Atsushi Enomoto

Department of Pathology, Nagoya University Graduate School of Medicine

Affiliated withNagoya University Graduate School of Medicine

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2021

Other Publications

Article	Year
Activation of c-Jun amino-terminal kinase by GDNF induces G2/M cell cycle delay linked with actin reorganization. Genes to cells : devoted to molecular & cellular mechanisms\| PubMed ID: 15966897	2005
GDNF-inducible zinc finger protein 1 is a sequence-specific transcriptional repressor that binds to the HOXA10 gene regulatory region. Nucleic acids research\| PubMed ID: 16049025	2005
Akt/PKB regulates actin organization and cell motility via Girdin/APE. Developmental cell\| PubMed ID: 16139227	2005
RET receptor signaling: dysfunction in thyroid cancer and Hirschsprung's disease. Pathology international\| PubMed ID: 16634961	2006
Dok-4 regulates GDNF-dependent neurite outgrowth through downstream activation of Rap1 and mitogen-activated protein kinase. Journal of cell science\| PubMed ID: 16820412	2006
Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells. Development (Cambridge, England)\| PubMed ID: 17050626	2006
Girdin, a novel actin-binding protein, and its family of proteins possess versatile functions in the Akt and Wnt signaling pathways. Annals of the New York Academy of Sciences\| PubMed ID: 17185515	2006
Sprouty2 regulates growth and differentiation of human neuroblastoma cells through RET tyrosine kinase. Cancer science\| PubMed ID: 17388787	2007
Nucleolin modulates the subcellular localization of GDNF-inducible zinc finger protein 1 and its roles in transcription and cell proliferation. Experimental cell research\| PubMed ID: 17674968	2007
Roles of organic anion transporters in the progression of chronic renal failure. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy\| PubMed ID: 17976081	2007
A novel GDNF-inducible gene, BMZF3, encodes a transcriptional repressor associated with KAP-1. Biochemical and biophysical research communications\| PubMed ID: 18060868	2008
Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin. Nature cell biology\| PubMed ID: 18264090	2008
An actin-binding protein Girdin regulates the motility of breast cancer cells. Cancer research\| PubMed ID: 18316593	2008
GDNF-mediated signaling via RET tyrosine 1062 is essential for maintenance of spermatogonial stem cells. Genes to cells : devoted to molecular & cellular mechanisms\| PubMed ID: 18363967	2008
[Coordination of actin cytoskeleton and membrane transport in cell migration]. Seikagaku. The Journal of Japanese Biochemical Society\| PubMed ID: 18411793	2008
CD109 expression in basal-like breast carcinoma. Pathology international\| PubMed ID: 18429827	2008
Cell biology of the movement of breast cancer cells: intracellular signalling and the actin cytoskeleton. Cancer letters\| PubMed ID: 19303207	2009
Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress. Cancer research\| PubMed ID: 19351825	2009
Adiponectin promotes migration activities of endothelial progenitor cells via Cdc42/Rac1. FEBS letters\| PubMed ID: 19596003	2009
Expression of Ret finger protein correlates with outcomes in endometrial cancer. Cancer science\| PubMed ID: 19650860	2009
Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. Neuron\| PubMed ID: 19778507	2009
Girding for migratory cues: roles of the Akt substrate Girdin in cancer progression and angiogenesis. Cancer science\| PubMed ID: 20132219	2010
Analysis of DOK-6 function in downstream signaling of RET in human neuroblastoma cells. Cancer science\| PubMed ID: 20210798	2010
Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NF-kappaB activation. American journal of nephrology\| PubMed ID: 20389059	2010
Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate. American journal of physiology. Cell physiology\| PubMed ID: 20720180	2010
Loss of Sprouty2 partially rescues renal hypoplasia and stomach hypoganglionosis but not intestinal aganglionosis in Ret Y1062F mutant mice. Developmental biology\| PubMed ID: 21070764	2011
Protective role of Gipie, a Girdin family protein, in endoplasmic reticulum stress responses in endothelial cells. Molecular biology of the cell\| PubMed ID: 21289099	2011
Analysis of glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 expression in human diseased kidney. Human pathology\| PubMed ID: 21292309	2011
