Huijun Sun

College of Pharmacy, Dalian Medical University

Affiliated withDalian Medical University

Research Area

Biography

Professor of Pharmacology, majoring in the research of metabolic disease pharmacology.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2022

Other Publications

Article	Year
Overexpression of human matrix metalloproteinase-12 enhances the development of inflammatory arthritis in transgenic rabbits. The American journal of pathology\| PubMed ID: 15466401	2004
Dioscin strengthens the efficiency of adriamycin in MCF-7 and MCF-7/ADR cells through autophagy induction: More than just down-regulation of MDR1. Scientific reports\| PubMed ID: 27329817	2016
Association of increased expression of macrophage elastase (matrix metalloproteinase 12) with rheumatoid arthritis. Arthritis and rheumatism\| PubMed ID: 15476203	2004
C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance. The American journal of pathology\| PubMed ID: 16192648	2005
Increased expression of human macrophage metalloelastase (MMP-12) is associated with the invasion of endometrial adenocarcinoma. Pathology, research and practice\| PubMed ID: 17574772	2007
Protective effect of JBP485 on concanavalin A-induced hepatocyte toxicity in primary cultured rat hepatocytes. European journal of pharmacology\| PubMed ID: 18571156	2008
Laennec protects murine from concanavalin A-induced liver injury through inhibition of inflammatory reactions and hepatocyte apoptosis. Biological & pharmaceutical bulletin\| PubMed ID: 18981570	2008
Pharmacokinetic interaction between JBP485 and cephalexin in rats. Drug metabolism and disposition: the biological fate of chemicals\| PubMed ID: 20219852	2010
Molecular mechanisms of biliary excretion of cefditoren and the effects of cefditoren on the expression levels of hepatic transporters. Drug metabolism and pharmacokinetics\| PubMed ID: 20814152	2010
Peptide cotransporter 1 in intestine and organic anion transporters in kidney are targets of interaction between JBP485 and lisinopril in rats. Drug metabolism and pharmacokinetics\| PubMed ID: 22123131	2012
Subchronic toxicity study of the total flavonoids from Rosa laevigata Michx fruit in rats. Regulatory toxicology and pharmacology : RTP\| PubMed ID: 22226919	2012
Organic anion transporters involved in the excretion of bestatin in the kidney. Peptides\| PubMed ID: 22273603	2012
Construction, identification and application of HeLa cells stably transfected with human PEPT1 and PEPT2. Peptides\| PubMed ID: 22369721	2012
Effect of JBP485 on obstructive jaundice is related to regulation of renal Oat1, Oat3 and Mrp2 expression in ANIT-treated rats. Peptides\| PubMed ID: 22521734	2012
Inhibitory effect of JBP485 on renal excretion of acyclovir by the inhibition of OAT1 and OAT3. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 22728397	2012
Changes in expression of renal Oat1, Oat3 and Mrp2 in cisplatin-induced acute renal failure after treatment of JBP485 in rats. Toxicology and applied pharmacology\| PubMed ID: 22992436	2012
Inhibitory effect of 1Î±,25-dihydroxyvitamin Dâ‚ƒ on excretion of JBP485 via organic anion transporters in rats. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 23201003	2013
OAT1 and OAT3: targets of drug-drug interaction between entecavir and JBP485. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 23313623	2013
Involvement of organic anion-transporting polypeptides in the hepatic uptake of dioscin in rats and humans. Drug metabolism and disposition: the biological fate of chemicals\| PubMed ID: 23396419	2013
Dioscin Restores the Activity of the Anticancer Agent Adriamycin in Multidrug-Resistant Human Leukemia K562/Adriamycin Cells by Down-Regulating MDR1 via a Mechanism Involving NF-ÎºB Signalin... Journal of natural products\| PubMed ID: 23621869	2013
JBP485 improves gentamicin-induced acute renal failure by regulating the expression and function of Oat1 and Oat3 in rats. Toxicology and applied pharmacology\| PubMed ID: 23707770	2013
