William S. James

James Martin Stem Cell Facility, University of Oxford

Affiliated withUniversity of Oxford

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2021

Other Publications

Article	Year
Interferon-stimulated gene products as regulators of central carbon metabolism. The FEBS journal\| PubMed ID: 33185982	2020
Derivation and characterisation of the human embryonic stem cell line, OxF1. In vitro cellular & developmental biology. Animal\| PubMed ID: 20333479	2010
Episomal transgene expression in pluripotent stem cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21822889	2011
Differentially expressed, variant U1 snRNAs regulate gene expression in human cells. Genome research\| PubMed ID: 23070852	2013
The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4. PloS one\| PubMed ID: 24465876	2014
Physiological characterisation of human iPS-derived dopaminergic neurons. PloS one\| PubMed ID: 24586273	2014
CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells. Experimental hematology\| PubMed ID: 26101162	2015
LRRK2 in peripheral and central nervous system innate immunity: its link to Parkinson's disease. Biochemical Society transactions\| PubMed ID: 28202666	2017
A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response. Stem cell reports\| PubMed ID: 28591653	2017
Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages. Scientific reports\| PubMed ID: 28827786	2017
RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation. Cell death & disease\| PubMed ID: 30250197	2018
Lentiviral gene therapy vector with UCOE stably restores function in iPSC-derived neutrophils of a CDG patient. Matters\| PubMed ID: 31008103	2018
Mechanism of Diol Dehydration by a Promiscuous Radical-SAM Enzyme Homologue of the Antiviral Enzyme Viperin (RSAD2). Chembiochem : a European journal of chemical biology\| PubMed ID: 31951306	2020
Viperin, through its radical-SAM activity, depletes cellular nucleotide pools and interferes with mitochondrial metabolism to inhibit viral replication. FEBS letters\| PubMed ID: 32061099	2020
ddhCTP produced by the radical-SAM activity of RSAD2 (viperin) inhibits the NAD -dependent activity of enzymes to modulate metabolism. FEBS letters\| PubMed ID: 32232843	2020
LRRK2 Is Recruited to Phagosomes and Co-recruits RAB8 and RAB10 in Human Pluripotent Stem Cell-Derived Macrophages. Stem cell reports\| PubMed ID: 32359446	2020
TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages. Alzheimer's research & therapy\| PubMed ID: 33198789	2020
Honing the Double-Edged Sword: Improving Human iPSC-Microglia Models. Frontiers in immunology\| PubMed ID: 33363548	2020