GV

Giuseppe Valacchi

Department of Biomedical and Specialist Surgical Sciences, University of ferrara

Affiliated withUniversity of ferraraNorth Carolina State University

Research Area

Biography

Giuseppe Valacchi obtained his B.S. with Laude in physiology, MS in physiopathology and his PhD degree in Cell Physiology and Neuroimmuno-physiology at the University of Siena. During his training he has worked as “exchange PhD student" in the “Department of Molecular and Cell Biology at the University of California at Berkeley" where he started out his studies on the effect of environmental oxidative stress such as O3 and UV on skin physiology. After his PhD graduation, he continued working as Post Doc at the University of Berkeley, California (USA) then in the “Department of Internal Medicine" and in the "Department of Nutrition" at the University of California at Davis (UCD). In 2005 he become Faculty and member of the Academic Federation in the Department of Internal Medicine (UCD). At the end of 2006 he was awarded with the “progetto rientro dei cervelli”, granted by the Italian Ministry of Health and returned to Italy at the University of Siena as Assistant Professor until 2011. In 2011 he was appointed as Associate Professor in Physiology at the University of Ferrara and in 2021 was promoted to Full Professor in Physiology. From 2008 is also Adjunct Prof. at Kyung Hee University, Seoul, South Korea and starting from August 2016 he is a Professor in Regenerative Medicine at North Caroline State University.

His research has been focused in understanding the cellular, and molecular mechanisms that define the tissues physio-pathological responses to altered redox homeostasis with special focus on cutaneous tissue. He is a member of the SFRR Europe Council since 2017 and he is author of more than 270 peer reviewed internationals papers (most of them related to the effect of pollution in target organs), 15 book chapters, one book. He has been invited speaker to more than 100 international conferences and organizer/Chair to over 50 international meetings. He has won several awards among them the Entelligence Award from Actelion, OCC Young Investigator Award, Science and Education Award and recently, in 2019, the Exposome grant.

In 2018 he was awarded with the “Doctorate Honoris Causa” in Biochemistry and Pharmacy from the University of Buenos Aires (rank n. 72 among the over 3,000 universities in the world) for his work in the redox biology field, in addition he is the recipient of the 2020 Clinical Research award from the SFRR-E.

He is the Associate Editor of several international journals among which is Mediators of Inflammation, Frontiers in Cellular Biochemistry, World Research Journal of Biochemistry, Journal of Complementary and Traditional Medicine, Biomed Research International (Dermatology Subjects), Oxidative Medicine and Cellular Longevity, Antioxidants; in addition he is member of the Editorial Board of several journals including Genes and Nutrition, Open Biochemistry Journal, Archives in Biophysics and Biochemistry, Clinical Immunology Endocrine & Metabolic Drugs, Frontiers in Inflammation Pharmacology, Clinical Anti-Inflammatory & Anti-Allergy Drugs, BioFactors, Cosmetics, Free Radicals in Biology and Medicine.

JoVE Journal Publications

ArticleTotal : 1
Year
Cultivating a Three-dimensional Reconstructed Human Epidermis at a Large Scale
Publication title

Cited by 9

2021

Other Publications

Article
Year
F2-dihomo-isoprostanes as potential early biomarkers of lipid oxidative damage in Rett syndrome.

Journal of lipid research| PubMed ID: 21917727

2011
Scavenger receptor class B type I: a multifunctional receptor.

Annals of the New York Academy of Sciences| PubMed ID: 22239457

2011
2012
2012
2012
2012
Cutaneous responses to environmental stressors.

Annals of the New York Academy of Sciences| PubMed ID: 23050967

2012
Alternative Pathways of Cancer Cell Death by Rottlerin: Apoptosis versus Autophagy.

Evidence-based complementary and alternative medicine : eCAM| PubMed ID: 23320042

2012
2013
2013
Antiangiogenic VEGF isoform in inflammatory myopathies.

Mediators of inflammation| PubMed ID: 23840094

2013
2013
2013
2014
Effect of nanostructured lipid vehicles on percutaneous absorption of curcumin.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V| PubMed ID: 24361485

2014
2013
2013
2013
2013
2013
Subclinical inflammatory status in Rett syndrome.

Mediators of inflammation| PubMed ID: 24511209

2014
2014
2014
2014
The Magic Velvet Bean of Mucuna pruriens.

Journal of traditional and complementary medicine| PubMed ID: 24716148

2012
Inflammatory lung disease in Rett syndrome.

Mediators of inflammation| PubMed ID: 24757286

2014
2014
ASD: biochemical mechanisms behind behavioral disorders.

Mediators of inflammation| PubMed ID: 24799768

2014
Comparative effects between electronic and cigarette smoke in human keratinocytes and epithelial lung cells.

Toxicology in vitro : an international journal published in association with BIBRA| PubMed ID: 24809892

2014
Redox imbalance and morphological changes in skin fibroblasts in typical Rett syndrome.

Oxidative medicine and cellular longevity| PubMed ID: 24987493

2014
2014
2014
2014
2014
2015
2014
Nrf2 activation as target to implement therapeutic treatments.

Frontiers in chemistry| PubMed ID: 25699252

2015
2015
2015
2015
2015
2015
2015
2015
Antiproliferative Effect of Rottlerin on Sk-Mel-28 Melanoma Cells.

Evidence-based complementary and alternative medicine : eCAM| PubMed ID: 26161122

2015
2015
Ambient ozone and bacterium Streptococcus: A link between cellulitis and pharyngitis.

International journal of occupational medicine and environmental health| PubMed ID: 26216315

2015
2015
2015
2014
2016
2016
Skin Damage Mechanisms Related to Airborne Particulate Matter Exposure.

