Hanbin Mao

Department of Chemistry & Biochemistry, Kent State University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2022

Other Publications

Article	Year
ILPR G-quadruplexes formed in seconds demonstrate high mechanical stabilities. Journal of the American Chemical Society\| PubMed ID: 19154151	2009
Direct experimental evidence for quadruplex-quadruplex interaction within the human ILPR. Nucleic acids research\| PubMed ID: 19324891	2009
ILPR repeats adopt diverse G-quadruplex conformations that determine insulin binding. Biopolymers\| PubMed ID: 19688813	2010
Coexistence of an ILPR i-motif and a partially folded structure with comparable mechanical stability revealed at the single-molecule level. Journal of the American Chemical Society\| PubMed ID: 20545340	2010
Detection of single nucleotide polymorphism using tension-dependent stochastic behavior of a single-molecule template. Journal of the American Chemical Society\| PubMed ID: 21639132	2011
A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands. Nature chemistry\| PubMed ID: 21941250	2011
Intramolecular folding in three tandem guanine repeats of human telomeric DNA. Chemical communications (Cambridge, England)\| PubMed ID: 22234724	2012
Tertiary DNA Structure in the Single-Stranded hTERT Promoter Fragment Unfolds and Refolds by Parallel Pathways via Cooperative or Sequential Events. Journal of the American Chemical Society\| PubMed ID: 22372563	2012
Single-molecule measurements of the binding between small molecules and DNA aptamers. Analytical chemistry\| PubMed ID: 22702719	2012
G-quadruplex and i-motif are mutually exclusive in ILPR double-stranded DNA. Biophysical journal\| PubMed ID: 22713573	2012
Intramolecular folding in human ILPR fragment with three C-rich repeats. PloS one\| PubMed ID: 22761750	2012
Click chemistry assisted single-molecule fingerprinting reveals a 3D biomolecular folding funnel. Journal of the American Chemical Society\| PubMed ID: 22799529	2012
Long-Loop G-Quadruplexes are Misfolded Population Minorities with Fast Transition Kinetics in Human Telomeric Sequences. Journal of the American Chemical Society\| PubMed ID: 23327686	2013
Non-B DNA structures show diverse conformations and complex transition kinetics comparable to RNA or proteins--a perspective from mechanical unfolding and refolding experiments. Chemical record (New York, N.Y.)\| PubMed ID: 23389854	2013
Structural and mechanical properties of individual human telomeric G-quadruplexes in molecularly crowded solutions. Nucleic acids research\| PubMed ID: 23396442	2013
Mechanochemical properties of individual human telomeric RNA (TERRA) G-quadruplexes. Chembiochem : a European journal of chemical biology\| PubMed ID: 24038851	2013
Controlled particle collision leads to direct observation of docking and fusion of lipid droplets in an optical trap. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 24447288	2014
Yoctoliter thermometry for single-molecule investigations: a generic bead-on-a-tip temperature-control module. Angewandte Chemie (International ed. in English)\| PubMed ID: 24596309	2014
Molecular population dynamics of DNA structures in a bcl-2 promoter sequence is regulated by small molecules and the transcription factor hnRNP LL. Nucleic acids research\| PubMed ID: 24609386	2014
Nascent RNA transcripts facilitate the formation of G-quadruplexes. Nucleic acids research\| PubMed ID: 24829453	2014
Single-molecule mechanochemical sensing using DNA origami nanostructures. Angewandte Chemie (International ed. in English)\| PubMed ID: 24931175	2014
Intermediates stabilized by tryptophan pairs exist in trpzip Beta-hairpins. Biochemistry\| PubMed ID: 25164564	2014
Quantification of topological coupling between DNA superhelicity and G-quadruplex formation. Journal of the American Chemical Society\| PubMed ID: 25216033	2014
Direct quantification of loop interaction and π-π stacking for G-quadruplex stability at the submolecular level. Journal of the American Chemical Society\| PubMed ID: 25296000	2014
Dual binding of an antibody and a small molecule increases the stability of TERRA G-quadruplex. Angewandte Chemie (International ed. in English)\| PubMed ID: 25421962	2015
Interaction of G-quadruplexes in the full-length 3' human telomeric overhang. Journal of the American Chemical Society\| PubMed ID: 25438191	2014
Dissecting cooperative communications in a protein with a high-throughput single-molecule scalpel. Chemphyschem : a European journal of chemical physics and physical chemistry\| PubMed ID: 25470139	2015
Divalent cations and molecular crowding buffers stabilize G-triplex at physiologically relevant temperatures. Scientific reports\| PubMed ID: 25787838	2015
Mechanochemical Sensing: A Biomimetic Sensing Strategy. Chemphyschem : a European journal of chemical physics and physical chemistry\| PubMed ID: 25916512	2015
A molecular tuning fork in single-molecule mechanochemical sensing. Angewandte Chemie (International ed. in English)\| PubMed ID: 25960021	2015
Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex. Angewandte Chemie (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 26300569	2015
Exploded view of higher order G-quadruplex structures through click-chemistry assisted single-molecule mechanical unfolding. Nucleic acids research\| PubMed ID: 26626151	2016
