Lars Edvinsson

Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet

Affiliated withGlostrup Research Institute, Rigshospitalet Lund University

Research Area

Biography

Lars Edvinsson has not added Biography.
If you are Lars Edvinsson and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 7	2021

Other Publications

Article	Year
Comparison of the vasodilator responses of isolated human and rat middle meningeal arteries to migraine related compounds. The journal of headache and pain\| PubMed ID: 24754925	2014
CaMKII and MEK1/2 inhibition time-dependently modify inflammatory signaling in rat cerebral arteries during organ culture. Journal of neuroinflammation\| PubMed ID: 24886705	2014
CaMKII inhibition with KN93 attenuates endothelin and serotonin receptor-mediated vasoconstriction and prevents subarachnoid hemorrhage-induced deficits in sensorimotor function. Journal of neuroinflammation\| PubMed ID: 25498987	2014
Similar Adiponectin Levels in Obese Normotensive and Obese Hypertensive Men and No Vasorelaxant Effect of Adiponectin on Human Arteries. Basic & clinical pharmacology & toxicology\| PubMed ID: 26272341	2016
Contractile Changes in the Vasculature After Subchronic Smoking: A Comparison Between Wild Type and Surfactant Protein D Knock-Out Mice. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco\| PubMed ID: 26508395	2016
Experimental inflammation following dural application of complete Freund's adjuvant or inflammatory soup does not alter brain and trigeminal microvascular passage. The journal of headache and pain\| PubMed ID: 26512021	2015
Kynurenic acid modulates experimentally induced inflammation in the trigeminal ganglion. The journal of headache and pain\| PubMed ID: 26627709	2015
Reduced Mechanical Stretch Induces Enhanced Endothelin B Receptor-Mediated Contractility via Activation of Focal Adhesion Kinase and Extracellular Regulated Kinase 1/2 in Cerebral Arteries f... Basic & clinical pharmacology & toxicology\| PubMed ID: 26781487	2016
New insights on pyrimidine signalling within the arterial vasculature - Different roles for P2Y2 and P2Y6 receptors in large and small coronary arteries of the mouse. Journal of molecular and cellular cardiology\| PubMed ID: 26827897	2016
Improved assessment of outcomes following transient global cerebral ischemia in mice. Experimental brain research\| PubMed ID: 26914479	2016
Enhanced Endothelin-1 Mediated Vasoconstriction of the Ophthalmic Artery May Exacerbate Retinal Damage after Transient Global Cerebral Ischemia in Rat. PloS one\| PubMed ID: 27322388	2016
Alterations in the Cerebral Microvascular Proteome Expression Profile After Transient Global Cerebral Ischemia in Rat. Journal of molecular neuroscience : MN\| PubMed ID: 27933490	2017
Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ETB receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat. PloS one\| PubMed ID: 28323857	2017
Distribution of CGRP and its receptor components CLR and RAMP1 in the rat retina. Experimental eye research\| PubMed ID: 28603014	2017
Distribution of CGRP and CGRP receptor components in the rat brain. Cephalalgia : an international journal of headache\| PubMed ID: 28856910	2017
Cerebrovascular gene expression in spontaneously hypertensive rats. PloS one\| PubMed ID: 28880918	2017
Recognizing the role of CGRP and CGRP receptors in migraine and its treatment. Cephalalgia : an international journal of headache\| PubMed ID: 29020807	2017
Board Walk - October 2017. Cephalalgia : an international journal of headache\| PubMed ID: 29039695	2017
A novel multicolor flow-cytometry application for quantitative detection of receptors on vascular smooth muscle cells. PloS one\| PubMed ID: 29084284	2017
Cerebrovascular Gene Expression in Spontaneously Hypertensive Rats After Transient Middle Cerebral Artery Occlusion. Neuroscience\| PubMed ID: 29102661	2017
Perivascular neurotransmitters: Regulation of cerebral blood flow and role in primary headaches. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 29251523	2017
Headache advances in 2017: a new horizon in migraine therapy. The Lancet. Neurology\| PubMed ID: 29263007	2018
