Alexander Quaas

Institute of Pathology, University Hospital Cologne

Affiliated withUniversity Hospital Cologne

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2022

Other Publications

Article	Year
Oncogene and therapeutic target analyses in atypical fibroxanthomas and pleomorphic dermal sarcomas. Oncotarget\| PubMed ID: 26943575	2016
MDM2 and CDK4 amplifications are rare events in salivary duct carcinomas. Oncotarget\| PubMed ID: 27662657	2016
New concepts of personalized therapy in salivary gland carcinomas. Oral oncology\| PubMed ID: 28325631	2017
Copy number variations in atypical fibroxanthomas and pleomorphic dermal sarcomas. Oncotarget\| PubMed ID: 29312620	2017
Low SOX2 expression marks a distinct subset of adenoid cystic carcinoma of the head and neck and is associated with an advanced tumor stage. PloS one\| PubMed ID: 29596469	2018
gene amplification is a rare event in atypical fibroxanthoma and pleomorphic dermal sarcoma. Oncotarget\| PubMed ID: 29765529	2018
Therapy susceptible germline-related BRCA 1-mutation in a case of metastasized mixed adeno-neuroendocrine carcinoma (MANEC) of the small bowel. BMC gastroenterology\| PubMed ID: 29855275	2018
Immunohistochemical expression of melanocytic and myofibroblastic markers and their molecular correlation in atypical fibroxanthomas and pleomorphic dermal sarcomas. Journal of cutaneous pathology\| PubMed ID: 30155964	2018
Somatic alterations in circulating cell-free DNA of oesophageal carcinoma patients during primary staging are indicative for post-surgical tumour recurrence. Scientific reports\| PubMed ID: 30297788	2018
Genomic Characterization of TP53-Wild-Type Esophageal Carcinoma. Translational oncology\| PubMed ID: 30317074	2019
HER2/neu (ERBB2) expression and gene amplification correlates with better survival in esophageal adenocarcinoma. BMC cancer\| PubMed ID: 30621632	2019
Alterations in ERBB2 and BRCA and microsatellite instability as new personalized treatment options in small bowel carcinoma. BMC gastroenterology\| PubMed ID: 30717682	2019
Tumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma. Oncoimmunology\| PubMed ID: 30723574	2019
p53 overexpression is a prognosticator of poor outcome in esophageal cancer. Oncology letters\| PubMed ID: 30881503	2019
Successful use of TNFα blockade in a severe case of idiopathic non-granulomatous ulcerative jejunoileitis associated with thrombotic thrombocytopenic purpura. BMJ open gastroenterology\| PubMed ID: 30899536	2019
Immune-phenotyping of pleomorphic dermal sarcomas suggests this entity as a potential candidate for immunotherapy. Cancer immunology, immunotherapy : CII\| PubMed ID: 30963193	2019
Upregulation of miR-17-92 cluster is associated with progression and lymph node metastasis in oesophageal adenocarcinoma. Scientific reports\| PubMed ID: 31431687	2019
First report on two cases of pleomorphic dermal sarcoma successfully treated with immune checkpoint inhibitors. Oncoimmunology\| PubMed ID: 31741767	2019
PIK3CA and KRAS Amplification in Esophageal Adenocarcinoma and their Impact on the Inflammatory Tumor Microenvironment and Prognosis. Translational oncology\| PubMed ID: 31865178	2020
Diagnostic Challenges and Treatment Options for Cutaneous T Cell Pseudolymphoma: A Case Study with Rituximab Treatment. The American journal of case reports\| PubMed ID: 31919337	2020
Immune profile and immunosurveillance in treatment-naive and neoadjuvantly treated esophageal adenocarcinoma. Cancer immunology, immunotherapy : CII\| PubMed ID: 31960110	2020
Cell type-specific transcriptomics of esophageal adenocarcinoma as a scalable alternative for single cell transcriptomics. Molecular oncology\| PubMed ID: 32255255	2020
Amplification of KRAS and its heterogeneity in non-Asian gastric adenocarcinomas. BMC cancer\| PubMed ID: 32571252	2020