Mutually Exclusive Formation of G-Quadruplex and i-Motif Is a General Phenomenon Governed by Steric Hindrance in Duplex DNA. Biochemistry\| PubMed ID: 27027664	2016
Mechanical properties of DNA origami nanoassemblies are determined by Holliday junction mechanophores. Nucleic acids research\| PubMed ID: 27387283	2016
Mechanochemical Sensing of Single and Few Hg(II) Ions Using Polyvalent Principles. Analytical chemistry\| PubMed ID: 27618437	2016
A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters. Journal of the American Chemical Society\| PubMed ID: 27643954	2016
A Mechanosensor Mechanism Controls the G-Quadruplex/i-Motif Molecular Switch in the MYC Promoter NHE III. Journal of the American Chemical Society\| PubMed ID: 27669098	2016
Confined space facilitates G-quadruplex formation. Nature nanotechnology\| PubMed ID: 28346457	2017
Adaptive and Specific Recognition of Telomeric G-Quadruplexes via Polyvalency Induced Unstacking of Binding Units. Journal of the American Chemical Society\| PubMed ID: 28505453	2017
Quantification of Chemical and Mechanical Effects on the Formation of the G-Quadruplex and i-Motif in Duplex DNA. Biochemistry\| PubMed ID: 28738141	2017
Single-Molecule Mechanochemical pH Sensing Revealing the Proximity Effect of Hydroniums Generated by an Alkaline Phosphatase. Analytical chemistry\| PubMed ID: 29285923	2018
A New Concentration Jump Strategy Reveals the Lifetime of i-Motif at Physiological pH without Force. Analytical chemistry\| PubMed ID: 29400441	2018
Mechanical Cooperativity in DNA Cruciform Structures. Chemphyschem : a European journal of chemical physics and physical chemistry\| PubMed ID: 29992736	2018
Decreased water activity in nanoconfinement contributes to the folding of G-quadruplex and i-motif structures. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30181280	2018
Binding of a Telomestatin Derivative Changes the Mechanical Anisotropy of a Human Telomeric G-Quadruplex. Angewandte Chemie (International ed. in English)\| PubMed ID: 30476359	2019
Random Formation of G-Quadruplexes in the Full-Length Human Telomere Overhangs Leads to a Kinetic Folding Pattern with Targetable Vacant G-Tracts. Biochemistry\| PubMed ID: 30480434	2018
Submolecular dissection reveals strong and specific binding of polyamide-pyridostatin conjugates to human telomere interface. Nucleic acids research\| PubMed ID: 30820532	2019
Single-Molecule Mechanochemical Sensing Using DNA Origami Nanostructures. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 31309481	2019
Single-Molecule Investigations of G-Quadruplex. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 31444756	2019
Single-Molecule Topochemical Analyses for Large-Scale Multiplexing Tasks. Analytical chemistry\| PubMed ID: 31553880	2019
Chaperone-Assisted Host-Guest Interactions Revealed by Single-Molecule Force Spectroscopy. Journal of the American Chemical Society\| PubMed ID: 31679339	2019
Duplex DNA Is Weakened in Nanoconfinement. Journal of the American Chemical Society\| PubMed ID: 32383870	2020
Detecting the Coronavirus (COVID-19). ACS sensors\| PubMed ID: 32627534	2020
A poly(thymine)-melamine duplex for the assembly of DNA nanomaterials. Nature materials\| PubMed ID: 32661383	2020
Ensemble Sensing Using Single-Molecule DNA Copolymers. Analytical chemistry\| PubMed ID: 32829637	2020
Cooperative Heteroligand Interaction with G-Quadruplexes Shows Evidence of Allosteric Binding. Biochemistry\| PubMed ID: 32833433	2020
Chemo-Mechanical Modulation of Cell Motions Using DNA Nanosprings. Bioconjugate chemistry\| PubMed ID: 33475341	2021
Mechanochemical properties of DNA origami nanosprings revealed by force jumps in optical tweezers. Nanoscale\| PubMed ID: 33908965	2021
Mechanical unfolding of ensemble biomolecular structures by shear force. Chemical science\| PubMed ID: 34377405	2021
DNA origami nano-mechanics. Chemical Society reviews\| PubMed ID: 34499072	2021
Measurement of Single-Molecule Forces in Cholesterol and Cyclodextrin Host-Guest Complexes. The journal of physical chemistry. B\| PubMed ID: 34523939	2021
Correction: DNA origami nano-mechanics. Chemical Society reviews\| PubMed ID: 34549206	2021
Direct Measurement of Intermolecular Mechanical Force for Nonspecific Interactions between Small Molecules. The journal of physical chemistry letters\| PubMed ID: 34780182	2021
Chirality transmission in macromolecular domains. Nature communications\| PubMed ID: 35013247	2022
Dissection of nanoconfinement and proximity effects on the binding events in DNA origami nanocavity. Nucleic acids research\| PubMed ID: 35037040	2022
Small Molecules Modulate Liquid-to-Solid Transitions in Phase-Separated Tau Condensates. Angewandte Chemie (International ed. in English)\| PubMed ID: 35320624	2022
Single-Molecule Mechanochemical Sensing. Accounts of chemical research\| PubMed ID: 35420417	2022
Single-molecule displacement assay reveals strong binding of polyvalent dendrimer ligands to telomeric G-quadruplex. Analytical biochemistry\| PubMed ID: 35500657	2022
Short LNA-modified oligonucleotide probes as efficient disruptors of DNA G-quadruplexes. Nucleic acids research\| PubMed ID: 35801856	2022