Malgorzata Zakrzewska

Department of Protein Engineering, University of Wroclaw

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2021

Other Publications

Article	Year
Design of fully active FGF-1 variants with increased stability. Protein engineering, design & selection : PEDS\| PubMed ID: 15469994	2004
The many faces of protease-protein inhibitor interaction. The EMBO journal\| PubMed ID: 15775973	2005
Highly stable mutants of human fibroblast growth factor-1 exhibit prolonged biological action. Journal of molecular biology\| PubMed ID: 16126225	2005
Structural requirements of FGF-1 for receptor binding and translocation into cells. Biochemistry\| PubMed ID: 17176056	2006
FGF-1: from biology through engineering to potential medical applications. Critical reviews in clinical laboratory sciences\| PubMed ID: 18293181	2008
Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus. Molecular and cellular biology\| PubMed ID: 18411303	2008
Structure of a highly stable mutant of human fibroblast growth factor 1. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 19153468	2009
Increased protein stability of FGF1 can compensate for its reduced affinity for heparin. The Journal of biological chemistry\| PubMed ID: 19574212	2009
Longer action means better drug: tuning up protein therapeutics. Biotechnology advances\| PubMed ID: 21443940	2011
Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling. PloS one\| PubMed ID: 21779335	2011
Tailoring small proteins towards biomedical applications. Current pharmaceutical biotechnology\| PubMed ID: 21902634	2011
FGF1-gold nanoparticle conjugates targeting FGFR efficiently decrease cell viability upon NIR irradiation. International journal of nanomedicine\| PubMed ID: 23226697	2012
Protease resistant variants of FGF1 with prolonged biological activity. Protein and peptide letters\| PubMed ID: 24304385	2014
Nucleolin regulates phosphorylation and nuclear export of fibroblast growth factor 1 (FGF1). PloS one\| PubMed ID: 24595027	2014
Efficient production and purification of extracellular domain of human FGFR-Fc fusion proteins from Chinese hamster ovary cells. Protein expression and purification\| PubMed ID: 24727156	2014
Identification of new FGF1 binding partners-Implications for its intracellular function. IUBMB life\| PubMed ID: 26840910	2016
Design and characteristics of cytotoxic fibroblast growth factor 1 conjugate for fibroblast growth factor receptor-targeted cancer therapy. Drug design, development and therapy\| PubMed ID: 27563235	2016
High-Affinity Internalizing Human scFv-Fc Antibody for Targeting FGFR1-Overexpressing Lung Cancer. Molecular cancer research : MCR\| PubMed ID: 28483948	2017
High-Yield Site-Specific Conjugation of Fibroblast Growth Factor 1 with Monomethylauristatin E via Cysteine Flanked by Basic Residues. Bioconjugate chemistry\| PubMed ID: 28598150	2017
The autoinhibitory function of D1 domain of FGFR1 goes beyond the inhibition of ligand binding. The international journal of biochemistry & cell biology\| PubMed ID: 28652212	2017
Antibody-induced dimerization of FGFR1 promotes receptor endocytosis independently of its kinase activity. Scientific reports\| PubMed ID: 28769084	2017
High Affinity Promotes Internalization of Engineered Antibodies Targeting FGFR1. International journal of molecular sciences\| PubMed ID: 29748524	2018
Nanodiamonds as "artificial proteins": Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals. Biomaterials\| PubMed ID: 29879652	2018
Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors. ACS omega\| PubMed ID: 30023704	2017
FGF2 Dual Warhead Conjugate with Monomethyl Auristatin E and α-Amanitin Displays a Cytotoxic Effect towards Cancer Cells Overproducing FGF Receptor 1. International journal of molecular sciences\| PubMed ID: 30029518	2018
Translocation of Exogenous FGF1 and FGF2 Protects the Cell against Apoptosis Independently of Receptor Activation. Journal of molecular biology\| PubMed ID: 30099027	2018
Specific Antibody Fragment Ligand Traps Blocking FGF1 Activity. International journal of molecular sciences\| PubMed ID: 30134556	2018
Targeting Cellular Trafficking of Fibroblast Growth Factor Receptors as a Strategy for Selective Cancer Treatment. Journal of clinical medicine\| PubMed ID: 30577533	2018
Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling. International journal of molecular sciences\| PubMed ID: 31013829	2019
Cross-Talk between Fibroblast Growth Factor Receptors and Other Cell Surface Proteins. Cells\| PubMed ID: 31091809	2019
Differential regulation of fibroblast growth factor receptor 1 trafficking and function by extracellular galectins. Cell communication and signaling : CCS\| PubMed ID: 31208421	2019
Low Stability of Integrin-Binding Deficient Mutant of FGF1 Restricts Its Biological Activity. Cells\| PubMed ID: 31443196	2019
FHF1 is a bona fide fibroblast growth factor that activates cellular signaling in FGFR-dependent manner. Cell communication and signaling : CCS\| PubMed ID: 32357892	2020
Intracellular partners of fibroblast growth factors 1 and 2 - implications for functions. Cytokine & growth factor reviews\| PubMed ID: 32475760	2020
Site-Specific, Stoichiometric-Controlled, PEGylated Conjugates of Fibroblast Growth Factor 2 (FGF2) with Hydrophilic Auristatin Y for Highly Selective Killing of Cancer Cells Overproducing F... Molecular pharmaceutics\| PubMed ID: 32501706	2020
FGFR1 clustering with engineered tetravalent antibody improves the efficiency and modifies the mechanism of receptor internalization. Molecular oncology\| PubMed ID: 32511887	2020
Stable Fibroblast Growth Factor 2 Dimers with High Pro-Survival and Mitogenic Potential. International journal of molecular sciences\| PubMed ID: 32526859	2020