Simon M. Hughes

Randall Centre for Cell and Molecular Biophysics, King’s College London

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2022

Other Publications

Article	Year
MyoD protein is differentially accumulated in fast and slow skeletal muscle fibres and required for normal fibre type balance in rodents. Mechanisms of development\| PubMed ID: 9076685	1997
Notochord induction of zebrafish slow muscle mediated by Sonic hedgehog. Genes & development\| PubMed ID: 9303533	1997
The role of hedgehog proteins in vertebrate slow and fast skeletal muscle patterning. Acta physiologica Scandinavica\| PubMed ID: 9715744	1998
Myogenin induces a shift of enzyme activity from glycolytic to oxidative metabolism in muscles of transgenic mice. The Journal of cell biology\| PubMed ID: 10225962	1999
Muscular expressions: profiling genes in complex tissues. Genome biology\| PubMed ID: 11790260	2001
Aging-related satellite cell differentiation defect occurs prematurely after Ski-induced muscle hypertrophy. American journal of physiology. Cell physiology\| PubMed ID: 12225986	2002
Acridine mutagenesis of zebrafish (Danio rerio). Mutation research\| PubMed ID: 12650900	2003
Intermediate filament-co-localized molecules with myosin heavy chain epitopes define distinct cellular domains in hair follicles and epidermis. BMC cell biology\| PubMed ID: 12899730	2003
Muscle differentiation: a gene for slow muscle? Current biology : CB\| PubMed ID: 15027468	2004
Hedgehog regulation of superficial slow muscle fibres in Xenopus and the evolution of tetrapod trunk myogenesis. Development (Cambridge, England)\| PubMed ID: 15201218	2004
Hedgehog can drive terminal differentiation of amniote slow skeletal muscle. BMC developmental biology\| PubMed ID: 15238161	2004
The kinase domain of titin controls muscle gene expression and protein turnover. Science (New York, N.Y.)\| PubMed ID: 15802564	2005
Fgf8 drives myogenic progression of a novel lateral fast muscle fibre population in zebrafish. Development (Cambridge, England)\| PubMed ID: 16120642	2005
Evidence that satellite cell decrement contributes to preferential decline in nuclear number from large fibres during murine age-related muscle atrophy. Journal of cell science\| PubMed ID: 16219688	2005
Comparison of neurolin (ALCAM) and neurolin-like cell adhesion molecule (NLCAM) expression in zebrafish. Gene expression patterns : GEP\| PubMed ID: 16750657	2006
Signals and myogenic regulatory factors restrict pax3 and pax7 expression to dermomyotome-like tissue in zebrafish. Developmental biology\| PubMed ID: 17094960	2007
The dystrotelin, dystrophin and dystrobrevin superfamily: new paralogues and old isoforms. BMC genomics\| PubMed ID: 17233888	2007
Mef2s are required for thick filament formation in nascent muscle fibres. Development (Cambridge, England)\| PubMed ID: 17537787	2007
Mrf4 (myf6) is dynamically expressed in differentiated zebrafish skeletal muscle. Gene expression patterns : GEP\| PubMed ID: 17638597	2007
Vestigial-like-2b (VITO-1b) and Tead-3a (Tef-5a) expression in zebrafish skeletal muscle, brain and notochord. Gene expression patterns : GEP\| PubMed ID: 17916448	2007
Dystrobrevin and dystrophin family gene expression in zebrafish. Gene expression patterns : GEP\| PubMed ID: 18042440	2008
MyoD- and nerve-dependent maintenance of MyoD expression in mature muscle fibres acts through the DRR/PRR element. BMC developmental biology\| PubMed ID: 18215268	2008
Development of mandibular, hyoid and hypobranchial muscles in the zebrafish: homologies and evolution of these muscles within bony fishes and tetrapods. BMC developmental biology\| PubMed ID: 18307809	2008
Sequential actions of Pax3 and Pax7 drive xanthophore development in zebrafish neural crest. Developmental biology\| PubMed ID: 18417109	2008
Nerve-dependent changes in skeletal muscle myosin heavy chain after experimental denervation and cross-reinnervation and in a demyelinating mouse model of Charcot-Marie-Tooth disease type 1A... Muscle & nerve\| PubMed ID: 19016545	2008
