Jonathan P. Mochel

Jonathan P. Mochel

Department of Biomedical Sciences, Iowa State University

Affiliated withIowa State University3D Health Solutions Inc.

Research Area

Biography

Dr. Jon Mochel obtained his Veterinary Medical Degree from the National Veterinary School of Alfort. He completed his Doctorate studying Neurosciences in collaboration with the College de France and received the Silver Medal from Paris XII for his work. Dr. Mochel holds a MS in Pharmacology and Pharmacokinetics and is a Diplomate of the European College of Veterinary Pharmacology and Toxicology (ECVPT). He completed his Ph.D at Leiden University, with a focus on the mathematical modeling of the renin-angiotensin system for cardiovascular diseases. He is a founder of the Animal Health Modeling & Simulation Society which aims at promoting the dissemination of mathematical modeling in Veterinary Sciences. Dr. Mochel is an Associate Professor in the Department of Biomedical Sciences at Iowa State University and a Fellow of the American Academy of Veterinary Pharmacology and Therapeutics and an ad hoc Study Section Reviewer for the US National Science Foundation, the UK Medical Research Council and the CNRS/INSERM ATIP-Avenir Program. He is currently the President Elect of the European Association of Veterinary Pharmacology and Toxicology. His research pertains to the analysis of clinical data obtained from spontaneous animal models of human diseases to bridge the knowledge gap between experimental models and patients. He has authored more than 100 peer-reviewed publications in select biomedical journals and is the co-founder of LifEngine Animal Health, a Y Combinator company developing gene editing solutions for canine oncology, and 3D Health Solutions, a platform for efficient drug screening in pharmaceutical research.

JoVE Journal Publications

ArticleTotal : 2
Year
Standardization and Maintenance of 3D Canine Hepatic and Intestinal Organoid Cultures for Use in Biomedical Research
Publication title

Cited by 32

2022
2022

Other Publications

Article
Year
Tear fluid collection in dogs and cats using ophthalmic sponges.

Veterinary ophthalmology| PubMed ID: 28845579

2018
2018
Impact of Flow Rate, Collection Devices, and Extraction Methods on Tear Concentrations Following Oral Administration of Doxycycline in Dogs and Cats.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics| PubMed ID: 29708819

2018
2018
2018
2018
2019
2019
Sacubitril/valsartan (LCZ696) significantly reduces aldosterone and increases cGMP circulating levels in a canine model of RAAS activation.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences| PubMed ID: 30508581

2019
2019
Optimal Scheduling of Bevacizumab and Pemetrexed/Cisplatin Dosing in Non-Small Cell Lung Cancer.

CPT: pharmacometrics & systems pharmacology| PubMed ID: 31004380

2019
Tear Fluid Pharmacokinetics Following Oral Prednisone Administration in Dogs With and Without Conjunctivitis.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics| PubMed ID: 31070497

2019
2019
2019
2019
Nonlinear mixed-effects pharmacokinetic modeling of the novel COX-2 selective inhibitor vitacoxib in dogs.

Journal of veterinary pharmacology and therapeutics| PubMed ID: 31369157

2019
Fluorophotometric Assessment of Tear Volume and Turnover Rate in Healthy Dogs and Cats.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics| PubMed ID: 31381493

2019
2019
2020
2019
2020
2019
2019
2019
2020
2020
2020
2020
CSF glucose tracks regional tau progression based on Alzheimer's disease risk factors.

Alzheimer's & dementia (New York, N. Y.)| PubMed ID: 32864418

2020
2020
2021
2020
2020
2020
2020
2020
2020
2020
2021
2021
2021
Effect of prazosin on feline recurrent urethral obstruction.

Journal of feline medicine and surgery| PubMed ID: 33749375

2021
2021
2021
2021
2021
2021
2021
2021
2021
2021
Current diagnostics for chronic enteropathies in dogs.

Veterinary clinical pathology| PubMed ID: 34699081

2022
2021