Helen Reeves

Helen Reeves

Newcastle University Translational and Clinical Research Institute, Newcastle University

Affiliated withNewcastle UniversityNewcastle-upon-Tyne Hospitals NHS Foundation Trust

Research Area

Biography

Helen Reeves graduated from Nottingham Medical school in 1990, moving shortly afterwards to Newcastle-upon-Tyne under the mentorship of Professor Oliver James. She completed a PhD studying cell signaling pathways in liver fibrosis and then worked as a post-doctoral scientist with Professor Scott Friedman at Mount Sinai Medical School in New York, studying aspects of the molecular pathogenesis of cancers. Presently she is Professor of Liver Cancer in the Newcastle University Center for Cancer and is the clinical lead for the care of patients with hepatocellular carcinoma in North East England and Cumbria. She has been a scientific committee member for the British Association for Cancer Research and the European Association for Study of the Liver. She is an active member of the HCC-UK Committee. Her main research focus is on HCC in patients with NAFLD and in the development of clinically relevant biomarkers. She also has a keen interest in the promotion of education and training of young scientific investigators and clinical researchers. She has a program grant from CRUK centred on exploring the roles of neutrophils in liver cancer. She is also the PI for the Liver Cancer focused Accelerator award, jointly funded by CRUK, FC AECC and AIRC entitled ‘HUNTER: Hepatocellular Carcinoma Expediter Network’.

JoVE Journal Publications

ArticleTotal : 1
Year
A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Publication title

Cited by 6

2021

Other Publications

Article
Year
The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease.

Gastroenterology| PubMed ID: 18515091

2008
2008
2009
2011
2012
2013
2014
The rate of production of uric acid by hepatocytes is a sensitive index of compromised cell ATP homeostasis.

American journal of physiology. Endocrinology and metabolism| PubMed ID: 24045866

2013
The detection of hepatocellular carcinoma using a prospectively developed and validated model based on serological biomarkers.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology| PubMed ID: 24220911

2014
2014
2014
DNA-PK-A candidate driver of hepatocarcinogenesis and tissue biomarker that predicts response to treatment and survival.

Clinical cancer research : an official journal of the American Association for Cancer Research| PubMed ID: 25480831

2015
2015
2015
2015
2015
2016
Assessment of the Hong Kong Liver Cancer Staging System in Europe.

Liver international : official journal of the International Association for the Study of the Liver| PubMed ID: 26677809

2016
Hepatocellular Carcinoma in Obesity, Type 2 Diabetes, and NAFLD.

Digestive diseases and sciences| PubMed ID: 26921078

2016
2016
2016
2016
2017
2016
2017
2017
2018
NAFLD-which patients should have hepatocellular carcinoma surveillance?

Hepatobiliary surgery and nutrition| PubMed ID: 29152488

2017
2017
2018
Liquid biopsy for liver diseases.

Gut| PubMed ID: 30177542

2018
2018
Fatty Liver Disease and Hepatocellular Carcinoma: The Pathologist's View.

Advances in experimental medicine and biology| PubMed ID: 30362090

2018
2019
The CCR2 Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers.

Cellular and molecular gastroenterology and hepatology| PubMed ID: 30704985

2019
2019
From NASH to HCC: current concepts and future challenges.

Nature reviews. Gastroenterology & hepatology| PubMed ID: 31028350

2019
2020
2020
2021
High subcutaneous adipose tissue density correlates negatively with survival in patients with hepatocellular carcinoma.

Liver international : official journal of the International Association for the Study of the Liver| PubMed ID: 33280219

2021
Treatment strategies for early stage hepatocellular carcinoma: a systematic review and network meta-analysis of randomised clinical trials.

HPB : the official journal of the International Hepato Pancreato Biliary Association| PubMed ID: 33309569

2021
2021
2021
2021
NAFLD-Associated HCC: Progress and Opportunities.

Journal of hepatocellular carcinoma| PubMed ID: 33854987

2021
2021
Combined hepatocellular-cholangiocarcinoma - More questions than answers.

Liver international : official journal of the International Association for the Study of the Liver| PubMed ID: 34002474

2021
2021
2021
2021