Lorraine V. Kalia

Lorraine V. Kalia

Krembil Research Institute, University Health Network

Affiliated withUniversity Health NetworkUniversity of TorontoUniversity Health Network

Research Area

Biography

Lorraine Kalia received her MD/PhD and neurology residency training at the University of Toronto, Canada. She conducted a postdoctoral research fellowship at Massachusetts General Hospital, USA and a movement disorders fellowship at Toronto Western Hospital, Canada.

Currently, she is an associate professor and clinician-scientist in the Division of Neurology, Department of Medicine at the University of Toronto. She is also a senior scientist at the Krembil Research Institute of the University Health Network. She holds appointments with the University of Toronto’s Tanz Centre for Research in Neurodegenerative Diseases and Department of Laboratory Medicine and Pathobiology.

Her research program focuses on Parkinson’s disease and related movement disorders. She heads a research team focused on elucidating the critical molecular mechanisms responsible for neurodegeneration in Parkinson’s disease and identifying therapeutic agents that can modulate or target these molecular mediators of neurodegeneration. She has received research funding from the Canadian Institutes of Health Research, J. P. Bickell Foundation, Michael J. Fox Foundation for Parkinson's Research, Natural Sciences and Engineering Research Council of Canada, Ontario Brain Institute, Parkinson Canada, Parkinson's UK, and Toronto General & Western Hospital Foundation.

JoVE Journal Publications

ArticleTotal : 1
Year
Semi-Quantitative Determination of Dopaminergic Neuron Density in the Substantia Nigra of Rodent Models using Automated Image Analysis
Publication title

Cited by 6

2021

Other Publications

Article
Year
NMDA receptors in clinical neurology: excitatory times ahead.

The Lancet. Neurology| PubMed ID: 18635022

2008
2011
2012
Pathogenesis-targeted, disease-modifying therapies in Parkinson disease.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics| PubMed ID: 24085420

2014
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 24510904

2014
2015
α-Synuclein and Lewy pathology in Parkinson's disease.

Current opinion in neurology| PubMed ID: 26110807

2015
Disease-modifying strategies for Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society| PubMed ID: 26208210

2015
2016
2016
α-Synuclein and Parkinsonism: Updates and Future Perspectives.

Current neurology and neuroscience reports| PubMed ID: 28324300

2017
2017
Biomarkers for cognitive dysfunction in Parkinson's disease.

Parkinsonism & related disorders| PubMed ID: 28781202

2018
2017
Complex genomic rearrangement in SPG11 due to a DNA replication-based mechanism.

Movement disorders : official journal of the Movement Disorder Society| PubMed ID: 29082553

2017
Is there a role for MR-guided focused ultrasound in Parkinson's disease?

Movement disorders : official journal of the Movement Disorder Society| PubMed ID: 29476631

2018
2018
Tremor in Spinocerebellar Ataxia Type 12.

Movement disorders clinical practice| PubMed ID: 30363887

2014
Parkinsonism due to A53E α-synuclein gene mutation: Clinical, genetic, epigenetic, and biochemical features.

Movement disorders : official journal of the Movement Disorder Society| PubMed ID: 30423204

2018
2019
Deep brain stimulation: potential for neuroprotection.

Annals of clinical and translational neurology| PubMed ID: 30656196

2019
The clinical significance of lower limb tremors.

Parkinsonism & related disorders| PubMed ID: 31201091

2019
2019
2020
2019
2020
2020
Methods for detecting toxic α-synuclein species as a biomarker for Parkinson's disease.

Critical reviews in clinical laboratory sciences| PubMed ID: 32116096

2020
2020
2020
2020
2021
2020
2020
2020
AN INTELLIGENT DIAGNOSIS: SMART SYNDROME.

The American journal of medicine| PubMed ID: 33444593

2021