Nicolas Servant

Institut Curie

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2022

Other Publications

Article	Year
PRC2 is dispensable for -mediated transcriptional repression. The EMBO journal\| PubMed ID: 28167697	2017
Adrenal GIPR expression and chromosome 19q13 microduplications in GIP-dependent Cushing's syndrome. JCI insight\| PubMed ID: 28931750	2017
VAMP: visualization and analysis of array-CGH, transcriptome and other molecular profiles. Bioinformatics (Oxford, England)\| PubMed ID: 16820431	2006
High-resolution mapping of DNA breakpoints to define true recurrences among ipsilateral breast cancers. Journal of the National Cancer Institute\| PubMed ID: 18159071	2008
Tumor aromatase expression as a prognostic factor for local control in young breast cancer patients after breast-conserving treatment. Breast cancer research : BCR\| PubMed ID: 19638208	2009
Multiparametric analysis of cytokine-driven human Th17 differentiation reveals a differential regulation of IL-17 and IL-22 production. Blood\| PubMed ID: 19704117	2009
Highly dynamic and sex-specific expression of microRNAs during early ES cell differentiation. PLoS genetics\| PubMed ID: 19714213	2009
LINE-1 activity in facultative heterochromatin formation during X chromosome inactivation. Cell\| PubMed ID: 20550932	2010
EMA - A R package for Easy Microarray data analysis. BMC research notes\| PubMed ID: 21047405	2010
Importance of pre-analytical steps for transcriptome and RT-qPCR analyses in the context of the phase II randomised multicentre trial REMAGUS02 of neoadjuvant chemotherapy in breast cancer p... BMC cancer\| PubMed ID: 21631949	2011
Search for a gene expression signature of breast cancer local recurrence in young women. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 22271875	2012
Deep-sequencing protocols influence the results obtained in small-RNA sequencing. PloS one\| PubMed ID: 22384282	2012
Spatial partitioning of the regulatory landscape of the X-inactivation centre. Nature\| PubMed ID: 22495304	2012
Independent transcriptional reprogramming and apoptosis induction by cisplatin. Cell cycle (Georgetown, Tex.)\| PubMed ID: 22918244	2012
HiTC: exploration of high-throughput 'C' experiments. Bioinformatics (Oxford, England)\| PubMed ID: 22923296	2012
ncPRO-seq: a tool for annotation and profiling of ncRNAs in sRNA-seq data. Bioinformatics (Oxford, England)\| PubMed ID: 23044543	2012
Designs and challenges for personalized medicine studies in oncology: focus on the SHIVA trial. Targeted oncology\| PubMed ID: 23161020	2012
Telomere crisis in kidney epithelial cells promotes the acquisition of a microRNA signature retrieved in aggressive renal cell carcinomas. Carcinogenesis\| PubMed ID: 23358853	2013
RNAi-dependent and independent control of LINE1 accumulation and mobility in mouse embryonic stem cells. PLoS genetics\| PubMed ID: 24244175	2013
Changes in the organization of the genome during the mammalian cell cycle. Genome biology\| PubMed ID: 24368000	2013
Developmental dynamics and disease potential of random monoallelic gene expression. Developmental cell\| PubMed ID: 24576422	2014
Combinatorial flexibility of cytokine function during human T helper cell differentiation. Nature communications\| PubMed ID: 24865484	2014
Bioinformatics for precision medicine in oncology: principles and application to the SHIVA clinical trial. Frontiers in genetics\| PubMed ID: 24910641	2014
[Biological network modelling and precision medicine in oncology]. Bulletin du cancer\| PubMed ID: 24966078	2014
Multi-factor data normalization enables the detection of copy number aberrations in amplicon sequencing data. Bioinformatics (Oxford, England)\| PubMed ID: 25016581	2014
Epigenomic alterations in breast carcinoma from primary tumor to locoregional recurrences. PloS one\| PubMed ID: 25098247	2014
Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation. Molecular cell\| PubMed ID: 25620564	2015
The spectrum of clinical trials aiming at personalizing medicine. Chinese clinical oncology\| PubMed ID: 25841410	2014
Combinatorial code governing cellular responses to complex stimuli. Nature communications\| PubMed ID: 25896517	2015
Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure. Nature\| PubMed ID: 25970250	2015
DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination. Genes & development\| PubMed ID: 26109049	2015
Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled ... The Lancet. Oncology\| PubMed ID: 26342236	2015
Design and statistical principles of the SHIVA trial. Chinese clinical oncology\| PubMed ID: 26408299	2015
Integration of a Radiosensitivity Molecular Signature Into the Assessment of Local Recurrence Risk in Breast Cancer. International journal of radiation oncology, biology, physics\| PubMed ID: 26461005	2015
Treatment Algorithms Based on Tumor Molecular Profiling: The Essence of Precision Medicine Trials. Journal of the National Cancer Institute\| PubMed ID: 26598514	2016
HiC-Pro: an optimized and flexible pipeline for Hi-C data processing. Genome biology\| PubMed ID: 26619908	2015
Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis. Genes & development\| PubMed ID: 26637281	2015
Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation. eLife\| PubMed ID: 26836306	2016
Xist-dependent imprinted X inactivation and the early developmental consequences of its failure. Nature structural & molecular biology\| PubMed ID: 28134930	2017
Genetic and epigenetic features direct differential efficiency of Xist-mediated silencing at X-chromosomal and autosomal locations. Nature communications\| PubMed ID: 28947736	2017
Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass. Nature communications\| PubMed ID: 29101321	2017
Exome sequencing reveals aberrant signalling pathways as hallmark of treatment-naive anal squamous cell carcinoma. Oncotarget\| PubMed ID: 29416628	2018
Revisited analysis of a SHIVA01 trial cohort using functional mutational analyses successfully predicted treatment outcome. Molecular oncology\| PubMed ID: 29464843	2018
Challenges for the implementation of high-throughput testing and liquid biopsies in personalized medicine cancer trials. Personalized medicine\| PubMed ID: 29758779	2014
Transcriptome Profiling of Single Mouse Oocytes. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29961255	2018
Effective normalization for copy number variation in Hi-C data. BMC bioinformatics\| PubMed ID: 30189838	2018
Familial breast cancer and DNA repair genes: Insights into known and novel susceptibility genes from the GENESIS study, and implications for multigene panel testing. International journal of cancer\| PubMed ID: 30303537	2019
BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation. Nature communications\| PubMed ID: 30664650	2019
Lineage tracing of Notch1-expressing cells in intestinal tumours reveals a distinct population of cancer stem cells. Scientific reports\| PubMed ID: 30696875	2019
EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30867289	2019
Clinical and genetic landscape of treatment naive cervical cancer: Alterations in PIK3CA and in epigenetic modulators associated with sub-optimal outcome. EBioMedicine\| PubMed ID: 30952619	2019
The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist. Nature genetics\| PubMed ID: 31133748	2019
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells. Nature communications\| PubMed ID: 31451685	2019
Efficacy of molecularly targeted agents given in the randomised trial SHIVA01 according to the ESMO Scale for Clinical Actionability of molecular Targets. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 31593830	2019
Improving breast cancer sensitivity to paclitaxel by increasing aneuploidy. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 31685623	2019
Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors. Cancer cell\| PubMed ID: 31708437	2019
A Conserved Noncoding Locus Regulates Random Monoallelic Xist Expression across a Topological Boundary. Molecular cell\| PubMed ID: 31759823	2020
Mechanistic Signatures of Human Papillomavirus Insertions in Anal Squamous Cell Carcinomas. Cancers\| PubMed ID: 31766658	2019
Parental-to-embryo switch of chromosome organization in early embryogenesis. Nature\| PubMed ID: 32238933	2020
Corrigendum to 'clinical and genetic landscape of treatment naive cervical cancer: Alterations in PIK3CA and in epigenetic modulators associated with sub-optimal outcome'. EBioMedicine\| PubMed ID: 32650273	2020
CD44 regulates epigenetic plasticity by mediating iron endocytosis. Nature chemistry\| PubMed ID: 32747755	2020
Bioinformatic Analysis of Single-Cell Hi-C Data from Early Mouse Embryo. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 32944918	2021
Interactive analysis of single-cell epigenomic landscapes with ChromSCape. Nature communications\| PubMed ID: 33177523	2020
Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site. British journal of cancer\| PubMed ID: 33191407	2021
SMARCA4-deficient rhabdoid tumours show intermediate molecular features between SMARCB1-deficient rhabdoid tumours and small cell carcinomas of the ovary, hypercalcaemic type. The Journal of pathology\| PubMed ID: 33999421	2021
A computational method for prioritizing targeted therapies in precision oncology: performance analysis in the SHIVA01 trial. NPJ precision oncology\| PubMed ID: 34162980	2021
Human papilloma virus integration sites and genomic signatures in head and neck squamous cell carcinoma. Molecular oncology\| PubMed ID: 35398964	2022
Inversion of a topological domain leads to restricted changes in its gene expression and affects interdomain communication. Development (Cambridge, England)\| PubMed ID: 35502750	2022
Bioinformatics Methods for ChIP-seq Histone Analysis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 35733020	2022
Compartment-specific and ELAVL1-coordinated regulation of intronic polyadenylation isoforms by doxorubicin. Genome research\| PubMed ID: 35858751	2022
Genomics to select treatment for patients with metastatic breast cancer. Nature\| PubMed ID: 36071165	2022