Klaas Nicolay

Biomedical Engineering, Eindhoven University of Technology

Affiliated withEindhoven University of Technology

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 29	2012

Other Publications

Article	Year
Improved subtraction by adiabatic FAIR perfusion imaging. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 11810677	2002
The quantitation of ADP diffusion gradients across the outer membrane of heart mitochondria in the presence of macromolecules. Biochimica et biophysica acta\| PubMed ID: 12034470	2002
Diffuse signal abnormalities in the spinal cord in multiple sclerosis: direct postmortem in situ magnetic resonance imaging correlated with in vitro high-resolution magnetic resonance imagin... Annals of neurology\| PubMed ID: 12112117	2002
Role of magnesium in the reduction of ischemic depolarization and lesion volume after experimental subarachnoid hemorrhage. Journal of neurosurgery\| PubMed ID: 12186471	2002
Reduction of cerebral injury in stroke-prone spontaneously hypertensive rats by amlodipine. European journal of pharmacology\| PubMed ID: 12191585	2002
Neuroprotection by selective nitric oxide synthase inhibition at 24 hours after perinatal hypoxia-ischemia. Stroke; a journal of cerebral circulation\| PubMed ID: 12215603	2002
On the role of mi-cK and VDAC in mitochondrial function of heart muscle cells. Molecular biology reports\| PubMed ID: 12241054	2002
Pharmacological interventions in the newborn piglet in the first 24 h after hypoxia-ischemia. A hemodynamic and electrophysiological perspective. Experimental brain research. Experimentelle Hirnforschung. ExpÃ©rimentation cÃ©rÃ©brale\| PubMed ID: 12410335	2002
Acute neuronal injury, excitotoxicity, and the endocannabinoid system. Molecular neurobiology\| PubMed ID: 12428763	2002
In vivo excitotoxicity induced by ouabain, a Na+/K+-ATPase inhibitor. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 12500092	2003
Effects of allopurinol and deferoxamine on reperfusion injury of the brain in newborn piglets after neonatal hypoxia-ischemia. Pediatric research\| PubMed ID: 12815112	2003
Biosynthesis of endocannabinoids and their modes of action in neurodegenerative diseases. Neurotoxicity research\| PubMed ID: 12835123	2003
Effect of vascular crushing on FAIR perfusion kinetics, using a BIR-4 pulse in a magnetization prepared FLASH sequence. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 12939769	2003
Interferon-beta blocks infiltration of inflammatory cells and reduces infarct volume after ischemic stroke in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 12973019	2003
Interferon-beta prevents cytokine-induced neutrophil infiltration and attenuates blood-brain barrier disruption. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 12973022	2003
An MR-compatible device for the in situ assessment of isometric contractile performance of mouse hind-limb ankle flexors. PflÃ¼gers Archiv : European journal of physiology\| PubMed ID: 14530976	2003
Magnetic resonance imaging in experimental models of brain disorders. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 14663334	2003
The mitochondrial outer membrane is not a major diffusion barrier for ADP in mouse heart skinned fibre bundles. PflÃ¼gers Archiv : European journal of physiology\| PubMed ID: 14722773	2004
Comparison of FAIR perfusion kinetics with DSC-MRI and functional histology in a model of transient ischemia. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 14755657	2004
The use of high-resolution magnetic resonance imaging for monitoring interbody fusion and bioabsorbable cages: an ex vivo pilot study. Neurosurgical focus\| PubMed ID: 15198491	2004
MR imaging of mouse leptomeningeal metastases. Journal of neuro-oncology\| PubMed ID: 15218948	2004
A liposomal system for contrast-enhanced magnetic resonance imaging of molecular targets. Bioconjugate chemistry\| PubMed ID: 15264867	2004
In vivo 1H magnetic resonance spectroscopy, T2-weighted and diffusion-weighted MRI during lithium-pilocarpine-induced status epilepticus in the rat. Brain research\| PubMed ID: 15567333	2004
Mitochondrial affinity for ADP is twofold lower in creatine kinase knock-out muscles. Possible role in rescuing cellular energy homeostasis. The FEBS journal\| PubMed ID: 15691329	2005
Determination of mouse skeletal muscle architecture using three-dimensional diffusion tensor imaging. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 15906281	2005
The effect of B1 field inhomogeneity and the nonselective inversion profile on the kinetics of FAIR-based perfusion MRI. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 15906290	2005