Benzylpenicillin inhibits the renal excretion of acyclovir by OAT1 and OAT3. Pharmacological reports : PR\| PubMed ID: 23744435	2013
Anti-cancer effects of dioscin on three kinds of human lung cancer cell lines through inducing DNA damage and activating mitochondrial signal pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association\| PubMed ID: 23764357	2013
Enhancement effect of P-gp inhibitors on the intestinal absorption and antiproliferative activity of bestatin. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 23981338	2013
The oligopeptide transporter 2-mediated reabsorption of entecavir in rat kidney. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 24184752	2014
MDR1 and OAT1/OAT3 mediate the drug-drug interaction between puerarin and methotrexate. Pharmaceutical research\| PubMed ID: 24242937	2014
Inhibitory effect of valsartan on the intestinal absorption and renal excretion of bestatin in rats. Journal of pharmaceutical sciences\| PubMed ID: 24338900	2014
Methotrexate-bestatin interaction: involvement of P-glycoprotein and organic anion transporters in rats. International journal of pharmaceutics\| PubMed ID: 24530518	2014
Luteolin protects HUVECs from TNF-α-induced oxidative stress and inflammation via its effects on the Nox4/ROS-NF-κB and MAPK pathways. Journal of atherosclerosis and thrombosis\| PubMed ID: 24621786	2014
Dioscin enhances methotrexate absorption by down-regulating MDR1 in vitro and in vivo. Toxicology and applied pharmacology\| PubMed ID: 24680847	2014
Aspirin and probenecid inhibit organic anion transporter 3-mediated renal uptake of cilostazol and probenecid induces metabolism of cilostazol in the rat. Drug metabolism and disposition: the biological fate of chemicals\| PubMed ID: 24692216	2014
Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines. Journal of biomedical science\| PubMed ID: 24742230	2014
OATP and MRP2-mediated hepatic uptake and biliary excretion of eprosartan in rat and human. Pharmacological reports : PR\| PubMed ID: 24911086	2014
PEPT1- and OAT1/3-mediated drug-drug interactions between bestatin and cefixime in vivo and in vitro in rats, and in vitro in human. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 25016073	2014
Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice. Pharmaceutical research\| PubMed ID: 25143196	2015
Alisol B 23-acetate promotes liver regeneration in mice after partial hepatectomy via activating farnesoid X receptor. Biochemical pharmacology\| PubMed ID: 25278094	2014
Rhizoma Dioscoreae Nipponicae polysaccharides protect HUVECs from H2O2-induced injury by regulating PPARγ factor and the NADPH oxidase/ROS-NF-κB signal pathway. Toxicology letters\| PubMed ID: 25305479	2015
Naringin inhibits TNF-α induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-κ B and PI3K/Akt pathways. Current pharmaceutical biotechnology\| PubMed ID: 25391245	2014
Dasatinib reverses the multidrug resistance of breast cancer MCF-7 cells to doxorubicin by downregulating P-gp expression via inhibiting the activation of ERK signaling pathway. Cancer biology & therapy\| PubMed ID: 25482933	2015
Potent anti-inflammatory effect of dioscin mediated by suppression of TNF-α-induced VCAM-1, ICAM-1and EL expression via the NF-κB pathway. Biochimie\| PubMed ID: 25577996	2015
Potent effects of dioscin against obesity in mice. Scientific reports\| PubMed ID: 25609476	2015
Decreased liver distribution of entecavir is related to down-regulation of Oat2/Oct1 and up-regulation of Mrp1/2/3/5 in rat liver fibrosis. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 25712368	2015
Protective effects of alisol B 23-acetate from edible botanical Rhizoma alismatis against carbon tetrachloride-induced hepatotoxicity in mice. Food & function\| PubMed ID: 25747392	2015
Potent effects of dioscin against liver fibrosis. Scientific reports\| PubMed ID: 25853178	2015