Toxicological sciences : an official journal of the Society of Toxicology| PubMed ID: 26507108

2016
Oxidative challenge in Alzheimer's disease: state of knowledge and future needs.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research| PubMed ID: 26755810

2016
2016
2016
2016
2017
2016
2016
2016
OxInflammation in Rett syndrome.

The international journal of biochemistry & cell biology| PubMed ID: 27425398

2016
2016
Ozone mediators effect on "in vitro" scratch wound closure.

Free radical research| PubMed ID: 27487012

2016
Proteomic analysis of 4-hydroxynonenal and nitrotyrosine modified proteins in RTT fibroblasts.

The international journal of biochemistry & cell biology| PubMed ID: 27495376

2016
Redox regulation of inflammatory processes.

The international journal of biochemistry & cell biology| PubMed ID: 27818335

2016
SRB1 as a new redox target of cigarette smoke in human sebocytes.

Free radical biology & medicine| PubMed ID: 27865981

2017
2017
2017
2017
2017
2017
2017
2017
Monoolein aqueous dispersions as a delivery system for quercetin.

Biomedical microdevices| PubMed ID: 28484916

2017
Mediterranean lifestyle and cardiovascular disease prevention.

Cardiovascular diagnosis and therapy| PubMed ID: 28529921

2017
2017
2017
2018
2017
2018
Paraoxonase, arylesterase and lactonase activities of paraoxonase-1 (PON1) in obese and severely obese women.

Scandinavian journal of clinical and laboratory investigation| PubMed ID: 29168398

2018
2017
2018
Potassium Ascorbate with Ribose: Promising Therapeutic Approach for Melanoma Treatment.

Oxidative medicine and cellular longevity| PubMed ID: 29290903

2017
2017
2018
2018
Atmospheric skin aging-Contributors and inhibitors.

Journal of cosmetic dermatology| PubMed ID: 29575554

2018
2018
2018
2018
2018
2018
2018
2018
2019
SR-B1 involvement in keratinocytes in vitro wound closure.

Archives of biochemistry and biophysics| PubMed ID: 30240595

2018
2018
2019
2019
2018
2019
2019
2019
Involvement of cutaneous SR-B1 in skin lipid homeostasis.

Archives of biochemistry and biophysics| PubMed ID: 30876920

2019
Involvement of 4-hydroxy-2-nonenal in pollution-induced skin damage.

BioFactors (Oxford, England)| PubMed ID: 31087730

2019
Ozonated Oils and Cutaneous Wound Healing.

Current pharmaceutical design| PubMed ID: 31267858

2019
Multiple mechanisms of Rottlerin toxicity in A375 melanoma cells.

BioFactors (Oxford, England)| PubMed ID: 31408224

2019
Lipid nanostructures for antioxidant delivery: a comparative preformulation study.

Beilstein journal of nanotechnology| PubMed ID: 31501750

2019
2019
2020
2020
Mimicking cigarette smoke exposure to assess cutaneous toxicity.

Toxicology in vitro : an international journal published in association with BIBRA| PubMed ID: 31669394

2020
2020
2020
2019
Redox regulation of cutaneous inflammasome by ozone exposure.

Free radical biology & medicine| PubMed ID: 31778733

2020
Skin Health from the Inside Out.

Annual review of food science and technology| PubMed ID: 31905017

2020
2020
Compromised immune/inflammatory responses in Rett syndrome.

Free radical biology & medicine| PubMed ID: 32119978

2020
2020
Alterations of mitochondrial bioenergetics, dynamics, and morphology support the theory of oxidative damage involvement in autism spectrum disorder.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology| PubMed ID: 32246805

2020
The PDE4 inhibitor CHF6001 affects keratinocyte proliferation via cellular redox pathways.

Archives of biochemistry and biophysics| PubMed ID: 32268137

2020
2020
2020
Circadian Clock and OxInflammation: Functional Crosstalk in Cutaneous Homeostasis.

Oxidative medicine and cellular longevity| PubMed ID: 32377292

2020
Particulate Matter Decreases Intestinal Barrier-Associated Proteins Levels in 3D Human Intestinal Model.

International journal of environmental research and public health| PubMed ID: 32384765

2020
Nanoparticulate Gels for Cutaneous Administration of Caffeic Acid.

Nanomaterials (Basel, Switzerland)| PubMed ID: 32443503

2020
Particulate Matter Induces Tissue OxInflammation: From Mechanism to Damage.

Antioxidants & redox signaling| PubMed ID: 32443938

2020
Proteomic profiling reveals mitochondrial alterations in Rett syndrome.

Free radical biology & medicine| PubMed ID: 32445864

2020
2020
2020
Evaluation of oxidative damage and Nrf2 activation by combined pollution exposure in lung epithelial cells.

Environmental science and pollution research international| PubMed ID: 32504424

2020
2020
KRIT1 as a possible new player in melanoma aggressiveness.

Archives of biochemistry and biophysics| PubMed ID: 32735866

2020
2020
2020
2020
Postexercise Inflammasome Activation and IL-1β Production Mitigated by Flavonoid Supplementation in Cyclists.

International journal of sport nutrition and exercise metabolism| PubMed ID: 32932235

2020
2021
Bench approaches to study the detrimental cutaneous impact of tropospheric ozone.

Journal of exposure science & environmental epidemiology| PubMed ID: 33127990

2021
2020
Evaluating the effect of ozone in UV induced skin damage.

Toxicology letters| PubMed ID: 33279629

2021
Inflammasome Activation in Pollution-Induced Skin Conditions.

Plastic and reconstructive surgery| PubMed ID: 33347070

2021
2021
Impaired mitochondrial quality control in Rett Syndrome.

Archives of biochemistry and biophysics| PubMed ID: 33549528

2021
2021
2021
2021
2021
2021