Increased endothelin-1-mediated vasoconstriction after organ culture in rat and pig ocular arteries can be suppressed with MEK/ERK1/2 inhibitors. Acta ophthalmologica\| PubMed ID: 29369532	2018
PACAP and its role in primary headaches. The journal of headache and pain\| PubMed ID: 29523978	2018
Vascular and molecular pharmacology of the metabolically stable CGRP analogue, SAX. European journal of pharmacology\| PubMed ID: 29653090	2018
CGRP as the target of new migraine therapies - successful translation from bench to clinic. Nature reviews. Neurology\| PubMed ID: 29691490	2018
Expression of Pituitary Adenylate Cyclase-activating Peptide, Calcitonin Gene-related Peptide and Headache Targets in the Trigeminal Ganglia of Rats and Humans. Neuroscience\| PubMed ID: 30336190	2018
MEK/ERK/1/2 sensitive vascular changes coincide with retinal functional deficit, following transient ophthalmic artery occlusion. Experimental eye research\| PubMed ID: 30439349	2019
CGRP Antibodies as Prophylaxis in Migraine. Cell\| PubMed ID: 30550780	2018
Vascular pathology of large cerebral arteries in experimental subarachnoid hemorrhage: Vasoconstriction, functional CGRP depletion and maintained CGRP sensitivity. European journal of pharmacology\| PubMed ID: 30653947	2019
Role of CGRP in Migraine. Handbook of experimental pharmacology\| PubMed ID: 30725283	2019
Board Walk - July 2019. Cephalalgia : an international journal of headache\| PubMed ID: 31246131	2019
Does inflammation have a role in migraine? Nature reviews. Neurology\| PubMed ID: 31263254	2019
Rimegepant oral disintegrating tablet for migraine. Lancet (London, England)\| PubMed ID: 31311675	2019
The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology. Pharmacology\| PubMed ID: 31484177	2019
C-fibers may modulate adjacent Aδ-fibers through axon-axon CGRP signaling at nodes of Ranvier in the trigeminal system. The journal of headache and pain\| PubMed ID: 31718551	2019
Cellular distribution of PACAP-38 and PACAP receptors in the rat brain: Relation to migraine activated regions. Cephalalgia : an international journal of headache\| PubMed ID: 31810401	2020
Calcitonin Gene-Related Peptide (CGRP) and Cluster Headache. Brain sciences\| PubMed ID: 31935868	2020
The distribution of oxytocin and the oxytocin receptor in rat brain: relation to regions active in migraine. The journal of headache and pain\| PubMed ID: 32028899	2020
Fluorescent Analogues of Human α-Calcitonin Gene-Related Peptide with Potent Vasodilator Activity. International journal of molecular sciences\| PubMed ID: 32079247	2020
Expression of the CGRP Family of Neuropeptides and their Receptors in the Trigeminal Ganglion. Journal of molecular neuroscience : MN\| PubMed ID: 32086679	2020
Serotonin and Neuropeptides in Blood From Episodic and Chronic Migraine and Cluster Headache Patients in Case-Control and Case-Crossover Settings: A Systematic Review and Meta-Analysis. Headache\| PubMed ID: 32293721	2020
The effects of CGRP in vascular tissue - Classical vasodilation, shadowed effects and systemic dilemmas. European journal of pharmacology\| PubMed ID: 32442540	2020
Oxytocin as a regulatory neuropeptide in the trigeminovascular system: Localization, expression and function of oxytocin and oxytocin receptors. Cephalalgia : an international journal of headache\| PubMed ID: 32486908	2020
Differences in pituitary adenylate cyclase-activating peptide and calcitonin gene-related peptide release in the trigeminovascular system. Cephalalgia : an international journal of headache\| PubMed ID: 32486909	2020
Estrogen receptors α, β and GPER in the CNS and trigeminal system - molecular and functional aspects. The journal of headache and pain\| PubMed ID: 33167864	2020
Transcriptome profiling revealed early vascular smooth muscle cell gene activation following focal ischemic stroke in female rats - comparisons with males. BMC genomics\| PubMed ID: 33297959	2020
Oral rimegepant for migraine prevention. Lancet (London, England)\| PubMed ID: 33338436	2021
Identifying New Antimigraine Targets: Lessons from Molecular Biology. Trends in pharmacological sciences\| PubMed ID: 33495027	2021
Myocardial perfusion recovery induced by an α-calcitonin gene-related peptide analogue. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology\| PubMed ID: 34089154	2021