MR molecular imaging and fluorescence microscopy for identification of activated tumor endothelium using a bimodal lipidic nanoparticle. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 16204353	2005
Quantum dots with a paramagnetic coating as a bimodal molecular imaging probe. Nano letters\| PubMed ID: 16402777	2006
Intramyocellular lipid content and molecular adaptations in response to a 1-week high-fat diet. Obesity research\| PubMed ID: 16421342	2005
Monitoring of moisture redistribution in multicomponent food systems by use of magnetic resonance imaging. Journal of agricultural and food chemistry\| PubMed ID: 16448166	2006
Lipid-based nanoparticles for contrast-enhanced MRI and molecular imaging. NMR in biomedicine\| PubMed ID: 16450332	2006
Increased resistance to fatigue in creatine kinase deficient muscle is not due to improved contractile economy. PflÃ¼gers Archiv : European journal of physiology\| PubMed ID: 16491397	2006
Liposome-enhanced MRI of neointimal lesions in the ApoE-KO mouse. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 16598732	2006
Annexin A5-functionalized bimodal lipid-based contrast agents for the detection of apoptosis. Bioconjugate chemistry\| PubMed ID: 16704213	2006
Regional variations in intramyocellular lipid concentration correlate with muscle fiber type distribution in rat tibialis anterior muscle. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 16767761	2006
Functional MRI reveals declined prefrontal cortex activation in patients with epilepsy on topiramate therapy. Epilepsy & behavior : E&B\| PubMed ID: 16793345	2006
DTI-based assessment of ischemia-reperfusion in mouse skeletal muscle. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 16826605	2006
Annexin A5-conjugated quantum dots with a paramagnetic lipidic coating for the multimodal detection of apoptotic cells. Bioconjugate chemistry\| PubMed ID: 16848390	2006
1H MR spectroscopy of the brain: absolute quantification of metabolites. Radiology\| PubMed ID: 16864664	2006
Quantitative MRI-pathology correlations of brain white matter lesions developing in a non-human primate model of multiple sclerosis. NMR in biomedicine\| PubMed ID: 16948176	2007
Dynamic MRS and MRI of skeletal muscle function and biomechanics. NMR in biomedicine\| PubMed ID: 17075956	2006
Comparison between prospective and retrospective triggering for mouse cardiac MRI. NMR in biomedicine\| PubMed ID: 17120296	2007
Early in vivo assessment of angiostatic therapy efficacy by molecular MRI. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17202248	2007
Role of ischemia and deformation in the onset of compression-induced deep tissue injury: MRI-based studies in a rat model. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 17255369	2007
Anginex-conjugated liposomes for targeting of angiogenic endothelial cells. Bioconjugate chemistry\| PubMed ID: 17378601	2007
Skeletal muscle degeneration and regeneration after femoral artery ligation in mice: monitoring with diffusion MR imaging. Radiology\| PubMed ID: 17384238	2007
Intersubject differences in the effect of acidosis on phosphocreatine recovery kinetics in muscle after exercise are due to differences in proton efflux rates. American journal of physiology. Cell physiology\| PubMed ID: 17392383	2007
MRI contrast agents: current status and future perspectives. Anti-cancer agents in medicinal chemistry\| PubMed ID: 17504156	2007
Reproducibility of quantitative cerebral T2 relaxometry, diffusion tensor imaging, and 1H magnetic resonance spectroscopy at 3.0 Tesla. Investigative radiology\| PubMed ID: 17507802	2007
Exercise training improves glycemic control in long-standing insulin-treated type 2 diabetic patients. Diabetes care\| PubMed ID: 17626892	2007
多模态成像的磁性和荧光纳米颗粒。 Nanomedicine (London, England)\| PubMed ID: 17716176	2007
Magnetic resonance molecular imaging contrast agents and their application in atherosclerosis. Topics in magnetic resonance imaging : TMRI\| PubMed ID: 18025995	2007
Molecular imaging of macrophages in atherosclerotic plaques using bimodal PEG-micelles. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 18046703	2007
Evaluation of manual and automatic segmentation of the mouse heart from CINE MR images. Journal of magnetic resonance imaging : JMRI\| PubMed ID: 18050352	2008
Improved biocompatibility and pharmacokinetics of silica nanoparticles by means of a lipid coating: a multimodality investigation. Nano letters\| PubMed ID: 18624389	2008
Increased intramyocellular lipid content but normal skeletal muscle mitochondrial oxidative capacity throughout the pathogenesis of type 2 diabetes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 18653763	2008
Short- and long-term limbic abnormalities after experimental febrile seizures. Neurobiology of disease\| PubMed ID: 18707002	2008
