Nikolaus Rajewsky

Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrueck Center for Molecular Medicine (MDC)

Affiliated withMax Delbrueck Center for Molecular Medicine (MDC)Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC)Max Delbrück Center for Molecular Medicine (MDC)

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 9	2021
Publication title Cited by 10	2021
Publication title	2024

Other Publications

Article	Year
Efficient CRISPR/Cas9-Mediated Gene Knockin in Mouse Hematopoietic Stem and Progenitor Cells. Cell reports\| PubMed ID: 31553918	2019
The embryo at single-cell transcriptome resolution. Science (New York, N.Y.)\| PubMed ID: 28860209	2017
Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4 and CD8 T cell responses. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 29311309	2018
Post-transcriptional Regulation by 3' UTRs Can Be Masked by Regulatory Elements in 5' UTRs. Cell reports\| PubMed ID: 29562178	2018
Cell type atlas and lineage tree of a whole complex animal by single-cell transcriptomics. Science (New York, N.Y.)\| PubMed ID: 29674432	2018
Spatiotemporal m(i)RNA Architecture and 3' UTR Regulation in the C. elegans Germline. Developmental cell\| PubMed ID: 30416012	2018
Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis. Cell reports\| PubMed ID: 30485812	2018
BCR-dependent lineage plasticity in mature B cells. Science (New York, N.Y.)\| PubMed ID: 30765568	2019
FLAM-seq: full-length mRNA sequencing reveals principles of poly(A) tail length control. Nature methods\| PubMed ID: 31384046	2019
Identification of proteins and miRNAs that specifically bind an mRNA in vivo. Nature communications\| PubMed ID: 31527589	2019
Gene expression cartography. Nature\| PubMed ID: 31748748	2019
A Highly Conserved Circular RNA Is Required to Keep Neural Cells in a Progenitor State in the Mammalian Brain. Cell reports\| PubMed ID: 32075758	2020
Tracing tumorigenesis in a solid tumor model at single-cell resolution. Nature communications\| PubMed ID: 32080185	2020
Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32522871	2020
CRISPR-Cas9-Mediated ELANE Mutation Correction in Hematopoietic Stem and Progenitor Cells to Treat Severe Congenital Neutropenia. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 32822592	2020
LifeTime and improving European healthcare through cell-based interceptive medicine. Nature\| PubMed ID: 32894860	2020
Kidney Single-cell Transcriptomes Predict Spatial Corticomedullary Gene Expression and Tissue Osmolality Gradients. Journal of the American Society of Nephrology : JASN\| PubMed ID: 33239393	2021
Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine. Nature\| PubMed ID: 33731935	2021
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome. Nature communications\| PubMed ID: 33771987	2021
Parallel genetics of regulatory sequences using scalable genome editing in vivo. Cell reports\| PubMed ID: 33852857	2021
ciRS-7 and miR-7 regulate ischemia-induced neuronal death via glutamatergic signaling. Cell reports\| PubMed ID: 38446664	2024
Widespread changes in protein synthesis induced by microRNAs. Nature\| PubMed ID: 18668040	2008
Mixed messages: Re-initiation factors regulate translation of animal mRNAs. Cell research\| PubMed ID: 25145358	2014
circBase: a database for circular RNAs. RNA (New York, N.Y.)\| PubMed ID: 25234927	2014
circRNA biogenesis competes with pre-mRNA splicing. Molecular cell\| PubMed ID: 25242144	2014
A variety of dicer substrates in human and C. elegans. Cell\| PubMed ID: 25416952	2014
Analysis of intron sequences reveals hallmarks of circular RNA biogenesis in animals. Cell reports\| PubMed ID: 25558066	2015
Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function. The EMBO journal\| PubMed ID: 25828096	2015
Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed. Molecular cell\| PubMed ID: 25921068	2015
Translational regulation shapes the molecular landscape of complex disease phenotypes. Nature communications\| PubMed ID: 26007203	2015
Extensive identification and analysis of conserved small ORFs in animals. Genome biology\| PubMed ID: 26364619	2015
RCAS: an RNA centric annotation system for transcriptome-wide regions of interest. Nucleic acids research\| PubMed ID: 28334930	2017
Cell fixation and preservation for droplet-based single-cell transcriptomics. BMC biology\| PubMed ID: 28526029	2017
Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function. Science (New York, N.Y.)\| PubMed ID: 28798046	2017
A map of human circular RNAs in clinically relevant tissues. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 28842720	2017
RNA localization is a key determinant of neurite-enriched proteome. Nature communications\| PubMed ID: 28928394	2017
Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection. Genome biology\| PubMed ID: 29089033	2017
Single-Molecule Fluorescence In Situ Hybridization (FISH) of Circular RNA CDR1as. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29322442	2018
A Single-Cell Transcriptome Atlas of the Mouse Glomerulus. Journal of the American Society of Nephrology : JASN\| PubMed ID: 29794128	2018
The Translational Landscape of the Human Heart. Cell\| PubMed ID: 31155234	2019
Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program. Nature communications\| PubMed ID: 31653857	2019
NovoSpaRc: flexible spatial reconstruction of single-cell gene expression with optimal transport. Nature protocols\| PubMed ID: 34349282	2021
Spacemake: processing and analysis of large-scale spatial transcriptomics data. GigaScience\| PubMed ID: 35852420	2022
Urinary single-cell sequencing captures kidney injury and repair processes in human acute kidney injury. Kidney international\| PubMed ID: 36049643	2022
SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolution. The Science of the total environment\| PubMed ID: 36228784	2022
Long-term imaging reveals behavioral plasticity during C. elegans dauer exit. BMC biology\| PubMed ID: 36514066	2022
Prox2 and Runx3 vagal sensory neurons regulate esophageal motility. Neuron\| PubMed ID: 37192624	2023
Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche. Nature communications\| PubMed ID: 37230989	2023
Modelling viral encephalitis caused by herpes simplex virus 1 infection in cerebral organoids. Nature microbiology\| PubMed ID: 37349587	2023
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN. Nature communications\| PubMed ID: 37402719	2023
Spatiotemporal, optogenetic control of gene expression in organoids. Nature methods\| PubMed ID: 37735569	2023