ER

Edwin Roger Parra

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center

Affiliated withThe University of Texas MD Anderson Cancer Center

Research Area

Biography

I am an Associate Professor and Director of the Multiplex Immunofluorescence and Image Analysis Laboratory in the Department of Translational Molecular Pathology at The University of Texas MD Anderson Cancer Center. I obtained my M.D. from the University of Mayor de San Andres, Bolivia, and I finished my Residence in Pathology at Sao Paulo Medical School, Brazil. Then I obtained my Ph.D. and my first Postdoctoral Fellow at the same University and my second Postdoctoral Fellow at The University of Texas, MD Anderson Cancer Center. I was promoted to Research Scientist and, in a short period, to Assistant Professor at the same University. I am a pathologist with a strong background in surgical pathology and research. My main interest is tissue immune profiling and elucidating the mechanisms involved in the pathogenesis and progression of cancer, particularly lung cancer. I aimed to accomplish this objective by applying various staining techniques and imaging platforms, including multiplex immunofluorescence and RNAscope, and high-plex imaging platforms, such as CO-Detection by indEXing and multiplexed ion beam imaging. I am also interested in studying the immune response to immunotherapy in longitudinal cancer studies to discover and characterize new biomarkers for future treatment approaches. I have over 15 years of research experience teaching technicians, graduate students, and doctoral and postdoctoral fellows. I also have extensive experience in performing standard laboratory techniques. I authored over 100 articles on lung cancer, interstitial lung diseases in human and animal models, and immune profiling using the various image analysis–based methodologies described above. I have also authored several abstracts and presentations for national and international scientific meetings, book chapters, and reports on pulmonary pathology and other medical topics.

JoVE Journal Publications

ArticleTotal : 2
Year
Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples
Publication title

Cited by 2

2022
2023

Other Publications

Article
Year
4-1BB Agonist Focuses CD8(+) Tumor-Infiltrating T-Cell Growth into a Distinct Repertoire Capable of Tumor Recognition in Pancreatic Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research| PubMed ID: 28947567

2017
2017
Immunohistochemical and Image Analysis-Based Study Shows That Several Immune Checkpoints are Co-expressed in Non-Small Cell Lung Carcinoma Tumors.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer| PubMed ID: 29526824

2018
2018
2018
2018
2019
2019
B7-H3 Expression in Merkel Cell Carcinoma-Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density.

Clinical cancer research : an official journal of the American Association for Cancer Research| PubMed ID: 30808776

2019
2019
2019
Multiplex Immunofluorescence Assays.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 31502166

2020
2020
2020
2020
2021
2021
2021
2021
2021
Pilot Clinical Trial of Perioperative Durvalumab and Tremelimumab in the Treatment of Resectable Colorectal Cancer Liver Metastases.

Clinical cancer research : an official journal of the American Association for Cancer Research| PubMed ID: 33811152

2021
2021
2021
2021
2021
2021
2021
2021
2021
2021
2021
Effector memory cytotoxic CD3/CD8/CD45RO T cells are predictive of good survival and a lower risk of recurrence in triple-negative breast cancer.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc| PubMed ID: 34839351

2021
2022
2022
2022
2022
2022
2022