William J. Janssen

Division of Pulmonary, National Jewish Health

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2021

Other Publications

Article	Year
CD38 plays a dual role in allergen-induced airway hyperresponsiveness. American journal of respiratory cell and molecular biology\| PubMed ID: 18931329	2009
Dyspnea, chest pain, and altered mental status in a 33-year-old carpenter. Chest\| PubMed ID: 18988783	2008
Cigarette smoke impairs clearance of apoptotic cells through oxidant-dependent activation of RhoA. American journal of respiratory and critical care medicine\| PubMed ID: 19264974	2009
TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 19648283	2009
Development and characterization of a lung-protective method of bone marrow transplantation in the mouse. Journal of immunological methods\| PubMed ID: 20347833	2010
Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN-Î³ in a nitric oxide-dependent manner. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20805415	2010
Fas determines differential fates of resident and recruited macrophages during resolution of acute lung injury. American journal of respiratory and critical care medicine\| PubMed ID: 21471090	2011
Cellular regulation of the inflammatory response. Toxicologic pathology\| PubMed ID: 22089838	2012
Macrophages mediate lung inflammation in a mouse model of ischemic acute kidney injury. American journal of physiology. Renal physiology\| PubMed ID: 22114207	2012
Vascular endothelial growth factor enhances macrophage clearance of apoptotic cells. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 22307908	2012
Nrf2 protects human alveolar epithelial cells against injury induced by influenza A virus. Respiratory research\| PubMed ID: 22672594	2012
Increased lymphatic vessel length is associated with the fibroblast reticulum and disease severity in usual interstitial pneumonia and nonspecific interstitial pneumonia. Chest\| PubMed ID: 22797508	2012
The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis. Nature medicine\| PubMed ID: 22820644	2012
Apoptotic cell clearance and fibrotic lung disease. The European respiratory journal\| PubMed ID: 22855466	2012
Defective efferocytosis by alveolar macrophages in IPF patients. Respiratory medicine\| PubMed ID: 22999220	2012
Chest CT features are associated with poorer quality of life in acute lung injury survivors. Critical care medicine\| PubMed ID: 23263616	2013
The fibroproliferative response in acute respiratory distress syndrome: mechanisms and clinical significance. The European respiratory journal\| PubMed ID: 23520315	2014
Alveolar macrophage dysfunction and chronic alcohol use. Time to think about zinc. American journal of respiratory and critical care medicine\| PubMed ID: 24032380	2013
Circulating hematopoietic progenitor cells are decreased in COPD. COPD\| PubMed ID: 24182349	2014
Muc5b is required for airway defence. Nature\| PubMed ID: 24317696	2014
Protein tyrosine phosphatase α mediates profibrotic signaling in lung fibroblasts through TGF-β responsiveness. The American journal of pathology\| PubMed ID: 24650563	2014
Fas ligand-expressing lymphocytes enhance alveolar macrophage apoptosis in the resolution of acute pulmonary inflammation. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 24838751	2014
Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction. Nature communications\| PubMed ID: 25135627	2014
Kinetics of the angiogenic response in lung endothelium following acute inflammatory injury with bleomycin. Experimental lung research\| PubMed ID: 25153689	2014
General parity between trio and pairwise breeding of laboratory mice in static caging. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25381356	2014
Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis. The Journal of allergy and clinical immunology\| PubMed ID: 25497369	2015
The polymeric mucin Muc5ac is required for allergic airway hyperreactivity. Nature communications\| PubMed ID: 25687754	2015
Conceptual approaches to lung injury and repair. Annals of the American Thoracic Society\| PubMed ID: 25830855	2015
Tracheal dysplasia precedes bronchial dysplasia in mouse model of N-nitroso trischloroethylurea induced squamous cell lung cancer. PloS one\| PubMed ID: 25860262	2015
The Causal Role of IL-4 and IL-13 in Schistosoma mansoni Pulmonary Hypertension. American journal of respiratory and critical care medicine\| PubMed ID: 26192556	2015
Flow Cytometric Analysis of Mononuclear Phagocytes in Nondiseased Human Lung and Lung-Draining Lymph Nodes. American journal of respiratory and critical care medicine\| PubMed ID: 26551758	2016
MicroRNA-34a Negatively Regulates Efferocytosis by Tissue Macrophages in Part via SIRT1. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26718338	2016
Mucins and Their Sugars. Critical Mediators of Hyperreactivity and Inflammation. Annals of the American Thoracic Society\| PubMed ID: 27027967	2016
Selective and inducible targeting of CD11b+ mononuclear phagocytes in the murine lung with hCD68-rtTA transgenic systems. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 27190063	2016
