Kenju Shimomura

Department of Bioregulation and Pharmacological Medicine, Fukushima Medical University

Affiliated withFukushima Medical University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2021

Other Publications

Article	Year
Chronic phencyclidine treatment induces long-lasting glutamatergic activation of VTA dopamine neurons. Neuroscience letters\| PubMed ID: 24525246	2014
Oxytocinergic circuit from paraventricular and supraoptic nuclei to arcuate POMC neurons in hypothalamus. FEBS letters\| PubMed ID: 25448678	2014
Water intake disorder in a DEND syndrome afflicted patient with R50P mutation. Endocrine journal\| PubMed ID: 25739471	2015
Central action of ELABELA reduces food intake and activates arginine vasopressin and corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus. Neuroreport\| PubMed ID: 26237243	2015
Projections from a single NUCB2/nesfatin-1 neuron in the paraventricular nucleus to different brain regions involved in feeding. Brain structure & function\| PubMed ID: 26639940	2016
Islet Insulin Secretion Measurements in the Mouse. Current protocols in mouse biology\| PubMed ID: 27584553	2016
Orexin action on oxytocin neurons in the paraventricular nucleus of the hypothalamus. Neuroreport\| PubMed ID: 28338525	2017
Non-alcoholic Fatty Liver Disease Is a Risk Factor for Type 2 Diabetes in Middle-aged Japanese Men and Women. Internal medicine (Tokyo, Japan)\| PubMed ID: 28381741	2017
Nesfatin-1 inhibits voltage gated K channels in pancreatic beta cells. Peptides\| PubMed ID: 28697955	2017
Impact of sex, fat distribution and initial body weight on oxytocin's body weight regulation. Scientific reports\| PubMed ID: 28819236	2017
K Channel Mutations and Neonatal Diabetes. Internal medicine (Tokyo, Japan)\| PubMed ID: 28824061	2017
Action Selection and Flexible Switching Controlled by the Intralaminar Thalamic Neurons. Cell reports\| PubMed ID: 29490273	2018
The Anorexigenic Neural Pathways of Oxytocin and Their Clinical Implication. Neuroendocrinology\| PubMed ID: 29660735	2018
Update of green tea interactions with cardiovascular drugs and putative mechanisms. Journal of food and drug analysis\| PubMed ID: 29703388	2018
Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans? European journal of clinical pharmacology\| PubMed ID: 29770840	2018
Memantine has no effect on K channels in pancreatic β cells. BMC research notes\| PubMed ID: 30144824	2018
The effect of avertin anesthesia and a mixture of three types of anesthetic agents on food intakeand body weight in high fat-induced obese maleand female mice. Experimental animals\| PubMed ID: 30210091	2019
Poland syndrome accompanied by internal iliac artery supply disruption sequence: a case report. Journal of medical case reports\| PubMed ID: 30360754	2018
Excitability of oxytocin neurons in paraventricular nucleus is regulated by voltage-gated potassium channels Kv4.2 and Kv4.3. Bioscience, biotechnology, and biochemistry\| PubMed ID: 30392457	2019
Structural basis of different substrate preferences of two old yellow enzymes from yeasts in the asymmetric reduction of enone compounds. Bioscience, biotechnology, and biochemistry\| PubMed ID: 30445889	2019
Impact of dapagliflozin, an SGLT2 inhibitor, on serum levels of soluble dipeptidyl peptidase-4 in patients with type 2 diabetes and non-alcoholic fatty liver disease. International journal of clinical practice\| PubMed ID: 30810254	2019
LGR4 is essential for R-spondin1-mediated suppression of food intake via pro-opiomelanocortin. Bioscience, biotechnology, and biochemistry\| PubMed ID: 30916623	2019
Noninvasive continuous blood pressure monitoring using microelectromechanical system technology. Blood pressure monitoring\| PubMed ID: 30998555	2019
MLH1 germline mutation associated with Lynch syndrome in a family followed for more than 45 years. BMC medical genetics\| PubMed ID: 31046708	2019
