There are several differences between the right and left ventricles. However, the pathophysiology of right ventricular infarction (RVI) has not been clarified. In the present protocol, a reproducible method for RVI mouse model generation is introduced, which may provide a means to explain the mechanism of RVI.
Liao, R., He, M., Hu, D., Gong, C., Du, H., Lin, H., Sun, H. Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice. J. Vis. Exp. (180), e63508, doi:10.3791/63508 (2022).