Y Chromosome Loss is a Frequent Event in Barrett's Adenocarcinoma and Associated with Poor Outcome. Cancers\| PubMed ID: 32629877	2020
PD-L1 Expression and a High Tumor Infiltrate of CD8+ Lymphocytes Predict Outcome in Patients with Oropharyngeal Squamous Cells Carcinoma. International journal of molecular sciences\| PubMed ID: 32718057	2020
Tumor budding assessed according to the criteria of the International Tumor Budding Consensus Conference determines prognosis in resected esophageal adenocarcinoma. Virchows Archiv : an international journal of pathology\| PubMed ID: 32761393	2021
Integrative Analysis of Pleomorphic Dermal Sarcomas Reveals Fibroblastic Differentiation and Susceptibility to Immunotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 32817080	2020
Maternal exercise conveys protection against NAFLD in the offspring via hepatic metabolic programming. Scientific reports\| PubMed ID: 32963289	2020
Microwave ablation enhances tumor-specific immune response in patients with hepatocellular carcinoma. Cancer immunology, immunotherapy : CII\| PubMed ID: 33006650	2021
Indoleamine 2,3-Dioxygenase (IDO) Expression Is an Independent Prognostic Marker in Esophageal Adenocarcinoma. Journal of immunology research\| PubMed ID: 33029538	2020
ATP synthase modulation leads to an increase of spare respiratory capacity in HPV associated cancers. Scientific reports\| PubMed ID: 33060693	2020
Interferon-Induced Protein With Multiple Tetratricopeptide Repeats 3 Is Associated With Response to Chemotherapy and Recurrence but Not With Survival. Pancreas\| PubMed ID: 33122518	2020
Regorafenib combined with PD1 blockade increases CD8 T-cell infiltration by inducing CXCL10 expression in hepatocellular carcinoma. Journal for immunotherapy of cancer\| PubMed ID: 33234602	2020
Deep Learning Predicts HPV Association in Oropharyngeal Squamous Cell Carcinomas and Identifies Patients with a Favorable Prognosis Using Regular H&E Stains. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 33262137	2021
GATA binding protein 6 (GATA6) is co-amplified with PIK3CA in patients with esophageal adenocarcinoma and is linked to neoadjuvant therapy. Journal of cancer research and clinical oncology\| PubMed ID: 33300112	2020
Deep learning for sensitive detection of Helicobacter Pylori in gastric biopsies. BMC gastroenterology\| PubMed ID: 33308189	2020
LAG-3, TIM-3 and VISTA Expression on Tumor-Infiltrating Lymphocytes in Oropharyngeal Squamous Cell Carcinoma-Potential Biomarkers for Targeted Therapy Concepts. International journal of molecular sciences\| PubMed ID: 33396515	2020
Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma. Gut\| PubMed ID: 33431577	2022
Tumor infiltrating lymphocyte clusters are associated with response to immune checkpoint inhibition in BRAF V600 mutated malignant melanomas. Scientific reports\| PubMed ID: 33469107	2021
Protein-loss of SWI/SNF-complex core subunits influences prognosis dependent on histological subtypes of intra- and extrahepatic cholangiocarcinoma. Oncology letters\| PubMed ID: 33747206	2021
Trophoblast Cell Surface Antigen 2 (Trop-2) Protein is Highly Expressed in Salivary Gland Carcinomas and Represents a Potential Therapeutic Target. Head and neck pathology\| PubMed ID: 33886073	2021
Optimized PD-L1 scoring of gastric cancer. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association\| PubMed ID: 33954872	2021
Sex-specific prognostic effect of CD66b-positive tumor-infiltrating neutrophils (TANs) in gastric and esophageal adenocarcinoma. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association\| PubMed ID: 34009535	2021
Maternal Exercise Mediates Hepatic Metabolic Programming via Activation of AMPK-PGC1α Axis in the Offspring of Obese Mothers. Cells\| PubMed ID: 34069390	2021
