Michael F. Olson

The Beatson Institute for Cancer Research

Affiliated withThe Beatson Institute for Cancer Research

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 20	2011

Other Publications

Article	Year
Gem GTPase: between a ROCK and a hard place. Current biology : CB\| PubMed ID: 12176351	2002
Dispatch. GTPase signalling: new functions for Diaphanous-related formins. Current biology : CB\| PubMed ID: 12725753	2003
Ras promotes p21(Waf1/Cip1) protein stability via a cyclin D1-imposed block in proteasome-mediated degradation. The EMBO journal\| PubMed ID: 12727871	2003
Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells. Molecular biology of the cell\| PubMed ID: 12857854	2003
Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathway. Current biology : CB\| PubMed ID: 14680635	2003
Rac transformation: the actin connection. Cancer biology & therapy\| PubMed ID: 14726705	2004
Contraction reaction: mechanical regulation of Rho GTPase. Trends in cell biology\| PubMed ID: 15055199	2004
RAS and RHO GTPases in G1-phase cell-cycle regulation. Nature reviews. Molecular cell biology\| PubMed ID: 15122349	2004
SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant. Cancer research\| PubMed ID: 15313890	2004
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis. Cancer research\| PubMed ID: 15604264	2004
Actin-myosin-based contraction is responsible for apoptotic nuclear disintegration. The Journal of cell biology\| PubMed ID: 15657395	2005
Targeting Ras and Rho GTPases as opportunities for cancer therapeutics. Current opinion in genetics & development\| PubMed ID: 15661535	2005
Modeling human cancer: report on the Eighth Beatson International Cancer Conference. Cancer research\| PubMed ID: 16357126	2005
AP-1 differentially expressed proteins Krp1 and fibronectin cooperatively enhance Rho-ROCK-independent mesenchymal invasion by altering the function, localization, and activity of nondiffere... Molecular and cellular biology\| PubMed ID: 16449658	2006
Purification of TAT-C3 exoenzyme. Methods in enzymology\| PubMed ID: 16472655	2006
Conditional regulation of a ROCK-estrogen receptor fusion protein. Methods in enzymology\| PubMed ID: 16472686	2006
The Rho GTPase effector ROCK regulates cyclin A, cyclin D1, and p27Kip1 levels by distinct mechanisms. Molecular and cellular biology\| PubMed ID: 16738326	2006
LIM kinases: function, regulation and association with human disease. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 17294230	2007
Mechanisms of tumour cell invasion and metastasis. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 17404698	2007
The ras signalling pathway as a target in cancer therapy. Recent results in cancer research. Fortschritte der Krebsforschung. ProgrÃ¨s dans les recherches sur le cancer\| PubMed ID: 17607939	2007
Alpha(E)-Catenin induces SRF-dependent transcriptional activity through its C-terminal region and is partly RhoA/ROCK-dependent. Biochemical and biophysical research communications\| PubMed ID: 18078809	2008
Applications for ROCK kinase inhibition. Current opinion in cell biology\| PubMed ID: 18282695	2008
The actin cytoskeleton in cancer cell motility. Clinical & experimental metastasis\| PubMed ID: 18498004	2009
Regulating the conversion between rounded and elongated modes of cancer cell movement. Cancer cell\| PubMed ID: 18977323	2008
Tissue selective expression of conditionally-regulated ROCK by gene targeting to a defined locus. Genesis (New York, N.Y. : 2000)\| PubMed ID: 19391117	2009
Constitutively active RhoA inhibits proliferation by retarding G(1) to S phase cell cycle progression and impairing cytokinesis. European journal of cell biology\| PubMed ID: 19515453	2009
Sprouty2 association with B-Raf is regulated by phosphorylation and kinase conformation. Cancer research\| PubMed ID: 19690147	2009
MST kinases monitor actin cytoskeletal integrity and signal via c-Jun N-terminal kinase stress-activated kinase to regulate p21Waf1/Cip1 stability. Molecular and cellular biology\| PubMed ID: 19822666	2009
Dying alone: a tale of rho. Cell stem cell\| PubMed ID: 20682437	2010
LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells. The Journal of cell biology\| PubMed ID: 20876278	2010
Differing contributions of LIMK and ROCK to TGFÎ²-induced transcription, motility and invasion. European journal of cell biology\| PubMed ID: 21074289	2011
p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival. Cell research\| PubMed ID: 21079653	2011
Follow the leader: LIM kinases pave the way for collective tumor cell invasion. Cell cycle (Georgetown, Tex.)\| PubMed ID: 21088476	2010
Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53. Cancer research\| PubMed ID: 21266354	2011
K-Ras mediated murine epidermal tumorigenesis is dependent upon and associated with elevated Rac1 activity. PloS one\| PubMed ID: 21358804	2011
Actomyosin-mediated cellular tension drives increased tissue stiffness and Î²-catenin activation to induce epidermal hyperplasia and tumor growth. Cancer cell\| PubMed ID: 21665151	2011
Trailblazing LIM kinases take the lead in collective tumor cell invasion. Bioarchitecture\| PubMed ID: 21866254	2011
Co-crystal structures of inhibitors with MRCKÎ², a key regulator of tumor cell invasion. PloS one\| PubMed ID: 21949762	2011
Actomyosin contractililty: force power drives tumor growth. Cell cycle (Georgetown, Tex.)\| PubMed ID: 22067650	2011
The development of a rat in vitro model of spinal cord injury demonstrating the additive effects of rho and ROCK inhibitors on neurite outgrowth and myelination. Glia\| PubMed ID: 22139636	2012
Development of a High-Throughput Screening Method for LIM Kinase 1 Using a Luciferase-Based Assay of ATP Consumption. Journal of biomolecular screening\| PubMed ID: 22156225	2011
Transcriptional regulation of Rho GTPase signaling. Transcription\| PubMed ID: 22231116	2011
Targeting Rho GTPase signaling for cancer therapy. Future oncology (London, England)\| PubMed ID: 22335581	2012