Indoxyl sulfate downregulates renal expression of Klotho through production of ROS and activation of nuclear factor-ĸB. American journal of nephrology\| PubMed ID: 21389697	2011
[Roles of DISC1-interacting protein Girdin in postnatal development and adult neurogenesis in the dentate gyrus]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology\| PubMed ID: 21409841	2011
The actin-binding protein Girdin and its Akt-mediated phosphorylation regulate neointima formation after vascular injury. Circulation research\| PubMed ID: 21415395	2011
NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via Disrupted-In-Schizophrenia 1 (DISC1). Journal of neurochemistry\| PubMed ID: 21517847	2011
Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21632933	2011
NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells. American journal of physiology. Cell physiology\| PubMed ID: 21832251	2011
Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse. Human molecular genetics\| PubMed ID: 21903668	2011
Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress. American journal of physiology. Cell physiology\| PubMed ID: 22555846	2012
Involvement of Girdin in the determination of cell polarity during cell migration. PloS one\| PubMed ID: 22574214	2012
The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility. Nature communications\| PubMed ID: 22643886	2012
Epidermal hyperplasia and appendage abnormalities in mice lacking CD109. The American journal of pathology\| PubMed ID: 22846721	2012
Similar phenotypes of Girdin germ-line and conditional knockout mice indicate a crucial role for Girdin in the nestin lineage. Biochemical and biophysical research communications\| PubMed ID: 22974978	2012
Girdin and its phosphorylation dynamically regulate neonatal vascular development and pathological neovascularization in the retina. The American journal of pathology\| PubMed ID: 23195430	2013
Expression of RET finger protein predicts chemoresistance in epithelial ovarian cancer. Cancer medicine\| PubMed ID: 23342271	2012
Metamorphosis of mesothelial cells with active horizontal motility in tissue culture. Scientific reports\| PubMed ID: 23359855	2013
The REV7 subunit of DNA polymerase ζ is essential for primordial germ cell maintenance in the mouse. The Journal of biological chemistry\| PubMed ID: 23463509	2013
Indoxyl sulfate promotes cardiac fibrosis with enhanced oxidative stress in hypertensive rats. Life sciences\| PubMed ID: 23702423	2013
Role of Girdin in intimal hyperplasia in vein grafts and efficacy of atelocollagen-mediated application of small interfering RNA for vein graft failure. Journal of vascular surgery\| PubMed ID: 23948670	2014
Degeneration of retinal on bipolar cells induced by serum including autoantibody against TRPM1 in mouse model of paraneoplastic retinopathy. PloS one\| PubMed ID: 24282602	2013
Suppression of REV7 enhances cisplatin sensitivity in ovarian clear cell carcinoma cells. Cancer science\| PubMed ID: 24597627	2014
Indoxyl sulfate-induced activation of (pro)renin receptor is involved in expression of TGF-β1 and α-smooth muscle actin in proximal tubular cells. Endocrinology\| PubMed ID: 24601883	2014
High glucose impairs the proliferation and increases the apoptosis of endothelial progenitor cells by suppression of Akt. Journal of diabetes investigation\| PubMed ID: 24843496	2011
Regulation of cargo-selective endocytosis by dynamin 2 GTPase-activating protein girdin. The EMBO journal\| PubMed ID: 25061227	2014
Identification of the novel autoantigen candidate Rab GDP dissociation inhibitor alpha in isolated adrenocorticotropin deficiency. Endocrine journal\| PubMed ID: 25346144	2015
Girdin phosphorylation is crucial for synaptic plasticity and memory: a potential role in the interaction of BDNF/TrkB/Akt signaling with NMDA receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 25378165	2014
Girdin is phosphorylated on tyrosine 1798 when associated with structures required for migration. Biochemical and biophysical research communications\| PubMed ID: 25707853	2015
Akt-Girdin signaling in cancer-associated fibroblasts contributes to tumor progression. Cancer research\| PubMed ID: 25732845	2015
