John P. Cooke

Division of Cardiovascular Medicine, Stanford University

Research Area

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 19	2009
Publication title Cited by 198	2009
Publication title Cited by 164	2010

Other Publications

Article	Year
Executive Summary: Pivotal Research in Cardiovascular Syndromes in the Elderly. The American journal of geriatric cardiology\| PubMed ID: 11416575	2000
Effect of local delivery of L-arginine on in-stent restenosis in humans. The American journal of cardiology\| PubMed ID: 11835911	2002
Statins have biphasic effects on angiogenesis. Circulation\| PubMed ID: 11839631	2002
Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor. JAMA : the journal of the American Medical Association\| PubMed ID: 11903029	2002
Nitric oxide and angiogenesis. Circulation\| PubMed ID: 11994243	2002
Nicotine accelerates angiogenesis and wound healing in genetically diabetic mice. The American journal of pathology\| PubMed ID: 12107094	2002
Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase. Circulation\| PubMed ID: 12186805	2002
A novel angiogenic pathway mediated by non-neuronal nicotinic acetylcholine receptors. The Journal of clinical investigation\| PubMed ID: 12189247	2002
Homocysteine impairs coronary microvascular dilator function in humans. Journal of the American College of Cardiology\| PubMed ID: 12354427	2002
Does leptin cause vascular disease? Circulation\| PubMed ID: 12370209	2002
Endothelial determinants of dendritic cell adhesion and migration: new implications for vascular diseases. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 12426210	2002
Short polymers of arginine rapidly translocate into vascular cells: effects on nitric oxide synthesis. Circulation journal : official journal of the Japanese Circulation Society\| PubMed ID: 12499624	2002
Flow, NO, and atherogenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12552094	2003
Nicotine strongly activates dendritic cell-mediated adaptive immunity: potential role for progression of atherosclerotic lesions. Circulation\| PubMed ID: 12566374	2003
Nicotine promotes arteriogenesis. Journal of the American College of Cardiology\| PubMed ID: 12575981	2003
NOS inhibition accelerates atherogenesis: reversal by exercise. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 12598230	2003
Cardiac allograft vasculopathy and dysregulation of the NO synthase pathway. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 12649081	2003
Flow-responsive remodeling after angioplasty is enhanced by high cholesterol diet. Prevention with pyrrolidine dithiocarbamate. Atherosclerosis\| PubMed ID: 12801617	2003
A peculiar result and a fanciful hypothesis regarding L-arginine. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 12807714	2003
Nitric oxide inhibition as a mechanism for blood pressure increase during salt loading in normotensive postmenopausal women. Journal of hypertension\| PubMed ID: 12817182	2003
Postgraduate training in vascular medicine: proposed requirements and standards. Vascular medicine (London, England)\| PubMed ID: 12866611	2003
Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial. Circulation\| PubMed ID: 12912807	2003
Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymmetric dimethylarginine. Circulation\| PubMed ID: 12912818	2003
A novel mechanism for pulmonary arterial hypertension? Circulation\| PubMed ID: 14504250	2003
Gender differences in perception of PAD: a pilot study. Vascular medicine (London, England)\| PubMed ID: 14518610	2003
Second hand smoke stimulates tumor angiogenesis and growth. Cancer cell\| PubMed ID: 14522253	2003
Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence. Circulation\| PubMed ID: 14638548	2003
Asymmetric dimethylarginine (ADMA): a key regulator of nitric oxide synthase. Atherosclerosis. Supplements\| PubMed ID: 14664896	2003
NO and angiogenesis. Atherosclerosis. Supplements\| PubMed ID: 14664903	2003
Cytomegalovirus infection impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine in transplant arteriosclerosis. Circulation\| PubMed ID: 14732750	2004
Discordant effects of a soluble VEGF receptor on wound healing and angiogenesis. Gene therapy\| PubMed ID: 14737090	2004
Developmental endothelial locus-1 (Del-1), a novel angiogenic protein: its role in ischemia. Circulation\| PubMed ID: 14981004	2004
Nicotine and angiogenesis: a new paradigm for tobacco-related diseases. Annals of medicine\| PubMed ID: 15000345	2004
Asymmetrical dimethylarginine: the Uber marker? Circulation\| PubMed ID: 15096461	2004
