Lloyd A. Greene

Department of Pathology and Cell Biology, Columbia University

Affiliated withColumbia University Columbia University Columbia College

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 44	2009
Publication title Cited by 93	2009

Other Publications

Article	Year
Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins. BMC neuroscience\| PubMed ID: 11922865	2002
Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation. The Journal of biological chemistry\| PubMed ID: 12388545	2002
The basic region and leucine zipper transcription factor MafK is a new nerve growth factor-responsive immediate early gene that regulates neurite outgrowth. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12388604	2002
Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12486162	2002
POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis. The EMBO journal\| PubMed ID: 12514131	2003
Regulated expression of ATF5 is required for the progression of neural progenitor cells to neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12805299	2003
Malignant pheochromocytoma: current status and initiatives for future progress. Endocrine-related cancer\| PubMed ID: 15369446	2004
B-myb and C-myb play required roles in neuronal apoptosis evoked by nerve growth factor deprivation and DNA damage. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15470138	2004
Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15537872	2004
Analysis of gene expression changes in a cellular model of Parkinson disease. Neurobiology of disease\| PubMed ID: 15649696	2005
Regulation of neuron survival and death by p130 and associated chromatin modifiers. Genes & development\| PubMed ID: 15769944	2005
Downregulation of activating transcription factor 5 is required for differentiation of neural progenitor cells into astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15829641	2005
ATF5 regulates the proliferation and differentiation of oligodendrocytes. Molecular and cellular neurosciences\| PubMed ID: 15950153	2005
CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism. Journal of neurochemistry\| PubMed ID: 16135078	2005
Bim is a direct target of a neuronal E2F-dependent apoptotic pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16162916	2005
Puma and p53 play required roles in death evoked in a cellular model of Parkinson disease. Neurochemical research\| PubMed ID: 16187218	2005
Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis. The Journal of biological chemistry\| PubMed ID: 16230351	2006
Regulation of apoptotic c-Jun N-terminal kinase signaling by a stabilization-based feed-forward loop. Molecular and cellular biology\| PubMed ID: 16260609	2005
You can't go home again: transcriptionally driven alteration of cell signaling by NGF. Neurochemical research\| PubMed ID: 16341597	2005
Activation of the apoptotic JNK pathway through the Rac1-binding scaffold protein POSH. Methods in enzymology\| PubMed ID: 16472680	2006
Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs. The Journal of biological chemistry\| PubMed ID: 16571722	2006
RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivati... The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17005863	2006
Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model. The Journal of biological chemistry\| PubMed ID: 17095503	2007
Cell cycle molecules define a pathway required for neuron death in development and disease. Biochimica et biophysica acta\| PubMed ID: 17229557	2007
Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17251431	2007
The transcription factor ATF5 is widely expressed in carcinomas, and interference with its function selectively kills neoplastic, but not nontransformed, breast cell lines. International journal of cancer. Journal international du cancer\| PubMed ID: 17266024	2007
Pro-apoptotic Bim induction in response to nerve growth factor deprivation requires simultaneous activation of three different death signaling pathways. The Journal of biological chemistry\| PubMed ID: 17702754	2007
Identification of POSH2, a novel homologue of the c-Jun N-terminal kinase scaffold protein POSH. Developmental neuroscience\| PubMed ID: 17762203	2007
Glucagon-like peptide-1 (GLP-1) diminishes neuronal degeneration and death caused by NGF deprivation by suppressing Bim induction. Neurochemical research\| PubMed ID: 18351462	2008
The transcription factor ATF5: role in neurodevelopment and neural tumors. Journal of neurochemistry\| PubMed ID: 19046351	2009
RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19118169	2008
Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps. Apoptosis : an international journal on programmed cell death\| PubMed ID: 19165601	2009
Identification of a novel DNA binding site and a transcriptional target for activating transcription factor 5 in c6 glioma and mcf-7 breast cancer cells. Molecular cancer research : MCR\| PubMed ID: 19531563	2009
Cbl negatively regulates JNK activation and cell death. Cell research\| PubMed ID: 19546888	2009
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20089925	2010
Sertad1 plays an essential role in developmental and pathological neuron death. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20237268	2010
RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21368030	2011
Gata2 is required for migration and differentiation of retinorecipient neurons in the superior colliculus. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21430145	2011
Akt as a victim, villain and potential hero in Parkinson's disease pathophysiology and treatment. Cellular and molecular neurobiology\| PubMed ID: 21547489	2011
Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cells. Developmental neurobiology\| PubMed ID: 22095825	2011
Sh3rf2/POSHER Protein Promotes Cell Survival by Ring-mediated Proteasomal Degradation of the c-Jun N-terminal Kinase Scaffold POSH (Plenty of SH3s) Protein. The Journal of biological chemistry\| PubMed ID: 22128169	2012