Nikolai Slavov

Nikolai Slavov

Department of Bioengineering, Northeastern University

Affiliated withNortheastern UniversityNortheastern University

Research Area

Biography

Nikolai Slavov is an Allen Distinguished Investigator and associate professor at Northeastern University in the Bioengineering Department and Barnett Institute. His lab has pioneered several multiplexed experimental methods for quantifying proteins in single cells and is developing new computational methods for analyzing and understanding single-cell protein data. He organizes the annual single-cell proteomics conference (single-cell.net/) and contributes to organizing other leading conferences, including HUPO, Oxford Global, NeurIPS, and others. The Slavov lab obtained direct evidence for a new regulatory mechanism of protein synthesis (ribosome specialization) and continues to drive research in this emerging field. Research from the Slavov lab has been recognized and supported by many prestigious awards, including the Allen Distinguished Investigator Award, the NIH Director’s Award, the Chan Zuckerberg Initiative, and iAward from Sanofi. Nikolai Slavov received BS from MIT in 2004, a PhD from Princeton University (Botstein laboratory) in 2010 and conducted postdoctoral research in the van Oudenaarden laboratory at MIT.

JoVE Journal Publications

ArticleTotal : 1
Year
Single-Cell Proteomics Preparation for Mass Spectrometry Analysis Using Freeze-Heat Lysis and an Isobaric Carrier
Publication title

Cited by 10

2022

Other Publications

Article
Year
Voices in methods development.

Nature methods| PubMed ID: 31562479

2019
Making the most of peer review.

eLife| PubMed ID: 26559758

2015
2015
2016
2016
Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-β Synthesis Induced by Lipopolysaccharide.

Journal of immunology (Baltimore, Md. : 1950)| PubMed ID: 28461567

2017
Post-transcriptional regulation across human tissues.

PLoS computational biology| PubMed ID: 28481885

2017
Transformative Opportunities for Single-Cell Proteomics.

Journal of proteome research| PubMed ID: 29945450

2018
Single cell protein analysis for systems biology.

Essays in biochemistry| PubMed ID: 30072488

2018
Quantifying Homologous Proteins and Proteoforms.

Molecular & cellular proteomics : MCP| PubMed ID: 30282776

2019
2018
Ribosome Stoichiometry: From Form to Function.

Trends in biochemical sciences| PubMed ID: 30473427

2019
Approaches for Studying Ribosome Specialization.

Trends in biochemical sciences| PubMed ID: 30792028

2019
DO-MS: Data-Driven Optimization of Mass Spectrometry Methods.

Journal of proteome research| PubMed ID: 31081635

2019
DART-ID increases single-cell proteome coverage.

PLoS computational biology| PubMed ID: 31260443

2019
Unpicking the proteome in single cells.

Science (New York, N.Y.)| PubMed ID: 32001644

2020
Single-cell protein analysis by mass spectrometry.

Current opinion in chemical biology| PubMed ID: 32599342

2021
2020
2021
2021
Voices of biotech research.

Nature biotechnology| PubMed ID: 33692517

2021
Increasing proteomics throughput.

Nature biotechnology| PubMed ID: 33767394

2021
Measuring Protein Shapes in Living Cells.

Journal of proteome research| PubMed ID: 33988997

2021
Driving Single Cell Proteomics Forward with Innovation.

Journal of proteome research| PubMed ID: 34597050

2021
Multiplexed single-cell proteomics using SCoPE2.

Nature protocols| PubMed ID: 34716448

2021
2021
Comprehensive Identification of Regulatory Protein Networks.

Journal of proteome research| PubMed ID: 34736325

2021
Scaling Up Single-Cell Proteomics.

Molecular & cellular proteomics : MCP| PubMed ID: 34808355

2022
2022
2022
Beyond Protein Sequence: Protein Isomerization in Alzheimer's Disease.

Journal of proteome research| PubMed ID: 35114789

2022
New Views of Old Proteins: Clarifying the Enigmatic Proteome.

Molecular & cellular proteomics : MCP| PubMed ID: 35654359

2022
Increasing the throughput of sensitive proteomics by plexDIA.

Nature biotechnology| PubMed ID: 35835881

2022