An In Vitro System for Evaluating Molecular Targeted Drugs Using Lung Patient-Derived Tumor Organoids. Cells\| PubMed ID: 31137590	2019
The undeveloped properties of GABA neurons in the ventral tegmental area promote energy intake for growth in juvenile rats. Scientific reports\| PubMed ID: 31413349	2019
The SGLT2 Inhibitor Canagliflozin Prevents Carcinogenesis in a Mouse Model of Diabetes and Non-Alcoholic Steatohepatitis-Related Hepatocarcinogenesis: Association with SGLT2 Expression in He... International journal of molecular sciences\| PubMed ID: 31652578	2019
Association between cognitive impairment patient with solid cancer and insulin resistance. BMC research notes\| PubMed ID: 31661025	2019
The hypothalamus to brainstem circuit suppresses late-onset body weight gain. Scientific reports\| PubMed ID: 31798010	2019
Cluster of differentiation 8 and programmed cell death ligand 1 expression in triple-negative breast cancer combined with autosomal dominant polycystic kidney disease and tuberous sclerosis ... Journal of medical case reports\| PubMed ID: 31870441	2019
TAK-242, a specific inhibitor of Toll-like receptor 4 signalling, prevents endotoxemia-induced skeletal muscle wasting in mice. Scientific reports\| PubMed ID: 31959927	2020
Atorvastatin-Green Tea Interaction: Possible Mechanisms are Complicated, But Clinical Relevance is Not? European journal of drug metabolism and pharmacokinetics\| PubMed ID: 32297048	2020
Oral oxytocin delivery with proton pump inhibitor pretreatment decreases food intake. Peptides\| PubMed ID: 32298773	2020
Effects of single green tea ingestion on pharmacokinetics of nadolol in healthy volunteers. British journal of clinical pharmacology\| PubMed ID: 32320490	2020
Goshajinkigan, a Traditional Japanese Medicine, Suppresses Voltage-Gated Sodium Channel Nav1.4 Currents in C2C12 Cells. BioResearch open access\| PubMed ID: 32368413	2020
Early life high-fat diet exposure evokes normal weight obesity. Nutrition & metabolism\| PubMed ID: 32595758	2020
Single administration of resveratrol improves social behavior in adult mouse models of autism spectrum disorder. Bioscience, biotechnology, and biochemistry\| PubMed ID: 32698690	2020
Impact of Green Tea Catechin Ingestion on the Pharmacokinetics of Lisinopril in Healthy Volunteers. Clinical and translational science\| PubMed ID: 33048477	2021
Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes. The Journal of clinical investigation\| PubMed ID: 33196462	2020
Detection of NUCB2/nesfatin-1 in cerebrospinal fluid of multiple sclerosis patients. Aging\| PubMed ID: 33318307	2020
Targeting oxytocin receptor (Oxtr)-expressing neurons in the lateral septum to restore social novelty in autism spectrum disorder mouse models. Scientific reports\| PubMed ID: 33335150	2020
Opening of Intermediate Conductance Ca-Activated K Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 33376149	2021
Urinary Excretion of Nadolol as a Possible In Vivo Probe for Drug Interactions Involving P-Glycoprotein. Journal of clinical pharmacology\| PubMed ID: 33387374	2021
Structure based analysis of K channel with a DEND syndrome mutation in murine skeletal muscle. Scientific reports\| PubMed ID: 33758250	2021
Evaluation of organ glucose metabolism by F-FDG accumulation with insulin loading in aged mice compared with young normal mice. Scientific reports\| PubMed ID: 33795778	2021
Construction of patient-derived tumor models to evaluate anticancer agents and cancer immunotherapy. Oncology letters\| PubMed ID: 33841567	2021
Evaluation of Effect of Ninjin'yoeito on Regional Brain Glucose Metabolism by F-FDG Autoradiography With Insulin Loading in Aged Mice. Frontiers in nutrition\| PubMed ID: 34055854	2021
The deletion of glucagon-like peptide-1 receptors expressing neurons in the dorsomedial hypothalamic nucleus disrupts the diurnal feeding pattern and induces hyperphagia and obesity. Nutrition & metabolism\| PubMed ID: 34098999	2021