Stuart G. Campbell

Department of Biomedical Engineering, Yale University

Affiliated withYale University Yale School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 7	2022

Other Publications

Article	Year
Timing and magnitude of systolic stretch affect myofilament activation and mechanical work. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 24878774	2014
Decreased polycystin 2 expression alters calcium-contraction coupling and changes β-adrenergic signaling pathways. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25368166	2014
Mathematical modeling of aortic valve dynamics during systole. Journal of theoretical biology\| PubMed ID: 25451522	2015
Prospects for In Vitro Myofilament Maturation in Stem Cell-Derived Cardiac Myocytes. Biomarker insights\| PubMed ID: 26085788	2015
Slowing of contractile kinetics by myosin-binding protein C can be explained by its cooperative binding to the thin filament. Journal of molecular and cellular cardiology\| PubMed ID: 26454159	2016
Modeling predicts a connection between sinus vortex effects and aortic compliance. Journal of theoretical biology\| PubMed ID: 26585547	2016
Contributions of Ca2+-Independent Thin Filament Activation to Cardiac Muscle Function. Biophysical journal\| PubMed ID: 26588569	2015
Structural determinants of muscle thin filament cooperativity. Archives of biochemistry and biophysics\| PubMed ID: 26891592	2016
Anisotropic engineered heart tissue made from laser-cut decellularized myocardium. Scientific reports\| PubMed ID: 27572147	2016
Acute Optogenetic Modulation of Cardiac Twitch Dynamics Explored Through Modeling. Journal of biomechanical engineering\| PubMed ID: 27618140	2016
Low-dose dasatinib rescues cardiac function in Noonan syndrome. JCI insight\| PubMed ID: 27942593	2016
A Protocol for Collecting Human Cardiac Tissue for Research. The VAD journal : the journal of mechanical assisted circulation and heart failure\| PubMed ID: 28042604	2016
Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca-dependent manner. Scientific reports\| PubMed ID: 29422607	2018
Force-Dependent Recruitment from the Myosin Off State Contributes to Length-Dependent Activation. Biophysical journal\| PubMed ID: 30054031	2018
Precise Binding of Tropomyosin on Actin Involves Sequence-Dependent Variance in Coiled-Coil Twisting. Biophysical journal\| PubMed ID: 30195938	2018
Diverse relaxation rates exist among rat cardiomyocytes isolated from a single myocardial region. The Journal of physiology\| PubMed ID: 30315728	2019
A short history of the development of mathematical models of cardiac mechanics. Journal of molecular and cellular cardiology\| PubMed ID: 30503754	2019
Modelling sarcomeric cardiomyopathies with human cardiomyocytes derived from induced pluripotent stem cells. The Journal of physiology\| PubMed ID: 30624779	2020
Sarcomere-Directed Calcium Reporters in Cardiomyocytes. Circulation research\| PubMed ID: 30973804	2019
The Effect of Tropomyosin Mutations on Actin-Tropomyosin Binding: In Search of Lost Time. Biophysical journal\| PubMed ID: 31130236	2019
Patient mutations linked to arrhythmogenic cardiomyopathy enhance calpain-mediated desmoplakin degradation. JCI insight\| PubMed ID: 31194698	2019
Extracellular Matrix From Hypertrophic Myocardium Provokes Impaired Twitch Dynamics in Healthy Cardiomyocytes. JACC. Basic to translational science\| PubMed ID: 31468004	2019
Cardiomyocyte d-dopachrome tautomerase protects against heart failure. JCI insight\| PubMed ID: 31484822	2019
A Microwell Cell Capture Device Reveals Variable Response to Dobutamine in Isolated Cardiomyocytes. Biophysical journal\| PubMed ID: 31537313	2019
Modular design of a tissue engineered pulsatile conduit using human induced pluripotent stem cell-derived cardiomyocytes. Acta biomaterialia\| PubMed ID: 31634626	2020
KBTBD13 and the ever-expanding sarcomeric universe. The Journal of clinical investigation\| PubMed ID: 31904591	2020
Polycystin 2 is increased in disease to protect against stress-induced cell death. Scientific reports\| PubMed ID: 31941974	2020
Contractile work directly modulates mitochondrial protein levels in human engineered heart tissues. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 32383992	2020
Multiscale Modeling of Cardiovascular Function Predicts That the End-Systolic Pressure Volume Relationship Can Be Targeted via Multiple Therapeutic Strategies. Frontiers in physiology\| PubMed ID: 32973561	2020
Fast-relaxing cardiomyocytes exert a dominant role in the relaxation behavior of heterogeneous myocardium. Archives of biochemistry and biophysics\| PubMed ID: 33271148	2021
Mavacamten preserves length-dependent contractility and improves diastolic function in human engineered heart tissue. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 33449850	2021
Potential impacts of the cardiac troponin I mobile domain on myofilament activation and relaxation. Journal of molecular and cellular cardiology\| PubMed ID: 33647310	2021
Evidence for synergy between sarcomeres and fibroblasts in an in vitro model of myocardial reverse remodeling. Journal of molecular and cellular cardiology\| PubMed ID: 33992697	2021
Danicamtiv Enhances Systolic Function and Frank-Starling Behavior at Minimal Diastolic Cost in Engineered Human Myocardium. Journal of the American Heart Association\| PubMed ID: 34096321	2021
Loss of crossbridge inhibition drives pathological cardiac hypertrophy in patients harboring the TPM1 E192K mutation. The Journal of general physiology\| PubMed ID: 34319370	2021
Myofilament glycation in diabetes reduces contractility by inhibiting tropomyosin movement, is rescued by cMyBPC domains. Journal of molecular and cellular cardiology\| PubMed ID: 34487755	2022
MicroRNA function can be reversed by altering target gene expression levels. iScience\| PubMed ID: 34755085	2021
Functional and structural differences between skinned and intact muscle preparations. The Journal of general physiology\| PubMed ID: 35045156	2022