Diffusion tensor imaging of left ventricular remodeling in response to myocardial infarction in the mouse. NMR in biomedicine\| PubMed ID: 18780284	2009
A high relaxivity Gd(III)DOTA-DSPE-based liposomal contrast agent for magnetic resonance imaging. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fÃ¼r Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 18940253	2009
Kinetics of avidin-induced clearance of biotinylated bimodal liposomes for improved MR molecular imaging. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 19025910	2008
Paramagnetic lipid-coated silica nanoparticles with a fluorescent quantum dot core: a new contrast agent platform for multimodality imaging. Bioconjugate chemistry\| PubMed ID: 19035793	2008
Improved magnetic resonance molecular imaging of tumor angiogenesis by avidin-induced clearance of nonbound bimodal liposomes. Neoplasia (New York, N.Y.)\| PubMed ID: 19048124	2008
Molecular imaging of tumor angiogenesis using alphavbeta3-integrin targeted multimodal quantum dots. Angiogenesis\| PubMed ID: 19067197	2009
Quantification of left ventricular volumes and ejection fraction in mice using PET, compared with MRI. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 19091898	2009
Well-defined, multifunctional nanostructures of a paramagnetic lipid and a lipopeptide for macrophage imaging. Journal of the American Chemical Society\| PubMed ID: 19105654	2009
Internalization of annexin A5-functionalized iron oxide particles by apoptotic Jurkat cells. Contrast media & molecular imaging\| PubMed ID: 19137542	2009
Three-compartment T1 relaxation model for intracellular paramagnetic contrast agents. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 19215042	2009
Cellular compartmentalization of internalized paramagnetic liposomes strongly influences both T1 and T2 relaxivity. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 19235908	2009
On the use of steady-state signal equations for 2D TrueFISP imaging. Magnetic resonance imaging\| PubMed ID: 19249169	2009
Synergy between anti-CCL2 and docetaxel as determined by DW-MRI in a metastatic bone cancer model. Journal of cellular biochemistry\| PubMed ID: 19259948	2009
Nanoparticulate assemblies of amphiphiles and diagnostically active materials for multimodality imaging. Accounts of chemical research\| PubMed ID: 19435319	2009
Magnitude and control of mitochondrial sensitivity to ADP. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 19622784	2009
Silencing of glycolysis in muscle: experimental observation and numerical analysis. Experimental physiology\| PubMed ID: 19801387	2010
Chitosan-based systems for molecular imaging. Advanced drug delivery reviews\| PubMed ID: 19861142	2010
Adaptations in mitochondrial function parallel, but fail to rescue, the transition to severe hyperglycemia and hyperinsulinemia: a study in Zucker diabetic fatty rats. Obesity (Silver Spring, Md.)\| PubMed ID: 19875988	2010
Diffusion of water in skeletal muscle tissue is not influenced by compression in a rat model of deep tissue injury. Journal of biomechanics\| PubMed ID: 19897200	2010
An MR-compatible bicycle ergometer for in-magnet whole-body human exercise testing. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 19918886	2010
Synergistic targeting of alphavbeta3 integrin and galectin-1 with heteromultivalent paramagnetic liposomes for combined MR imaging and treatment of angiogenesis. Nano letters\| PubMed ID: 19968235	2010
Magnetic quantum dots for multimodal imaging. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology\| PubMed ID: 20049812	2009
Current applications of nanotechnology for magnetic resonance imaging of apoptosis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20217606	2010
MRI-determined carotid artery flow velocities and wall shear stress in a mouse model of vulnerable and stable atherosclerotic plaque. Magma (New York, N.Y.)\| PubMed ID: 20229088	2010
Skeletal muscle metabolic recovery following submaximal exercise in chronic heart failure is limited more by O(2) delivery than O(2) utilization. Clinical science (London, England : 1979)\| PubMed ID: 20310084	2010
Paramagnetic and fluorescent liposomes for target-specific imaging and therapy of tumor angiogenesis. Angiogenesis\| PubMed ID: 20390447	2010
Block-copolymer-stabilized iodinated emulsions for use as CT contrast agents. Biomaterials\| PubMed ID: 20541800	2010
Quantum dots for multimodal molecular imaging of angiogenesis. Angiogenesis\| PubMed ID: 20552267	2010
Quantitative (1)H MRI, (19)F MRI, and (19)F MRS of cell-internalized perfluorocarbon paramagnetic nanoparticles. Contrast media & molecular imaging\| PubMed ID: 20648660	2011