New endoplasmic reticulum stress regulator, Gipie, regulates the survival of vascular smooth muscle cells and the neointima formation after vascular injury. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 25792451	2015
Cytokinetic Failure-induced Tetraploidy Develops into Aneuploidy, Triggering Skin Aging in Phosphovimentin-deficient Mice. The Journal of biological chemistry\| PubMed ID: 25847236	2015
Girdin/GIV regulates transendothelial permeability by controlling VE-cadherin trafficking through the small GTPase, R-Ras. Biochemical and biophysical research communications\| PubMed ID: 25869066	2015
Rabphilin-3A as a Targeted Autoantigen in Lymphocytic Infundibulo-neurohypophysitis. The Journal of clinical endocrinology and metabolism\| PubMed ID: 25919460	2015
Potential involvement of kinesin-1 in the regulation of subcellular localization of Girdin. Biochemical and biophysical research communications\| PubMed ID: 26072378	2015
Akt-dependent Girdin phosphorylation regulates repair processes after acute myocardial infarction. Journal of molecular and cellular cardiology\| PubMed ID: 26393439	2015
Role for Daple in non-canonical Wnt signaling during gastric cancer invasion and metastasis. Cancer science\| PubMed ID: 26577606	2016
Akt-Girdin as oncotarget. Oncoscience\| PubMed ID: 26682257	2015
Collective invasion of cancer: Perspectives from pathology and development. Pathology international\| PubMed ID: 26897041	2016
Identification of Meflin as a Potential Marker for Mesenchymal Stromal Cells. Scientific reports\| PubMed ID: 26924503	2016
Ectodermal Dysplasia: Management of Knife-Edged Irregular Ridge and Its Rehabilitation with Hybrid Implant Prosthesis. Journal of clinical and diagnostic research : JCDR\| PubMed ID: 27437373	2016
Clinicopathological and Immunohistochemical Characteristics of Verruciform Xanthoma of the Lower Gingiva: A Case Report. Journal of clinical and diagnostic research : JCDR\| PubMed ID: 27504422	2016
Desmin phosphorylation by Cdk1 is required for efficient separation of desmin intermediate filaments in mitosis and detected in murine embryonic/newborn muscle and human rhabdomyosarcoma tis... Biochemical and biophysical research communications\| PubMed ID: 27565725	2016
High-fat diet feeding promotes stemness and precancerous changes in murine gastric mucosa mediated by leptin receptor signaling pathway. Archives of biochemistry and biophysics\| PubMed ID: 27693038	2016
Suppression of skin tumorigenesis in CD109-deficient mice. Oncotarget\| PubMed ID: 27756876	2016
Well-differentiated neuroendocrine tumor of the breast with extensive lymphatic and vascular infiltration. Pathology international\| PubMed ID: 27862661	2016
A Case of Sialolithiasis in a Minor Salivary Gland of the Buccal Mucosa. Journal of clinical and diagnostic research : JCDR\| PubMed ID: 28050512	2016
Tyrosine Phosphorylation of an Actin-Binding Protein Girdin Specifically Marks Tuft Cells in Human and Mouse Gut. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 28375676	2017
Significance of low mTORC1 activity in defining the characteristics of brain tumor stem cells. Neuro-oncology\| PubMed ID: 28453744	2017
Significance of perivascular tumour cells defined by CD109 expression in progression of glioma. The Journal of pathology\| PubMed ID: 28888050	2017
ASC amino acid transporter 2, defined by enzyme-mediated activation of radical sources, enhances malignancy of GD2-positive small-cell lung cancer. Cancer science\| PubMed ID: 29151270	2018
Cullin-associated NEDD8-dissociated protein 1, a novel interactor of rabphilin-3A, deubiquitylates rabphilin-3A and regulates arginine vasopressin secretion in PC12 cells. Endocrine journal\| PubMed ID: 29367474	2018
Critical role of rabphilin-3A in the pathophysiology of experimental lymphocytic neurohypophysitis. The Journal of pathology\| PubMed ID: 29377134	2018
Development of a method to preliminarily embed tissue samples using low melting temperature fish gelatin before sectioning: A technical note. Pathology international\| PubMed ID: 29465759	2018
Regulation of keratin 5/14 intermediate filaments by CDK1, Aurora-B, and Rho-kinase. Biochemical and biophysical research communications\| PubMed ID: 29518391	2018
Negative regulation of amino acid signaling by MAPK-regulated 4F2hc/Girdin complex. PLoS biology\| PubMed ID: 29538402	2018
