John Greenwood

UCL Institute of Ophthalmology, University College London

Affiliated withUniversity College London

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 13	2022

Other Publications

Article	Year
SV40 large T immortalised cell lines of the rat blood-brain and blood-retinal barriers retain their phenotypic and immunological characteristics. Journal of neuroimmunology\| PubMed ID: 8982103	1996
Subretinal transplantation of genetically modified human cell lines attenuates loss of visual function in dystrophic rats. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11504951	2001
Characterization of genetically modified human retinal pigment epithelial cells developed for in vitro and transplantation studies. Investigative ophthalmology & visual science\| PubMed ID: 11818403	2002
Inhibition of Rho GTPases with protein prenyltransferase inhibitors prevents leukocyte recruitment to the central nervous system and attenuates clinical signs of disease in an animal model o... Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11937568	2002
Lymphocyte trafficking through the blood-brain barrier is dependent on endothelial cell heterotrimeric G-protein signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12153986	2002
Ezrin and moesin co-localise with ICAM-1 in brain endothelial cells but are not directly associated. Brain research. Molecular brain research\| PubMed ID: 12399107	2002
Lymphocyte migration into the central nervous system: implication of ICAM-1 signalling at the blood-brain barrier. Vascular pharmacology\| PubMed ID: 12529926	2002
Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12626426	2003
Changes in cytoskeletal and tight junctional proteins correlate with decreased permeability induced by dexamethasone in cultured rat brain endothelial cells. Neuroscience letters\| PubMed ID: 12782340	2003
Potential of statins for the treatment of multiple sclerosis. The Lancet. Neurology\| PubMed ID: 12849290	2003
Intracellular domain of brain endothelial intercellular adhesion molecule-1 is essential for T lymphocyte-mediated signaling and migration. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12902516	2003
Oxidative stress affects the junctional integrity of retinal pigment epithelial cells. Investigative ophthalmology & visual science\| PubMed ID: 14744914	2004
Basement membrane-dependent modification of phenotype and gene expression in human retinal pigment epithelial ARPE-19 cells. Investigative ophthalmology & visual science\| PubMed ID: 15277505	2004
Suppression of autoimmune retinal disease by lovastatin does not require Th2 cytokine induction. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15699169	2005
Pharmacological targeting of ICAM-1 signaling in brain endothelial cells: potential for treating neuroinflammation. Cellular and molecular neurobiology\| PubMed ID: 15962512	2005
Statin therapy and autoimmune disease: from protein prenylation to immunomodulation. Nature reviews. Immunology\| PubMed ID: 16639429	2006
Statins and the vascular endothelial inflammatory response. Trends in immunology\| PubMed ID: 17197237	2007
Dopamine neurones form a discrete plexus with melanopsin cells in normal and degenerating retina. Experimental neurology\| PubMed ID: 17362933	2007
Preservation of visual cortical function following retinal pigment epithelium transplantation in the RCS rat using optical imaging techniques. The European journal of neuroscience\| PubMed ID: 17439483	2007
Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17921253	2007
Phosphorylation of vascular endothelial cadherin controls lymphocyte emigration. Journal of cell science\| PubMed ID: 18096689	2008
ICAM-1-mediated endothelial nitric oxide synthase activation via calcium and AMP-activated protein kinase is required for transendothelial lymphocyte migration. Molecular biology of the cell\| PubMed ID: 19073885	2009
Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina. Molecular biology of the cell\| PubMed ID: 19587120	2009
Positional averaging explains crowding with letter-like stimuli. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19617570	2009
Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+ T cells during aging. The Journal of experimental medicine\| PubMed ID: 19667063	2009
Genetic ablation of retinal pigment epithelial cells reveals the adaptive response of the epithelium and impact on photoreceptors. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19850870	2009
The RhoA activator GEF-H1/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration. Molecular biology of the cell\| PubMed ID: 20089843	2010
Crowding changes appearance. Current biology : CB\| PubMed ID: 20206527	2010
Probabilistic, positional averaging predicts object-level crowding effects with letter-like stimuli. Journal of vision\| PubMed ID: 20884479	2010
Review: leucocyte-endothelial cell crosstalk at the blood-brain barrier: a prerequisite for successful immune cell entry to the brain. Neuropathology and applied neurobiology\| PubMed ID: 20946472	2011
Analysis of candidate genes for macular telangiectasia type 2. Molecular vision\| PubMed ID: 21179236	2010
The expression of retinal cell markers in human retinal pigment epithelial cells and their augmentation by the synthetic retinoid fenretinide. Molecular vision\| PubMed ID: 21738400	2011