Reproducibility of diffusion tensor imaging in human forearm muscles at 3.0 T in a clinical setting. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 20725932	2010
Surface modification of PLGA nanospheres with Gd-DTPA and Gd-DOTA for high-relaxivity MRI contrast agents. Biomaterials\| PubMed ID: 20797782	2010
Annexin A5-functionalized bimodal nanoparticles for MRI and fluorescence imaging of atherosclerotic plaques. Bioconjugate chemistry\| PubMed ID: 20804153	2010
Contrast enhancement by differently sized paramagnetic MRI contrast agents in mice with two phenotypes of atherosclerotic plaque. Contrast media & molecular imaging\| PubMed ID: 20882509	2011
Mouse myocardial first-pass perfusion MR imaging. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 20928892	2010
Dynamic changes in 1H-MR relaxometric properties of cell-internalized paramagnetic liposomes, as studied over a five-day period. Contrast media & molecular imaging\| PubMed ID: 20936712	2011
Three-dimensional T1 mapping of the mouse heart using variable flip angle steady-state MR imaging. NMR in biomedicine\| PubMed ID: 20960583	2011
Multimodal clinical imaging to longitudinally assess a nanomedical anti-inflammatory treatment in experimental atherosclerosis. Molecular pharmaceutics\| PubMed ID: 21028895	2010
Photochemical activation of endosomal escape of MRI-Gd-agents in tumor cells. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 21053327	2011
The binding of CNA35 contrast agents to collagen fibrils. Chemical communications (Cambridge, England)\| PubMed ID: 21088778	2011
Anti-tumor activity of liposomal glucocorticoids: The relevance of liposome-mediated drug delivery, intratumoral localization and systemic activity. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 21130819	2011
Multi-parametric assessment of the anti-angiogenic effects of liposomal glucocorticoids. Angiogenesis\| PubMed ID: 21225337	2011
Tumor targeting of MMP-2/9 activatable cell-penetrating imaging probes is caused by tumor-independent activation. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 21233187	2011
Similar mitochondrial activation kinetics in wild-type and creatine kinase-deficient fast-twitch muscle indicate significant Pi control of respiration. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 21451138	2011
差异影响的短期和长期高脂肪饮食喂养大鼠肝脂肪酸&#x4EE... Biochimica et biophysica acta\| PubMed ID: 21621638	2011
Fasting-induced myocardial lipid accumulation in long-chain acyl-CoA dehydrogenase knockout mice is accompanied by impaired left ventricular function. Circulation. Cardiovascular imaging\| PubMed ID: 21737602	2011
The effects of deformation, ischemia, and reperfusion on the development of muscle damage during prolonged loading. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 21757578	2011
Target-specific paramagnetic and superparamagnetic micelles for molecular MR imaging. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21874503	2011
Regional contrast agent quantification in a mouse model of myocardial infarction using 3D cardiac T1 mapping. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance\| PubMed ID: 21974927	2011
Pioglitazone modulates vascular inflammation in atherosclerotic rabbits noninvasive assessment with FDG-PET-CT and dynamic contrast-enhanced MR imaging. JACC. Cardiovascular imaging\| PubMed ID: 21999870	2011
Myofibrillar distribution of succinate dehydrogenase activity and lipid stores differs in skeletal muscle tissue of paraplegic subjects. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 22068603	2012
Dual-targeting of Î±(v)Î²(3) and galectin-1 improves the specificity of paramagnetic/fluorescent liposomes to tumor endothelium in vivo. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 22079810	2011
In vivo characterization of a new abdominal aortic aneurysm mouse model with conventional and molecular magnetic resonance imaging. Journal of the American College of Cardiology\| PubMed ID: 22133853	2011
Multitissue assessment of in vivo postprandial intracellular lipid partitioning in rats using localized (1) H-[(13) C] magnetic resonance spectroscopy. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 22213012	2011
Contrast-enhanced MRI of murine myocardial infarction - Part I. NMR in biomedicine\| PubMed ID: 22308108	2012
Molecular MRI of Inflammation in Atherosclerosis. Current cardiovascular imaging reports\| PubMed ID: 22308200	2012
Contrast-enhanced MRI of murine myocardial infarction - Part II. NMR in biomedicine\| PubMed ID: 22311260	2012
Diffusion-tensor MRI reveals the complex muscle architecture of the human forearm. Journal of magnetic resonance imaging : JMRI\| PubMed ID: 22334539	2012