Wnt signaling promotes AChR aggregation at the neuromuscular synapse in collaboration with agrin. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19020093	2008
Differential requirements for myogenic regulatory factors distinguish medial and lateral somitic, cranial and fin muscle fibre populations. Development (Cambridge, England)\| PubMed ID: 19141670	2009
Other model organisms for sarcomeric muscle diseases. Advances in experimental medicine and biology\| PubMed ID: 19181102	2008
Cdkn1c drives muscle differentiation through a positive feedback loop with Myod. Developmental biology\| PubMed ID: 21147088	2011
Defective cranial skeletal development, larval lethality and haploinsufficiency in Myod mutant zebrafish. Developmental biology\| PubMed ID: 21798255	2011
Zebrafish Mef2ca and Mef2cb are essential for both first and second heart field cardiomyocyte differentiation. Developmental biology\| PubMed ID: 22750409	2012
Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion. Development (Cambridge, England)\| PubMed ID: 23760954	2013
Notch signalling is required for the formation of structurally stable muscle fibres in zebrafish. PloS one\| PubMed ID: 23840804	2013
eIF4EBP3L acts as a gatekeeper of TORC1 in activity-dependent muscle growth by specifically regulating Mef2ca translational initiation. PLoS biology\| PubMed ID: 24143132	2013
Anaesthetic tricaine acts preferentially on neural voltage-gated sodium channels and fails to block directly evoked muscle contraction. PloS one\| PubMed ID: 25090007	2014
In vivo dynamics of skeletal muscle Dystrophin in zebrafish embryos revealed by improved FRAP analysis. eLife\| PubMed ID: 26459831	2015
Cellular dynamics of regeneration reveals role of two distinct Pax7 stem cell populations in larval zebrafish muscle repair. Disease models & mechanisms\| PubMed ID: 27149989	2016
The Cannabinoid Receptor Interacting Proteins 1 of zebrafish are not required for morphological development, viability or fertility. Scientific reports\| PubMed ID: 28687732	2017
CRISPR/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function. Scientific reports\| PubMed ID: 28819307	2017
Myotome adaptability confers developmental robustness to somitic myogenesis in response to fibre number alteration. Developmental biology\| PubMed ID: 28887016	2017
Mef2 and the skeletal muscle differentiation program. Seminars in cell & developmental biology\| PubMed ID: 29154822	2017
Myogenin promotes myocyte fusion to balance fibre number and size. Nature communications\| PubMed ID: 30315160	2018
Scleraxis genes are required for normal musculoskeletal development and for rib growth and mineralization in zebrafish. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 31100023	2019
EGF receptor (EGFR) inhibition promotes a slow-twitch oxidative, over a fast-twitch, muscle phenotype. Scientific reports\| PubMed ID: 31239465	2019
Maternal Larp6 controls oocyte development, chorion formation and elevation. Development (Cambridge, England)\| PubMed ID: 32054660	2020
Fgf-driven Tbx protein activities directly induce and to initiate zebrafish myogenesis. Development (Cambridge, England)\| PubMed ID: 32345657	2020
Myogenin is an essential regulator of adult myofibre growth and muscle stem cell homeostasis. eLife\| PubMed ID: 33001028	2020
Circadian regulation of muscle growth independent of locomotor activity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 33229575	2020
Mef2c factors are required for early but not late addition of cardiomyocytes to the ventricle. Developmental biology\| PubMed ID: 33245870	2021
Cellular and molecular pathways controlling muscle size in response to exercise. The FEBS journal\| PubMed ID: 33755332	2022
Knockout of zebrafish desmin genes does not cause skeletal muscle degeneration but alters calcium flux. Scientific reports\| PubMed ID: 33820917	2021
mRNP granule proteins Fmrp and Dcp1a differentially regulate mRNP complexes to contribute to control of muscle stem cell quiescence and activation. Skeletal muscle\| PubMed ID: 34238354	2021
Isolation of Myofibres and Culture of Muscle Stem Cells from Adult Zebrafish. Bio-protocol\| PubMed ID: 34604454	2021