Galit Alter

Massachusetts General Hospital, Ragon Institute of MGH, MIT, and Harvard

Affiliated withRagon Institute of MGH, MIT, and Harvard

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 33	2011

Other Publications

Article	Year
Human immunodeficiency virus (HIV)-specific effector CD8 T cell activity in patients with primary HIV infection. The Journal of infectious diseases\| PubMed ID: 11920293	2002
HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8(+) T cells producing both interferon-gamma and tumor necrosis factor-alpha. Blood\| PubMed ID: 15059848	2004
Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells. The Journal of experimental medicine\| PubMed ID: 15381726	2004
Increased natural killer cell activity in viremic HIV-1 infection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15470077	2004
Assessment of longitudinal changes in HIV-specific effector activity in subjects undergoing untreated primary HIV infection. AIDS (London, England)\| PubMed ID: 15577619	2004
CD107a as a functional marker for the identification of natural killer cell activity. Journal of immunological methods\| PubMed ID: 15604012	2004
Human immunodeficiency virus (HIV)-specific gamma interferon secretion directed against all expressed HIV genes: relationship to rate of CD4 decline. Journal of virology\| PubMed ID: 15795276	2005
The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted... Journal of virology\| PubMed ID: 15795285	2005
Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection. Blood\| PubMed ID: 16002429	2005
High degree of inter-clade cross-reactivity of HIV-1-specific T cell responses at the single peptide level. AIDS (London, England)\| PubMed ID: 16135897	2005
De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection. Journal of virology\| PubMed ID: 16188997	2005
Consistent effects of TSG101 genetic variability on multiple outcomes of exposure to human immunodeficiency virus type 1. Journal of virology\| PubMed ID: 16809281	2006
Low perforin and elevated SHIP-1 expression is associated with functional anergy of natural killer cells in chronic HIV-1 infection. AIDS (London, England)\| PubMed ID: 16847410	2006
Immunological and virological impact of highly active antiretroviral therapy initiated during acute HIV-1 infection. The Journal of infectious diseases\| PubMed ID: 16941338	2006
NK cell function in HIV-1 infection. Current molecular medicine\| PubMed ID: 17022732	2006
HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1. PLoS medicine\| PubMed ID: 17076553	2006
Evolution of innate and adaptive effector cell functions during acute HIV-1 infection. The Journal of infectious diseases\| PubMed ID: 17436225	2007
Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles. Journal of virology\| PubMed ID: 17494064	2007
MyD88-dependent immune activation mediated by human immunodeficiency virus type 1-encoded Toll-like receptor ligands. Journal of virology\| PubMed ID: 17507480	2007
Single-stranded RNA derived from HIV-1 serves as a potent activator of NK cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17548602	2007
Detection of KIR3DS1 on the cell surface of peripheral blood NK cells facilitates identification of a novel null allele and assessment of KIR3DS1 expression during HIV-1 infection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17641029	2007
Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes. The Journal of experimental medicine\| PubMed ID: 18025129	2007
Rapid ex vivo isolation and long-term culture of human Th17 cells. Journal of immunological methods\| PubMed ID: 18314131	2008
Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands. AIDS (London, England)\| PubMed ID: 18317010	2008
Novel KIR3DL1 alleles and their expression levels on NK cells: convergent evolution of KIR3DL1 phenotype variation? Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18453594	2008
Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells. PLoS medicine\| PubMed ID: 18462013	2008
Ligand-independent exhaustion of killer immunoglobulin-like receptor-positive CD8+ T cells in human immunodeficiency virus type 1 infection. Journal of virology\| PubMed ID: 18579582	2008
Rapid loss of dendritic cell and monocyte responses to TLR ligands following venipuncture. Journal of immunological methods\| PubMed ID: 18848564	2008
Type 2 Bias of T cells expanded from the blood of melanoma patients switched to type 1 by IL-12p70 mRNA-transfected dendritic cells. Cancer research\| PubMed ID: 19010919	2008
Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus ... Journal of virology\| PubMed ID: 19036810	2009
Report on the AIDS Vaccine 2008 Conference. Human vaccines\| PubMed ID: 19202348	2009
Biology of plasmacytoid dendritic cells and natural killer cells in HIV-1 infection. Current opinion in HIV and AIDS\| PubMed ID: 19372886	2007
HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection. Journal of virology\| PubMed ID: 19386717	2009
Matrix metalloprotease inhibitors restore impaired NK cell-mediated antibody-dependent cellular cytotoxicity in human immunodeficiency virus type 1 infection. Journal of virology\| PubMed ID: 19553339	2009
Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1. Nature medicine\| PubMed ID: 19597505	2009
Challenges facing young investigators. IAVI report : newsletter on international AIDS vaccine research\| PubMed ID: 20214278	2009
Perspective natural killer cells: bridging innate and adaptive immunity? IAVI report : newsletter on international AIDS vaccine research\| PubMed ID: 20217934	2006
Alterations in natural killer cell receptor profiles during HIV type 1 disease progression among chronically infected South African adults. AIDS research and human retroviruses\| PubMed ID: 20380481	2010
IL-10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infection. The Journal of clinical investigation\| PubMed ID: 20440075	2010
MHC class I chain-related protein A shedding in chronic HIV-1 infection is associated with profound NK cell dysfunction. Virology\| PubMed ID: 20667578	2010
The humoral response to HIV-1: new insights, renewed focus. The Journal of infectious diseases\| PubMed ID: 20846039	2010
Determinants of protection among HIVâ€exposed seronegative persons: an overview. The Journal of infectious diseases\| PubMed ID: 20887220	2010
Comprehensive analysis of virus-specific T-cells provides clues for the failure of therapeutic immunization with ALVAC-HIV vaccine. AIDS (London, England)\| PubMed ID: 21076273	2011
Reduced frequencies of NKp30+NKp46+, CD161+, and NKG2D+ NK cells in acute HCV infection may predict viral clearance. Journal of hepatology\| PubMed ID: 21168454	2011
A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples. Journal of immunological methods\| PubMed ID: 21192942	2011
Expansion of 2B4+ natural killer (NK) cells and decrease in NKp46+ NK cells in response to influenza. Immunology\| PubMed ID: 21214542	2011
Characteristics of the earliest cross-neutralizing antibody response to HIV-1. PLoS pathogens\| PubMed ID: 21249232	2011
Natural killer cells in spontaneous control of HIV infection. Current opinion in HIV and AIDS\| PubMed ID: 21399495	2011
Mutiny or scrutiny: NK cell modulation of DC function in HIV-1 infection. Trends in immunology\| PubMed ID: 21411368	2011
KIR polymorphisms modulate peptide-dependent binding to an MHC class I ligand with a Bw6 motif. PLoS pathogens\| PubMed ID: 21423672	2011
Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals. Virology\| PubMed ID: 21565376	2011
Early viral replication in lymph nodes provides HIV with a means by which to escape NK-cell-mediated control. European journal of immunology\| PubMed ID: 21630248	2011
HIV-1 adaptation to NK-cell-mediated immune pressure. Nature\| PubMed ID: 21814282	2011
KIR/HLA: genetic clues for a role of NK cells in the control of HIV. Advances in experimental medicine and biology\| PubMed ID: 21842362	2011
Emerging Concepts on the Role of Innate Immunity in the Prevention and Control of HIV Infection. Annual review of medicine\| PubMed ID: 22077718	2012
Copy number variation of KIR genes influences HIV-1 control. PLoS biology\| PubMed ID: 22140359	2011