Randomized trial of AT-1015 for treatment of intermittent claudication. A novel 5-hydroxytryptamine antagonist with no evidence of efficacy. Vascular medicine (London, England)\| PubMed ID: 15230484	2004
Isoflavones improve vascular reactivity in post-menopausal women with hypercholesterolemia. Vascular medicine (London, England)\| PubMed ID: 15230485	2004
Predictors of physical function in patients with peripherial arterial disease and claudication. Progress in cardiovascular nursing\| PubMed ID: 15249768	2004
The pivotal role of nitric oxide for vascular health. The Canadian journal of cardiology\| PubMed ID: 15309199	2004
Adenoviral gene transfer with soluble vascular endothelial growth factor receptors impairs angiogenesis and perfusion in a murine model of hindlimb ischemia. Circulation\| PubMed ID: 15477417	2004
Determination of asymmetric dimethylarginine (ADMA) using a novel ELISA assay. Clinical chemistry and laboratory medicine : CCLM / FESCC\| PubMed ID: 15576299	2004
Exercise patterns and cardiovascular fitness of patients with peripheral arterial disease. Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing\| PubMed ID: 15592339	2004
Capillary electrophoretic and micellar electrokinetic separations of asymmetric dimethyl-L-arginine and structurally related amino acids: quantitation in human plasma. Journal of separation science\| PubMed ID: 15638156	2004
Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis. Circulation\| PubMed ID: 15781754	2005
Suboptimal intensity of risk factor modification in PAD. Vascular medicine (London, England)\| PubMed ID: 16013192	2005
Dimethylarginine dimethylaminohydrolase overexpression suppresses graft coronary artery disease. Circulation\| PubMed ID: 16144995	2005
Homocysteine-induced vascular dysregulation is mediated by the NMDA receptor. Vascular medicine (London, England)\| PubMed ID: 16235775	2005
Arginine metabolism, pulmonary hypertension, and sickle cell disease. JAMA : the journal of the American Medical Association\| PubMed ID: 16287950	2005
Abnormal cardiovascular response to exercise in patients with peripheral arterial disease: Implications for management. Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing\| PubMed ID: 16326331	2005
A pilot study of L-arginine supplementation on functional capacity in peripheral arterial disease. Vascular medicine (London, England)\| PubMed ID: 16444855	2005
Vascular compliance versus flow-mediated vasodilation: correlation with cardiovascular risk factors. Vascular medicine (London, England)\| PubMed ID: 16444856	2005
Mechanisms of Raynaud's disease. Vascular medicine (London, England)\| PubMed ID: 16444858	2005
ADMA: an emerging cardiovascular risk factor. Vascular medicine (London, England)\| PubMed ID: 16444862	2005
ADMA: its role in vascular disease. Vascular medicine (London, England)\| PubMed ID: 16444864	2005
Insulin resistance: potential role of the endogenous nitric oxide synthase inhibitor ADMA. Vascular medicine (London, England)\| PubMed ID: 16444867	2005
Re: The American "board" of vascular medicine: questions and concerns. Journal of vascular and interventional radiology : JVIR\| PubMed ID: 16687766	2006
Symmetric dimethylarginine (SDMA) as endogenous marker of renal function--a meta-analysis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 16766542	2006
ADMA increases arterial stiffness and decreases cerebral blood flow in humans. Stroke; a journal of cerebral circulation\| PubMed ID: 16809568	2006
Psychophysiological and cortisol responses to psychological stress in depressed and nondepressed older men and women with elevated cardiovascular disease risk. Psychosomatic medicine\| PubMed ID: 16868262	2006
Letter by Kielstein et al regarding article, "Renal function as a predictor of outcome in a broad spectrum of patients with heart failure". Circulation\| PubMed ID: 16894045	2006
Acute rejection and cardiac allograft vascular disease is reduced by suppression of subclinical cytomegalovirus infection. Transplantation\| PubMed ID: 16906040	2006
T-cell immunity to subclinical cytomegalovirus infection reduces cardiac allograft disease. Circulation\| PubMed ID: 17015794	2006
A central role for nicotinic cholinergic regulation of growth factor-induced endothelial cell migration. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 17082486	2007
Microenvironmental VEGF distribution is critical for stable and functional vessel growth in ischemia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17095533	2006