Protective Effects of Alisol B 23-Acetate Via Farnesoid X Receptor-Mediated Regulation of Transporters and Enzymes in Estrogen-Induced Cholestatic Liver Injury in Mice. Pharmaceutical research\| PubMed ID: 26040663	2015
Dioscin attenuates renal ischemia/reperfusion injury by inhibiting the TLR4/MyD88 signaling pathway via up-regulation of HSP70. Pharmacological research\| PubMed ID: 26348276	2015
Enhancement effect of resveratrol on the intestinal absorption of bestatin by regulating PEPT1, MDR1 and MRP2 in vivo and in vitro. International journal of pharmaceutics\| PubMed ID: 26394120	2015
Bezafibrate-mizoribine interaction: Involvement of organic anion transporters OAT1 and OAT3 in rats. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 26474691	2016
Targeting P-glycoprotein expression and cancer cell energy metabolism: combination of metformin and 2-deoxyglucose reverses the multidrug resistance of K562/Dox cells to doxorubicin. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine\| PubMed ID: 26733176	2016
Chondroprotective effects of alpha-lipoic acid in a rat model of osteoarthritis. Free radical research\| PubMed ID: 27055478	2016
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 27133040	2016
Dioscin reduces ovariectomy-induced bone loss by enhancing osteoblastogenesis and inhibiting osteoclastogenesis. Pharmacological research\| PubMed ID: 27155058	2016
Dioscin protects against ANIT-induced cholestasis via regulating Oatps, Mrp2 and Bsep expression in rats. Toxicology and applied pharmacology\| PubMed ID: 27317372	2016
P-gp, MRP2 and OAT1/OAT3 mediate the drug-drug interaction between resveratrol and methotrexate. Toxicology and applied pharmacology\| PubMed ID: 27377006	2016
Dioscin alleviates lipopolysaccharide-induced inflammatory kidney injury via the microRNA let-7i/TLR4/MyD88 signaling pathway. Pharmacological research\| PubMed ID: 27431331	2016
Protective effects of glycyrrhizic acid from edible botanical glycyrrhiza glabra against non-alcoholic steatohepatitis in mice. Food & function\| PubMed ID: 27487733	2016
Design and synthesis of phosphoryl-substituted diphenylpyrimidines (Pho-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors: Targeted treatment of B lymphoblastic leukemia cell lines. Bioorganic & medicinal chemistry\| PubMed ID: 27956037	2017
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin. Oncotarget\| PubMed ID: 28052008	2017
Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 28190475	2017
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation. Frontiers in pharmacology\| PubMed ID: 28377715	2017
Targeting Oct2 and P53: Formononetin prevents cisplatin-induced acute kidney injury. Toxicology and applied pharmacology\| PubMed ID: 28414026	2017
Protective effects of glycyrrhizic acid against non-alcoholic fatty liver disease in mice. European journal of pharmacology\| PubMed ID: 28414056	2017
Organic Anion-Transporting Polypeptide and Efflux Transporter-Mediated Hepatic Uptake and Biliary Excretion of Cilostazol and Its Metabolites in Rats and Humans. Journal of pharmaceutical sciences\| PubMed ID: 28535976	2017
Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca -mediated apoptosis pathways in MCF-7/ADR and K562/ADR. Journal of cellular physiology\| PubMed ID: 28681913	2018
Effects of calycosin against high-fat diet-induced nonalcoholic fatty liver disease in mice. Journal of gastroenterology and hepatology\| PubMed ID: 28699662	2018
Computational discovery and experimental verification of farnesoid X receptor agonist auraptene to protect against cholestatic liver injury. Biochemical pharmacology\| PubMed ID: 28987596	2017
OAT1 and OAT3 also mediate the drug-drug interaction between piperacillin and tazobactam. International journal of pharmaceutics\| PubMed ID: 29277663	2018
Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway. Pharmacological research\| PubMed ID: 29284152	2018