Cancer-specific immune evasion and substantial heterogeneity within cancer types provide evidence for personalized immunotherapy. NPJ precision oncology\| PubMed ID: 34135436	2021
CD86 Antigen-Presenting B Cells Are Increased in Cancer, Localize in Tertiary Lymphoid Structures, and Induce Specific T-cell Responses. Cancer immunology research\| PubMed ID: 34155067	2021
First description of hematogenously metastasized sclerosing epithelioid fibrosarcoma arising in the uterine cervix. Gynecologic oncology reports\| PubMed ID: 34159243	2021
Quality control stress test for deep learning-based diagnostic model in digital pathology. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 34168282	2021
Occurrence of High Microsatellite-Instability/Mismatch Repair Deficiency in Nearly 2,000 Human Adenocarcinomas of the Gastrointestinal Tract, Pancreas, and Bile Ducts: A Study From a Large G... Frontiers in oncology\| PubMed ID: 34367937	2021
Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective multicentre cohort study. The Lancet. Digital health\| PubMed ID: 34417147	2021
Genomic and Transcriptomic Characteristics of Esophageal Adenocarcinoma. Cancers\| PubMed ID: 34503107	2021
MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I. Nature communications\| PubMed ID: 34535668	2021
A Novel Hybrid Stent with Endoscopic Vacuum Therapy for Treating Leaks of the Upper Gastrointestinal Tract. Visceral medicine\| PubMed ID: 34722723	2021
IL-17B/RB Activation in Pancreatic Stellate Cells Promotes Pancreatic Cancer Metabolism and Growth. Cancers\| PubMed ID: 34771503	2021
Genotype Distribution and Prevalence of Human Papillomavirus in Head and Neck Cancer Samples from Istanbul, Turkey. Pathogens (Basel, Switzerland)\| PubMed ID: 34959488	2021
Deep learning based on hematoxylin-eosin staining outperforms immunohistochemistry in predicting molecular subtypes of gastric adenocarcinoma. The Journal of pathology\| PubMed ID: 35119111	2022
Post-transplant Malignancies Show Reduced T-cell Abundance and Tertiary Lymphoid Structures as Correlates of Impaired Cancer Immunosurveillance. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 35191474	2022
Expression of Neighbor of Punc E11 (NOPE) in early stage esophageal adenocarcinoma is associated with reduced survival. Scientific reports\| PubMed ID: 35246597	2022
International Tumor Budding Consensus Conference criteria determine the prognosis of oesophageal adenocarcinoma with poor response to neoadjuvant treatment. Pathology, research and practice\| PubMed ID: 35316631	2022
Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies? Virchows Archiv : an international journal of pathology\| PubMed ID: 35364700	2022
Long-Term Outcome After Histopathological Complete Response with and Without Nodal Metastases Following Multimodal Treatment of Esophageal Cancer. Annals of surgical oncology\| PubMed ID: 35403919	2022
COVID-19 Infection Induce miR-371a-3p Upregulation Resulting in Influence on Male Fertility. Biomedicines\| PubMed ID: 35453608	2022
Fructose-1,6-bisphosphatase 1 (FBP1) is an independent biomarker associated with a favorable prognosis in esophageal adenocarcinoma. Journal of cancer research and clinical oncology\| PubMed ID: 35477823	2022
Influence of patient sex on outcomes after pancreatic surgery: multicentre study. The British journal of surgery\| PubMed ID: 35574811	2022
Perinatal Obesity Induces Hepatic Growth Restriction with Increased DNA Damage Response, Senescence, and Dysregulated Igf-1-Akt-Foxo1 Signaling in Male Offspring of Obese Mice. International journal of molecular sciences\| PubMed ID: 35628414	2022
Hemangiosis carcinomatosa as an independent risk factor for long-term survival in Non-Small Cell Lung Cancer patients. Surgical oncology\| PubMed ID: 35738083	2022