Endothelial progenitor cells participate in nicotine-mediated angiogenesis. Journal of the American College of Cardiology\| PubMed ID: 17174197	2006
Should we measure asymmetric dimethylarginine in patients with coronary artery disease? Clinical chemistry\| PubMed ID: 17259245	2007
Nonbone marrow-derived circulating progenitor cells contribute to postnatal neovascularization following tissue ischemia. Circulation research\| PubMed ID: 17272807	2007
Limb hemodynamics are not predictive of functional capacity in patients with PAD. Vascular medicine (London, England)\| PubMed ID: 17288121	2006
SVMB presidential address. The time has come for vascular medicine. Vascular medicine (London, England)\| PubMed ID: 17288126	2006
Dimethylarginine dimethylaminohydrolase promotes endothelial repair after vascular injury. Journal of the American College of Cardiology\| PubMed ID: 17349891	2007
Angiogenesis and the role of the endothelial nicotinic acetylcholine receptor. Life sciences\| PubMed ID: 17383685	2007
NOx and ADMA changes with focal ischemia, amelioration with the chaperonin GroEL. Neuroscience letters\| PubMed ID: 17398004	2007
[Coronary allograft vasculopathy: pathophysiological interaction between the immune system, infections and metabolic syndrome]. Giornale italiano di cardiologia (2006)\| PubMed ID: 17402351	2007
Frequent occult infection with Cytomegalovirus in cardiac transplant recipients despite antiviral prophylaxis. Journal of clinical microbiology\| PubMed ID: 17409205	2007
Changes in coronary arterial dimensions early after cardiac transplantation. Transplantation\| PubMed ID: 17414701	2007
Asymmetric dimethyl-arginine and coronary artery calcification in young adults entering middle age: the CARDIA Study. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology\| PubMed ID: 17446800	2007
A novel bioluminescent tumor model of human renal cancer cell lines: an in vitro and in vivo characterization. The Journal of urology\| PubMed ID: 17509355	2007
Asymmetric dimethyl L-arginine (ADMA) is a critical regulator of myocardial reperfusion injury. Cardiovascular research\| PubMed ID: 17559823	2007
L-arginine supplementation in peripheral arterial disease: no benefit and possible harm. Circulation\| PubMed ID: 17592080	2007
Genetic susceptibility to peripheral arterial disease: a dark corner in vascular biology. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 17656669	2007
Beta2-microglobulin as a biomarker in peripheral arterial disease: proteomic profiling and clinical studies. Circulation\| PubMed ID: 17724262	2007
Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. Circulation\| PubMed ID: 17846325	2007
Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation. Stroke; a journal of cerebral circulation\| PubMed ID: 18063827	2008
Task force 11: training in vascular medicine and peripheral vascular catheter-based interventions endorsed by the Society for Cardiovascular Angiography and Interventions and the Society for... Journal of the American College of Cardiology\| PubMed ID: 18206760	2008
Dimethylarginine dimethylaminohydrolase overexpression enhances insulin sensitivity. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 18239148	2008
Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: modulation by sirolimus. Transplantation\| PubMed ID: 18360263	2008
Mecamylamine suppresses Basal and nicotine-stimulated choroidal neovascularization. Investigative ophthalmology & visual science\| PubMed ID: 18385094	2008
Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 18567702	2008
Critical determinants of limb ischemia. Journal of the American College of Cardiology\| PubMed ID: 18652949	2008
A biomarker panel for peripheral arterial disease. Vascular medicine (London, England)\| PubMed ID: 18687758	2008
Two cardiovascular risk factors in one? Homocysteine and its relation to glomerular filtration rate. A meta-analysis of 41 studies with 27,000 participants. Kidney & blood pressure research\| PubMed ID: 18689992	2008
Letter by Stuehlinger et al regarding article, "Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock ... Circulation\| PubMed ID: 18765383	2008
Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. The Journal of cell biology\| PubMed ID: 19139264	2009
Endothelial nicotinic acetylcholine receptors and angiogenesis. Trends in cardiovascular medicine\| PubMed ID: 19232953	2008
Does improving mood in depressed patients alter factors that may affect cardiovascular disease risk? Journal of psychiatric research\| PubMed ID: 19577757	2009
