Andrean L. Simons

Interdisciplinary Graduate Program in Human Toxicology, University of Iowa

Affiliated withUniversity of Iowa Iowa State University

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2021

Other Publications

Article	Year
Upregulated interleukin-6 expression contributes to erlotinib resistance in head and neck squamous cell carcinoma. Molecular oncology\| PubMed ID: 25888065	2015
2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells. Cancer research\| PubMed ID: 17409446	2007
Enhanced response of human head and neck cancer xenograft tumors to cisplatin combined with 2-deoxy-D-glucose correlates with increased 18F-FDG uptake as determined by PET imaging. International journal of radiation oncology, biology, physics\| PubMed ID: 17967311	2007
2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress. Free radical biology & medicine\| PubMed ID: 18155176	2008
Cisplatin combined with zidovudine enhances cytotoxicity and oxidative stress in human head and neck cancer cells via a thiol-dependent mechanism. Free radical biology & medicine\| PubMed ID: 18983911	2009
Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells. Cancer biology & therapy\| PubMed ID: 19411865	2009
Inhibition of glutathione and thioredoxin metabolism enhances sensitivity to perifosine in head and neck cancer cells. Journal of oncology\| PubMed ID: 19746172	2009
Glucose deprivation-induced metabolic oxidative stress and cancer therapy. Journal of cancer research and therapeutics\| PubMed ID: 20009288	2009
Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4. Cancer research\| PubMed ID: 21482679	2011
Regulation of pancreatic cancer growth by superoxide. Molecular carcinogenesis\| PubMed ID: 22392697	2013
Susceptibility of human head and neck cancer cells to combined inhibition of glutathione and thioredoxin metabolism. PloS one\| PubMed ID: 23118946	2012
The Justy mutant mouse strain produces a spontaneous murine model of salivary gland cancer with myoepithelial and basal cell differentiation. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 23608756	2013
NOX4 mediates cytoprotective autophagy induced by the EGFR inhibitor erlotinib in head and neck cancer cells. Toxicology and applied pharmacology\| PubMed ID: 23917044	2013
EGFR inhibition induces proinflammatory cytokines via NOX4 in HNSCC. Molecular cancer research : MCR\| PubMed ID: 24048704	2013
MyD88-Dependent Signaling Decreases the Antitumor Efficacy of Epidermal Growth Factor Receptor Inhibition in Head and Neck Cancer Cells. Cancer research\| PubMed ID: 25712126	2015
2-Deoxy-d-glucose Suppresses the In Vivo Antitumor Efficacy of Erlotinib in Head and Neck Squamous Cell Carcinoma Cells. Oncology research\| PubMed ID: 27178822	2016
Interleukin-1 blockade overcomes erlotinib resistance in head and neck squamous cell carcinoma. Oncotarget\| PubMed ID: 27738319	2016
Interleukin-1 alpha increases anti-tumor efficacy of cetuximab in head and neck squamous cell carcinoma. Journal for immunotherapy of cancer\| PubMed ID: 30890189	2019
Impact of Nuclear Interleukin-1 Alpha and EGFR Expression on Recurrence and Survival Outcomes in Oral Squamous Cell Carcinomas. Journal of oncology\| PubMed ID: 31320902	2019
A preliminary analysis of interleukin-1 ligands as potential predictive biomarkers of response to cetuximab. Biomarker research\| PubMed ID: 31346466	2019
immunization of a TLR9 agonist virus-like particle enhances anti-PD1 therapy. Journal for immunotherapy of cancer\| PubMed ID: 33060147	2020
The anti-tumor effects of cetuximab in combination with VTX-2337 are T cell dependent. Scientific reports\| PubMed ID: 33452311	2021
Combining Doxorubicin-Loaded PEGylated Poly(Lactide-co-glycolide) Nanoparticles with Checkpoint Inhibition Safely Enhances Therapeutic Efficacy in a Melanoma Model. ACS biomaterials science & engineering\| PubMed ID: 33463284	2020
Ketogenic Diet with Concurrent Chemoradiation in Head and Neck Squamous Cell Carcinoma: Preclinical and Phase 1 Trial Results. Radiation research\| PubMed ID: 34087943	2021