John B. Bruning

School of Biological Sciences, The University of Adelaide

Affiliated withThe University of Adelaide

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2021

Other Publications

Article	Year
Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function. PloS one\| PubMed ID: 24465693	2014
Macrocyclic protease inhibitors with reduced peptide character. Angewandte Chemie (International ed. in English)\| PubMed ID: 24903745	2014
New insights into the evolutionary history of plant sorbitol dehydrogenase. BMC plant biology\| PubMed ID: 25879735	2015
Pharmacological repression of PPARγ promotes osteogenesis. Nature communications\| PubMed ID: 26068133	2015
Structural mechanism for signal transduction in RXR nuclear receptor heterodimers. Nature communications\| PubMed ID: 26289479	2015
Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism. PPAR research\| PubMed ID: 26435709	2015
SR2067 Reveals a Unique Kinetic and Structural Signature for PPARγ Partial Agonism. ACS chemical biology\| PubMed ID: 26579553	2016
Structure of the sliding clamp from the fungal pathogen Aspergillus fumigatus (AfumPCNA) and interactions with Human p21. The FEBS journal\| PubMed ID: 28165677	2017
Structure-Activity Relationship of 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (INT131) Analogs for PPARγ-Targeted Antidiabetics. Journal of medicinal chemistry\| PubMed ID: 28485590	2017
X-ray crystal structure of rivoglitazone bound to PPARγ and PPAR subtype selectivity of TZDs. Biochimica et biophysica acta. General subjects\| PubMed ID: 28499821	2017
HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions. Nature communications\| PubMed ID: 29030554	2017
Rational Design of a 3 -Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 29917264	2018
PPARγ in Complex with an Antagonist and Inverse Agonist: a Tumble and Trap Mechanism of the Activation Helix. iScience\| PubMed ID: 30123887	2018
Chemical Crosslinking Mass Spectrometry Reveals the Conformational Landscape of the Activation Helix of PPARγ; a Model for Ligand-Dependent Antagonism. Structure (London, England : 1993)\| PubMed ID: 30146169	2018
Precipitant-ligand exchange technique reveals the ADP binding mode in Mycobacterium tuberculosis dethiobiotin synthetase. Acta crystallographica. Section D, Structural biology\| PubMed ID: 30289406	2018
Structure, Mechanism, and Inhibition of Thioredoxin Reductase. Antimicrobial agents and chemotherapy\| PubMed ID: 30642940	2019
Shooting three inflammatory targets with a single bullet: Novel multi-targeting anti-inflammatory glitazones. European journal of medicinal chemistry\| PubMed ID: 30818268	2019
Structural and Dynamic Elucidation of a Non-acid PPAR Partial Agonist: SR1988. Nuclear receptor research\| PubMed ID: 30906767	2018
Obtaining Crystals of PPARγ Ligand Binding Domain Bound to Small Molecules. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 31041754	2019
Combining random microseed matrix screening and the magic triangle for the efficient structure solution of a potential lysin from bacteriophage P68. Acta crystallographica. Section D, Structural biology\| PubMed ID: 31282476	2019
An aldo-keto reductase with 2-keto-l-gulonate reductase activity functions in l-tartaric acid biosynthesis from vitamin C in . The Journal of biological chemistry\| PubMed ID: 31488549	2019
d-Alanine-d-alanine ligase as a model for the activation of ATP-grasp enzymes by monovalent cations. The Journal of biological chemistry\| PubMed ID: 32335509	2020
Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase. The FEBS journal\| PubMed ID: 33089641	2020
Vanishing white matter: Eukaryotic initiation factor 2B model and the impact of missense mutations. Molecular genetics & genomic medicine\| PubMed ID: 33432707	2021