Essential Role of Linx/Islr2 in the Development of the Forebrain Anterior Commissure. Scientific reports\| PubMed ID: 29739947	2018
CD109 deficiency induces osteopenia with an osteoporosis-like phenotype in vivo. Genes to cells : devoted to molecular & cellular mechanisms\| PubMed ID: 29767469	2018
Trefoil factor 1 inhibits epithelial-mesenchymal transition of pancreatic intraepithelial neoplasm. The Journal of clinical investigation\| PubMed ID: 29809170	2018
Girdin/GIV regulates collective cancer cell migration by controlling cell adhesion and cytoskeletal organization. Cancer science\| PubMed ID: 30194792	2018
A rare pseudo tumour in the extraembryonic coelom in first trimester of pregnancy: ultrasound and pathology. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology\| PubMed ID: 30406702	2019
Chemerin promotes angiogenesis in vivo. Physiological reports\| PubMed ID: 30588761	2018
Cancer-associated fibroblasts in gastrointestinal cancer. Nature reviews. Gastroenterology & hepatology\| PubMed ID: 30778141	2019
Dephosphorylation of Girdin by PP2A inhibits breast cancer metastasis. Biochemical and biophysical research communications\| PubMed ID: 30935690	2019
CD109: a multifunctional GPI-anchored protein with key roles in tumor progression and physiological homeostasis. Pathology international\| PubMed ID: 31219232	2019
Roles of the Mesenchymal Stromal/Stem Cell Marker Meflin in Cardiac Tissue Repair and the Development of Diastolic Dysfunction. Circulation research\| PubMed ID: 31221024	2019
TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets. The Journal of clinical investigation\| PubMed ID: 31355778	2019
Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis. Cancer research\| PubMed ID: 31439548	2019
Cancer-associated fibroblasts that restrain cancer progression: Hypotheses and perspectives. Cancer science\| PubMed ID: 32060987	2020
Connective tissue growth factor produced by cancer‑associated fibroblasts correlates with poor prognosis in epithelioid malignant pleural mesothelioma. Oncology reports\| PubMed ID: 32705221	2020
Complex roles of the actin-binding protein Girdin/GIV in DNA damage-induced apoptosis of cancer cells. Cancer science\| PubMed ID: 32875699	2020
The Daple-CK1ε complex regulates Dvl2 phosphorylation and canonical Wnt signaling. Biochemical and biophysical research communications\| PubMed ID: 32888647	2020
Vascular PDGFR-alpha protects against BBB dysfunction after stroke in mice. Angiogenesis\| PubMed ID: 32918673	2021
CD109 regulates in vivo tumor invasion in lung adenocarcinoma through TGF-β signaling. Cancer science\| PubMed ID: 33007133	2020
The Balance of Stromal BMP Signaling Mediated by GREM1 and ISLR Drives Colorectal Carcinogenesis. Gastroenterology\| PubMed ID: 33197448	2021
Oncolytic activity of naturally attenuated herpes-simplex virus HF10 against an immunocompetent model of oral carcinoma. Molecular therapy oncolytics\| PubMed ID: 33665360	2021
Meflin defines mesenchymal stem cells and/or their early progenitors with multilineage differentiation capacity. Genes to cells : devoted to molecular & cellular mechanisms\| PubMed ID: 33960573	2021
CD4 T cells are essential for the development of destructive thyroiditis induced by anti-PD-1 antibody in thyroglobulin-immunized mice. Science translational medicine\| PubMed ID: 33980577	2021
The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis-associated liver tumors in a novel murine model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 34029949	2021
A new primate model of hypophyseal dysfunction. Scientific reports\| PubMed ID: 34031474	2021
Fibroblasts positive for meflin have anti-fibrotic property in pulmonary fibrosis. The European respiratory journal\| PubMed ID: 34049947	2021
The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia. Current biology : CB\| PubMed ID: 34087104	2021
Size and surface modification of silica nanoparticles affect the severity of lung toxicity by modulating endosomal ROS generation in macrophages. Particle and fibre toxicology\| PubMed ID: 34134732	2021
The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses. Development (Cambridge, England)\| PubMed ID: 34184027	2021
Newly Established Patient-derived Organoid Model of Intracranial Meningioma. Neuro-oncology\| PubMed ID: 34214169	2021