf2: role in the homeostatic macrophage response to intraplaque hemorrhage. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21868703	2011
Targeting inhibitor of apoptosis proteins to block vascular inflammation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21918207	2011