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Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
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Neuroscience
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JoVE Journal Neuroscience
Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

DOI:
10.3791/62567-v

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09:14 min

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June 18, 2021

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, , , ,
1Department of Neurosurgery,Rigshospitalet, 2Department of Clinical Experimental Research,Glostrup Research Institute, Rigshospitalet, 3Department of Clinical Medicine,University of Copenhagen, 4Department of Clinical Sciences, Division of Experimental Vascular Research,Lund University, 5Department of Clinical Neuroscience,Karolinska Institutet

Chapters

  • 00:04Introduction
  • 00:39Intracerebral Pressure (ICP) Probe Preparation and Placement
  • 03:05Placement of the Needle and the Laser‐Doppler Probe
  • 04:49Induction of Subarachnoid Hemorrhage
  • 06:34Recovery and Awakening
  • 07:45Results: Sensorimotor Function and Contractile Sensitivity Following Subarachnoid Hemorrhage
  • 08:46Conclusion

Summary

Automatic Translation

Automatic Translation

Subarachnoid hemorrhage continues to carry a high burden of mortality and morbidity in man. To facilitate further research into the condition and its pathophysiology, a pre-chiasmatic, single injection model is presented.

Tags

Keywords: Subarachnoid HemorrhageExperimental ModelRatICP ProbeLaser-doppler ProbeReproduciblePathophysiologyTherapyDisease Burden

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