Fanxin Long

Fanxin Long

Translational Research Program of Pediatric Orthopedics, The Children's Hospital of Philadelphia

Affiliated withThe Children's Hospital of Philadelphia

Research Area

Biography

Dr. Long earned his doctorate in developmental biology from Tufts University, and completed postdoctoral training at Harvard University. He received a master’s degree in biochemistry and molecular biology from the University of California, Santa Barbara, and a bachelor’s degree in cell biology from Peking University. Dr. Long began his independent research at Washington University School of Medicine in St. Louis, and served there as Professor of Medicine, Developmental Biology and Orthopedic Surgery until 2018 when he was appointed William Wikoff Smith Endowed Chair in Pediatric Genomic Research at the Children’s Hospital of Philadelphia. He currently also serves as Professor of Orthopedic Surgery at University of Pennsylvania. Dr. Long served as program co-chair for American Society of Bone and Mineral Diseases, and chair for Gordon Conference on Bones and Teeth. He currently serves as consulting editor for Journal of Clinical Investigation and associate editor for PLoS Genetics.

In his research, Dr. Long seeks to understand the fundamental mechanisms underlying normal skeletal biology and the pathophysiology of bone diseases. His group has made major contributions to the understanding of Hh, Wnt and Notch signaling in skeletal development and homeostasis. They also pioneered the studies of osteogenic signals in regulating cellular metabolism.

JoVE Journal Publications

ArticleTotal : 1
Year
Assessing Energy Substrate Oxidation <em>In Vitro</em> with <sup>14</sup>CO<sub>2</sub> Trapping
Publication title

Cited by 2

2022

Other Publications

Article
Year
Glucose metabolism induced by Bmp signaling is essential for murine skeletal development.

Nature communications| PubMed ID: 30446646

2018
2019
2020
2020
2020
The Amino Acid Sensor Eif2ak4/GCN2 Is Required for Proliferation of Osteoblast Progenitors in Mice.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research| PubMed ID: 32453500

2020
Both aerobic glycolysis and mitochondrial respiration are required for osteoclast differentiation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology| PubMed ID: 32627870

2020
2020
2021
2021
2021