Crowding is tuned for perceived (not physical) location. Journal of vision\| PubMed ID: 21824980	2011
Apelin is required for non-neovascular remodeling in the retina. The American journal of pathology\| PubMed ID: 22067912	2012
A common visual metric for approximate number and density. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22106276	2011
Crowding follows the binding of relative position and orientation. Journal of vision\| PubMed ID: 22438467	2012
The neural correlates of crowding-induced changes in appearance. Current biology : CB\| PubMed ID: 22658599	2012
Number and density discrimination rely on a common metric: Similar psychophysical effects of size, contrast, and divided attention. Journal of vision\| PubMed ID: 22665458	2012
Visual acuity, crowding, and stereo-vision are linked in children with and without amblyopia. Investigative ophthalmology & visual science\| PubMed ID: 23074213	2012
Rationale and design of the PRognostic Importance of MIcrovascular Dysfunction in asymptomatic patients with Aortic Stenosis (PRIMID-AS): a multicentre observational study with blinded inves... BMJ open\| PubMed ID: 24353258	2013
Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial. Lancet (London, England)\| PubMed ID: 24655729	2014
Probing the biomechanical contribution of the endothelium to lymphocyte migration: diapedesis by the path of least resistance. Journal of cell science\| PubMed ID: 25002404	2014
Crowding is reduced by onset transients in the target object (but not in the flankers). Journal of vision\| PubMed ID: 25086085	2014
Differential apicobasal VEGF signaling at vascular blood-neural barriers. Developmental cell\| PubMed ID: 25175707	2014
Foveal target repetitions reduce crowding. Journal of vision\| PubMed ID: 25294741	2014
Randomized trial of complete versus lesion-only revascularization in patients undergoing primary percutaneous coronary intervention for STEMI and multivessel disease: the CvLPRIT trial. Journal of the American College of Cardiology\| PubMed ID: 25766941	2015
Splenic Switch-off: A Tool to Assess Stress Adequacy in Adenosine Perfusion Cardiac MR Imaging. Radiology\| PubMed ID: 25923223	2015
Mineralocorticoid receptor antagonist pretreatment to MINIMISE reperfusion injury after ST-elevation myocardial infarction (the MINIMISE STEMI Trial): rationale and study design. Clinical cardiology\| PubMed ID: 25990305	2015
Retinal Pigment Epithelial Cells Mitigate the Effects of Complement Attack by Endocytosis of C5b-9. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26324770	2015
The fetal mouse metatarsal bone explant as a model of angiogenesis. Nature protocols\| PubMed ID: 26334866	2015
Complete Versus Lesion-Only Primary PCI: The Randomized Cardiovascular MR CvLPRIT Substudy. Journal of the American College of Cardiology\| PubMed ID: 26700834	2015
Categorical information influences conscious perception: An interaction between object-substitution masking and repetition blindness. Attention, perception & psychophysics\| PubMed ID: 26902249	2016
Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours. Ecancermedicalscience\| PubMed ID: 27110286	2016
Infarct Size Following Treatment With Second- Versus Third-Generation P2Y12 Antagonists in Patients With Multivessel Coronary Disease at ST-Segment Elevation Myocardial Infarction in the CvL... Journal of the American Heart Association\| PubMed ID: 27247336	2016
Cortical idiosyncrasies predict the perception of object size. Nature communications\| PubMed ID: 27357864	2016
Childhood amblyopia: current management and new trends. British medical bulletin\| PubMed ID: 27543498	2016
The orientation selectivity of face identification. Scientific reports\| PubMed ID: 27677359	2016
Infarct size following complete revascularization in patients presenting with STEMI: a comparison of immediate and staged in-hospital non-infarct related artery PCI subgroups in the CvLPRIT ... Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance\| PubMed ID: 27842548	2016
Comparison of exercise testing and CMR measured myocardial perfusion reserve for predicting outcome in asymptomatic aortic stenosis: the PRognostic Importance of MIcrovascular Dysfunction in... European heart journal\| PubMed ID: 28204448	2017
Endothelial MAPKs Direct ICAM-1 Signaling to Divergent Inflammatory Functions. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 28373581	2017
Variations in crowding, saccadic precision, and spatial localization reveal the shared topology of spatial vision. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28396415	2017
Binocular Therapy for Childhood Amblyopia Improves Vision Without Breaking Interocular Suppression. Investigative ophthalmology & visual science\| PubMed ID: 28614556	2017
Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017. Fluids and barriers of the CNS\| PubMed ID: 29110676	2017
Computational tools for clinical support: a multi-scale compliant model for haemodynamic simulations in an aortic dissection based on multi-modal imaging data. Journal of the Royal Society, Interface\| PubMed ID: 29118115	2017
Correction to: Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017. Fluids and barriers of the CNS\| PubMed ID: 29329565	2018