Cholinergic modulation of angiogenesis: role of the 7 nicotinic acetylcholine receptor. Journal of cellular biochemistry\| PubMed ID: 19623583	2009
Hypercholesterolemia impairs exercise capacity in mice. Vascular medicine (London, England)\| PubMed ID: 19651675	2009
Extensive characterization of the human DDAH1 transgenic mice. Pharmacological research : the official journal of the Italian Pharmacological Society\| PubMed ID: 19666120	2009
Cell-free production of transducible transcription factors for nuclear reprogramming. Biotechnology and bioengineering\| PubMed ID: 19718703	2009
nAChRs mediate human embryonic stem cell-derived endothelial cells: proliferation, apoptosis, and angiogenesis. PloS one\| PubMed ID: 19753305	2009
Chronic exposure to nicotine impairs cholinergic angiogenesis. Vascular medicine (London, England)\| PubMed ID: 19778953	2010
Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia. Circulation research\| PubMed ID: 20019334	2010
Role of nitric oxide signaling in endothelial differentiation of embryonic stem cells. Stem cells and development\| PubMed ID: 20064011	2010
Relationship of asymmetric dimethylarginine and homocysteine to vascular aging in systemic lupus erythematosus patients. Arthritis and rheumatism\| PubMed ID: 20155836	2010
Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 20167654	2010
Topical mecamylamine for diabetic macular edema. American journal of ophthalmology\| PubMed ID: 20189159	2010
DDAH: a target for vascular therapy? Vascular medicine (London, England)\| PubMed ID: 20385710	2010
Biomarkers of peripheral arterial disease. Journal of the American College of Cardiology\| PubMed ID: 20447524	2010
Asymmetric dimethylarginine correlates with measures of disease severity, major adverse cardiovascular events and all-cause mortality in patients with peripheral arterial disease. Vascular medicine (London, England)\| PubMed ID: 20484311	2010
A matrix micropatterning platform for cell localization and stem cell fate determination. Acta biomaterialia\| PubMed ID: 20601236	2010
Stem cell therapy for vascular regeneration: adult, embryonic, and induced pluripotent stem cells. Circulation\| PubMed ID: 20679581	2010
The emerging role of the thioredoxin system in angiogenesis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 20798378	2010
Cholinergic activation of hematopoietic stem cells: role in tobacco-related disease? Vascular medicine (London, England)\| PubMed ID: 20926497	2010
Cerebral autoregulation in the vertebral and middle cerebral arteries during combine head upright tilt and lower body negative pressure in healthy humans. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 21096171	2010
Sex differences in the prevalence of peripheral artery disease in patients undergoing coronary catheterization. Vascular medicine (London, England)\| PubMed ID: 21183651	2010
MicroRNA and mechanisms of impaired angiogenesis in diabetes mellitus. Circulation\| PubMed ID: 21220736	2011
The role of nicotine in the pathogenesis of atherosclerosis. Atherosclerosis\| PubMed ID: 21345436	2011
Dietary nitrate, nitric oxide, and restenosis. The Journal of clinical investigation\| PubMed ID: 21436578	2011
Identification and classification of acute cardiac rejection by intragraft transcriptional profiling. Circulation\| PubMed ID: 21555702	2011
Low lifetime recreational activity is a risk factor for peripheral arterial disease. Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter\| PubMed ID: 21664093	2011
DDAH says NO to ADMA. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21677286	2011
Two decades of progress in vascular medicine. The American journal of medicine\| PubMed ID: 21683936	2011
Solubility partner IF2 Domain I enables high yield synthesis of transducible transcription factors in Escherichia coli. Protein expression and purification\| PubMed ID: 21757009	2011
Increased nitric oxide availability attenuates high fat diet metabolic alterations and gene expression associated with insulin resistance. Cardiovascular diabetology\| PubMed ID: 21781316	2011
Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21836062	2011
Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin f(2Î±) impairs endothelial function in renovascular hypertensive rats. Antioxidants & redox signaling\| PubMed ID: 21951274	2012
Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circulation. Cardiovascular genetics\| PubMed ID: 22199011	2012
Lymphangiogenesis: A Potential New Therapy for Lymphedema? Circulation\| PubMed ID: 22275500	2012