Scutellarin ameliorates nonalcoholic fatty liver disease through the PPARγ/PGC-1α-Nrf2 pathway. Free radical research\| PubMed ID: 29400110	2018
Protective effects of yangonin from an edible botanical Kava against lithocholic acid-induced cholestasis and hepatotoxicity. European journal of pharmacology\| PubMed ID: 29427579	2018
P-gp is involved in the intestinal absorption and biliary excretion of afatinib in vitro and in rats. Pharmacological reports : PR\| PubMed ID: 29475007	2018
Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro. Toxicology and applied pharmacology\| PubMed ID: 29660435	2018
Icariin promotes stable chondrogenic differentiation of bone marrow mesenchymal stem cells in self‑assembling peptide nanofiber hydrogel scaffolds. Molecular medicine reports\| PubMed ID: 29693145	2018
Puerarin improves methotrexate-induced renal damage by up-regulating renal expression of Oat1 and Oat3 in vivo and in vitro. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 29710508	2018
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor. Food & function\| PubMed ID: 29721568	2018
Protective effects of ginsenoside Rg1 against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice through inhibiting toll-like receptor 4 signaling pathway. International immunopharmacology\| PubMed ID: 29902710	2018
MicroRNA-351-5p aggravates intestinal ischaemia/reperfusion injury through the targeting of MAPK13 and Sirtuin-6. British journal of pharmacology\| PubMed ID: 29952043	2018
JBP485 attenuates vancomycin-induced nephrotoxicity by regulating the expressions of organic anion transporter (Oat) 1, Oat3, organic cation transporter 2 (Oct2), multidrug resistance-associ... Toxicology letters\| PubMed ID: 29964132	2018
Hepatoprotective effect of ginsenoside Rg1 from Panax ginseng on carbon tetrachloride-induced acute liver injury by activating Nrf2 signaling pathway in mice. Environmental toxicology\| PubMed ID: 29964319	2018
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 29975924	2018
Novel amino acid-substituted diphenylpyrimidine derivatives as potent BTK inhibitors against B cell lymphoma cell lines. Bioorganic & medicinal chemistry\| PubMed ID: 30006143	2018
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro. Regulatory toxicology and pharmacology : RTP\| PubMed ID: 30030101	2018
Structural optimization of diphenylpyrimidine scaffold as potent and selective epidermal growth factor receptor inhibitors against L858R/T790M resistance mutation in nonsmall cell lung cance... Chemical biology & drug design\| PubMed ID: 30030903	2018
Hepatoprotective effect of rhein against methotrexate-induced liver toxicity. European journal of pharmacology\| PubMed ID: 30031796	2018
Activating the PGC-1/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link. Oxidative medicine and cellular longevity\| PubMed ID: 30046372	2018
Pharmacokinetic changes of cefdinir and cefditoren and its molecular mechanisms in acute kidney injury in rats. The Journal of pharmacy and pharmacology\| PubMed ID: 30047127	2018
Involvement of organic cation transporter 2 in the metformin-associated increased lactate levels caused by contrast-induced nephropathy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 30119251	2018
Combination of dihydromyricetin and ondansetron strengthens antiproliferative efficiency of adriamycin in K562/ADR through downregulation of SORCIN: A new strategy of inhibiting P-glycoprote... Journal of cellular physiology\| PubMed ID: 30171603	2019
Luteolin attenuates glucocorticoid-induced osteoporosis by regulating ERK/Lrp-5/GSK-3β signaling pathway in vivo and in vitro. Journal of cellular physiology\| PubMed ID: 30192012	2019
Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells. Inflammation\| PubMed ID: 30315526	2019
Protective effects of dioscin against cartilage destruction in a monosodium iodoacetate (MIA)-indcued osteoarthritis rat model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 30372803	2018