Control of lung defence by mucins and macrophages: ancient defence mechanisms with modern functions. The European respiratory journal\| PubMed ID: 27587549	2016
Myeloid Cell Turnover and Clearance. Microbiology spectrum\| PubMed ID: 27837740	2016
Scratching Below the Surface. The New England journal of medicine\| PubMed ID: 27959764	2016
CD73 regulates anti-inflammatory signaling between apoptotic cells and endotoxin-conditioned tissue macrophages. Cell death and differentiation\| PubMed ID: 28060378	2017
Dual RNA-seq reveals viral infections in asthmatic children without respiratory illness which are associated with changes in the airway transcriptome. Genome biology\| PubMed ID: 28103897	2017
Power of Place: Intravascular Superoxide Dismutase for Prevention of Acute Respiratory Distress Syndrome. American journal of respiratory cell and molecular biology\| PubMed ID: 28145771	2017
Three Unique Interstitial Macrophages in the Murine Lung at Steady State. American journal of respiratory cell and molecular biology\| PubMed ID: 28257233	2017
Cell Origin Dictates Programming of Resident versus Recruited Macrophages during Acute Lung Injury. American journal of respiratory cell and molecular biology\| PubMed ID: 28421818	2017
High resolution computed tomography pattern of usual interstitial pneumonia in rheumatoid arthritis-associated interstitial lung disease: Relationship to survival. Respiratory medicine\| PubMed ID: 28427540	2017
A Time- and Compartment-Specific Activation of Lung Macrophages in Hypoxic Pulmonary Hypertension. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 28500078	2017
TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension. Nature communications\| PubMed ID: 28555642	2017
Deletion of c-FLIP from CD11b Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis. American journal of respiratory cell and molecular biology\| PubMed ID: 28850249	2018
Neutrophil transfer of to lung epithelial cells dampens acute lung injury in mice. Science translational medicine\| PubMed ID: 28931657	2017
Phagocytosis of microparticles by alveolar macrophages during acute lung injury requires MerTK. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 28935638	2018
Promoter Specificity and Efficacy in Conditional and Inducible Transgenic Targeting of Lung Macrophages. Frontiers in immunology\| PubMed ID: 29225599	2017
Correction to: Dual RNA-seq reveals viral infections in asthmatic children without respiratory illness which are associated with changes in the airway transcriptome. Genome biology\| PubMed ID: 29636099	2018
Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury. Respiratory research\| PubMed ID: 29855321	2018
Recombinant IFN-β for Postseptic Acute Lung Injury-What's the Mechanism? American journal of respiratory cell and molecular biology\| PubMed ID: 29957050	2018
Modulation of Myeloid Cell Function Using Conditional and Inducible Transgenic Approaches. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29987790	2018
Mouse Models of Viral Infection. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29987803	2018
Cholestenoic acid is a prognostic biomarker in acute respiratory distress syndrome. The Journal of allergy and clinical immunology\| PubMed ID: 30296525	2019
Mucociliary Defense: Emerging Cellular, Molecular, and Animal Models. Annals of the American Thoracic Society\| PubMed ID: 30431350	2018
Single cell RNA sequencing identifies unique inflammatory airspace macrophage subsets. JCI insight\| PubMed ID: 30721157	2019
Redistribution of EC-SOD resolves bleomycin-induced inflammation increased apoptosis of recruited alveolar macrophages. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 31560857	2019
Inflammation via myeloid differentiation primary response gene 88 signaling mediates the fibrotic response to implantable synthetic poly(ethylene glycol) hydrogels. Acta biomaterialia\| PubMed ID: 31568879	2019
Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension. Cardiovascular research\| PubMed ID: 31710666	2020
Inflammation-Induced Alternative Pre-mRNA Splicing in Mouse Alveolar Macrophages. G3 (Bethesda, Md.)\| PubMed ID: 31810980	2020
NF-κB mediates lipopolysaccharide-induced alternative pre-mRNA splicing of in mouse macrophages. The Journal of biological chemistry\| PubMed ID: 32179652	2020
Localization of Macrophages in the Human Lung via Design-based Stereology. American journal of respiratory and critical care medicine\| PubMed ID: 32197050	2020
Cholesterol 25-hydroxylase promotes efferocytosis and resolution of lung inflammation. JCI insight\| PubMed ID: 32343675	2020
Airspace Macrophages and Monocytes Exist in Transcriptionally Distinct Subsets in Healthy Adults. American journal of respiratory and critical care medicine\| PubMed ID: 33079572	2020
Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes. Cell reports\| PubMed ID: 33147458	2020
Disulfide disruption reverses mucus dysfunction in allergic airway disease. Nature communications\| PubMed ID: 33431872	2021