Myocardial Scar and Mortality in Severe Aortic Stenosis. Circulation\| PubMed ID: 30002099	2018
Crowding for faces is determined by visual (not holistic) similarity: Evidence from judgements of eye position. Scientific reports\| PubMed ID: 30135454	2018
Mineralocorticoid receptor antagonist pre-treatment and early post-treatment to minimize reperfusion injury after ST-elevation myocardial infarction: The MINIMIZE STEMI trial. American heart journal\| PubMed ID: 30893577	2019
Rationale and design of the randomized, controlled Early Valve Replacement Guided by Biomarkers of Left Ventricular Decompensation in Asymptomatic Patients with Severe Aortic Stenosis (EVOLV... American heart journal\| PubMed ID: 30978556	2019
Applying causal models to explore the mechanism of action of simvastatin in progressive multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 31072935	2019
Population receptive field estimates for motion-defined stimuli. NeuroImage\| PubMed ID: 31158480	2019
Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease. The New England journal of medicine\| PubMed ID: 31216398	2019
Sex differences in left ventricular remodelling, myocardial fibrosis and mortality after aortic valve replacement. Heart (British Cardiac Society)\| PubMed ID: 31467152	2019
Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial. Lancet (London, England)\| PubMed ID: 31500849	2019
A Multicenter, Scan-Rescan, Human and Machine Learning CMR Study to Test Generalizability and Precision in Imaging Biomarker Analysis. Circulation. Cardiovascular imaging\| PubMed ID: 31547689	2019
Extracellular Myocardial Volume in Patients With Aortic Stenosis. Journal of the American College of Cardiology\| PubMed ID: 31976869	2020
Dissociable effects of visual crowding on the perception of color and motion. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32193344	2020
T mapping performance and measurement repeatability: results from the multi-national T mapping standardization phantom program (T1MES). Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance\| PubMed ID: 32375896	2020
A Multifunctional Role of Leucine-Rich α-2-Glycoprotein 1 in Cutaneous Wound Healing Under Normal and Diabetic Conditions. Diabetes\| PubMed ID: 32887674	2020
Evaluation of real-world early response of DMO to aflibercept therapy to inform future clinical trial design of novel investigational agents. Scientific reports\| PubMed ID: 33020570	2020
Endothelial Protease Activated Receptor 1 (PAR1) Signalling Is Required for Lymphocyte Transmigration across Brain Microvascular Endothelial Cells. Cells\| PubMed ID: 33371217	2020
Small-molecule antagonist of VLA-4 (GW559090) attenuated neuro-inflammation by targeting Th17 cell trafficking across the blood-retinal barrier in experimental autoimmune uveitis. Journal of neuroinflammation\| PubMed ID: 33602234	2021
Topographical Response of Retinal Neovascularization to Aflibercept or Panretinal Photocoagulation in Proliferative Diabetic Retinopathy: Post Hoc Analysis of the CLARITY Randomized Clinical... JAMA ophthalmology\| PubMed ID: 33704351	2021
Diagnosis and risk stratification in hypertrophic cardiomyopathy using machine learning wall thickness measurement: a comparison with human test-retest performance. The Lancet. Digital health\| PubMed ID: 33735065	2021
Regional variation in cardiovascular magnetic resonance service delivery across the UK. Heart (British Cardiac Society)\| PubMed ID: 33766986	2021
Prospective Case-Control Study of Cardiovascular Abnormalities 6 Months Following Mild COVID-19 in Healthcare Workers. JACC. Cardiovascular imaging\| PubMed ID: 33975819	2021
Demographic, multi-morbidity and genetic impact on myocardial involvement and its recovery from COVID-19: protocol design of COVID-HEART-a UK, multicentre, observational study. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance\| PubMed ID: 34112195	2021
Heritable functional architecture in human visual cortex. NeuroImage\| PubMed ID: 34153449	2021
Markers of Myocardial Damage Predict Mortality in Patients With Aortic Stenosis. Journal of the American College of Cardiology\| PubMed ID: 34353531	2021
Leucine-rich alpha-2-glycoprotein 1 (LRG1) as a novel ADC target. RSC chemical biology\| PubMed ID: 34458833	2021
The "Neuro-Glial-Vascular" Unit: The Role of Glia in Neurovascular Unit Formation and Dysfunction. Frontiers in cell and developmental biology\| PubMed ID: 34646826	2021
Effect of remote ischaemic conditioning on infarct size and remodelling in ST-segment elevation myocardial infarction patients: the CONDI-2/ERIC-PPCI CMR substudy. Basic research in cardiology\| PubMed ID: 34648075	2021
Phenotyping hypertrophic cardiomyopathy using cardiac diffusion magnetic resonance imaging: the relationship between microvascular dysfunction and microstructural changes. European heart journal. Cardiovascular Imaging\| PubMed ID: 34694365	2021
CCL4 induces inflammatory signalling and barrier disruption in the neurovascular endothelium. Brain, behavior, & immunity - health\| PubMed ID: 34755124	2021
Eye movements elevate crowding in idiopathic infantile nystagmus syndrome. Journal of vision\| PubMed ID: 34935877	2021
LRG1 as a novel therapeutic target in eye disease. Eye (London, England)\| PubMed ID: 34987199	2022