Targeting P-Glycoprotein: Nelfinavir Reverses Adriamycin Resistance in K562/ADR Cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 30497065	2018
miR-125a-5p ameliorates hepatic glycolipid metabolism disorder in type 2 diabetes mellitus through targeting of STAT3. Theranostics\| PubMed ID: 30555566	2018
Resveratrol enhances the protective effects of JBP485 against indomethacin-induced rat intestinal damage in vivo and vitro through up-regulating oligopeptide transporter 1 (Pept1). Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 30590313	2019
Yangonin protects against non-alcoholic fatty liver disease through farnesoid X receptor. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 30668392	2019
Facile synthesis of fluorescent carbon dots from Prunus cerasifera fruits for fluorescent ink, Fe ion detection and cell imaging. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy\| PubMed ID: 30703711	2019
Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage. British journal of pharmacology\| PubMed ID: 30710454	2019
Rosmarinic acid exerts an antagonistic effect on vascular calcification by regulating the Nrf2 signalling pathway. Free radical research\| PubMed ID: 30864863	2019
Scutellarin exerts protective effects against atherosclerosis in rats by regulating the Hippo-FOXO3A and PI3K/AKT signaling pathways. Journal of cellular physiology\| PubMed ID: 30891776	2019
Hepatoprotection of auraptene from the peels of citrus fruits against 17α-ethinylestradiol-induced cholestasis in mice by activating farnesoid X receptor. Food & function\| PubMed ID: 31210195	2019
An interspecies study of lipid profiles and atherosclerosis in familial hypercholesterolemia animal models with low-density lipoprotein receptor deficiency. American journal of translational research\| PubMed ID: 31217881	2019
Yangonin protects against estrogen-induced cholestasis in a farnesoid X receptor-dependent manner. European journal of pharmacology\| PubMed ID: 31220436	2019
Catalpol alleviates adriamycin-induced nephropathy by activating the SIRT1 signalling pathway in vivo and in vitro. British journal of pharmacology\| PubMed ID: 31378931	2019
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation... Pharmacological research\| PubMed ID: 31449974	2019
Hepatoprotection of yangonin against hepatic fibrosis in mice via farnesoid X receptor activation. International immunopharmacology\| PubMed ID: 31450152	2019
Organic anion transporters and PI3K-AKT-mTOR pathway mediate the synergistic anticancer effect of pemetrexed and rhein. Journal of cellular physiology\| PubMed ID: 31587272	2020
Cilastatin protects against imipenem-induced nephrotoxicity inhibition of renal organic anion transporters (OATs). Acta pharmaceutica Sinica. B\| PubMed ID: 31649848	2019
Corrigendum to "Dioscin attenuates renal ischemia/reperfusion injury by inhibiting theTLR4/MyD88 signaling pathway via up-regulation of HSP70" [Pharmacol. Res. 100 (2015) 341-352]. Pharmacological research\| PubMed ID: 31699473	2019
Biomineralized Gd O @HSA Nanoparticles as a Versatile Platform for Dual-Modal Imaging and Chemo-Phototherapy-Synergized Tumor Ablation. Advanced healthcare materials\| PubMed ID: 31738019	2019
Corrigendum to "Dioscin reduces ovariectomy-induced bone loss by enhancing osteoblastogenesis and inhibiting osteoclastogenesis" [Pharmacol. Res. 108 (2016) 90-101]. Pharmacological research\| PubMed ID: 31780339	2020
Synthesis and biological activity of thieno[3,2-d]pyrimidines as potent JAK3 inhibitors for the treatment of idiopathic pulmonary fibrosis. Bioorganic & medicinal chemistry\| PubMed ID: 31866272	2020
Corrigendum to "Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress... Pharmacological research\| PubMed ID: 31926782	2020
Protective effect of cilastatin against diclofenac-induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters. British journal of pharmacology\| PubMed ID: 32000294	2020
Targeting of miR-96-5p by catalpol ameliorates oxidative stress and hepatic steatosis in LDLr-/- mice via p66shc/cytochrome C cascade. Aging\| PubMed ID: 32023549	2020
Piperacillin enhances the inhibitory effect of tazobactam on β-lactamase through inhibition of organic anion transporter 1/3 in rats. Asian journal of pharmaceutical sciences\| PubMed ID: 32104494	2019
Macrophage-derived MMP-9 enhances the progression of atherosclerotic lesions and vascular calcification in transgenic rabbits. Journal of cellular and molecular medicine\| PubMed ID: 32126159	2020
A Review of the Anti-Inflammatory Effects of Rosmarinic Acid on Inflammatory Diseases. Frontiers in pharmacology\| PubMed ID: 32184728	2020
Molecular pharmacokinetic mechanism of the drug-drug interaction between genistein and repaglinide mediated by P-gp. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 32187961	2020
Organic anion transporters also mediate the drug-drug interaction between imipenem and cilastatin. Asian journal of pharmaceutical sciences\| PubMed ID: 32373203	2020
Targeting renal OATs to develop renal protective agent from traditional Chinese medicines: Protective effect of Apigenin against Imipenem-induced nephrotoxicity. Phytotherapy research : PTR\| PubMed ID: 32468621	2020
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism. Frontiers in pharmacology\| PubMed ID: 32792941	2020
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway. Phytotherapy research : PTR\| PubMed ID: 32914480	2021
Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis. European journal of pharmacology\| PubMed ID: 33068587	2021
Author Correction: Potent effects of dioscin against obesity in mice. Scientific reports\| PubMed ID: 33093537	2020
Puerarin sensitized K562/ADR cells by inhibiting NF-κB pathway and inducing autophagy. Phytotherapy research : PTR\| PubMed ID: 33141989	2021
Phosphocreatine Promotes Osteoblastic Activities in HO-Induced MC3T3-E1 Cells by Regulating SIRT1/FOXO1/PGC-1α Signaling Pathway. Current pharmaceutical biotechnology\| PubMed ID: 33198615	2021
Synthesis and biological activity of imidazole group-substituted arylaminopyrimidines (IAAPs) as potent BTK inhibitors against B-cell lymphoma and AML. Bioorganic chemistry\| PubMed ID: 33272709	2021
Identifying the Dominant Contribution of Human Cytochrome P450 2J2 to the Metabolism of Rivaroxaban, an Oral Anticoagulant. Cardiovascular drugs and therapy\| PubMed ID: 33411110	2022
Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties. Oxidative medicine and cellular longevity\| PubMed ID: 33510841	2021
Comparison of the Inhibitory Effects of Clotrimazole and Ketoconazole against Human Carboxylesterase 2. Current drug metabolism\| PubMed ID: 33568030	2021
Luteolin ameliorates LPS-induced acute liver injury by inhibiting TXNIP-NLRP3 inflammasome in mice. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 34044253	2021
Synthesis and biological evaluation of selenogefitinib for reducing bleomycin-induced pulmonary fibrosis. Bioorganic & medicinal chemistry letters\| PubMed ID: 34216747	2021
Noncovalent EGFR T790M/L858R inhibitors based on diphenylpyrimidine scaffold: Design, synthesis, and bioactivity evaluation for the treatment of NSCLC. European journal of medicinal chemistry\| PubMed ID: 34218082	2021
Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 34304130	2021
Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway. Pharmaceutical biology\| PubMed ID: 34403325	2021
In vitro Measurement and In vivo Prediction of Time-Dependent Inhibitory Effects of Three Tyrosine Kinase Inhibitors on CYP3A Activity. Current drug metabolism\| PubMed ID: 34473615	2021
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response. International immunopharmacology\| PubMed ID: 34555641	2021
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 34785106	2022
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease. Phytotherapy research : PTR\| PubMed ID: 35041255	2022