Scott J. Snipas

NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute

Affiliated withSanford Burnham Prebys Medical Discovery Institute

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2022

Other Publications

Article	Year
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature\| PubMed ID: 26375259	2015
Counter Selection Substrate Library Strategy for Developing Specific Protease Substrates and Probes. Cell chemical biology\| PubMed ID: 27478158	2016
Highly sensitive and adaptable fluorescence-quenched pair discloses the substrate specificity profiles in diverse protease families. Scientific reports\| PubMed ID: 28230157	2017
SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth. The Journal of clinical investigation\| PubMed ID: 29227283	2018
Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1. The Journal of biological chemistry\| PubMed ID: 29414788	2018
Caspase selective reagents for diagnosing apoptotic mechanisms. Cell death and differentiation\| PubMed ID: 29748600	2019
Selective Substrates and Activity-Based Probes for Imaging of the Human Constitutive 20S Proteasome in Cells and Blood Samples. Journal of medicinal chemistry\| PubMed ID: 29806773	2018
Determination of extended substrate specificity of the MALT1 as a strategy for the design of potent substrates and activity-based probes. Scientific reports\| PubMed ID: 30375474	2018
Potent and selective caspase-2 inhibitor prevents MDM-2 cleavage in reversine-treated colon cancer cells. Cell death and differentiation\| PubMed ID: 30976094	2019
Exploring the prime site in caspases as a novel chemical strategy for understanding the mechanisms of cell death: a proof of concept study on necroptosis in cancer cells. Cell death and differentiation\| PubMed ID: 31209360	2020
Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation. Cell reports\| PubMed ID: 31216481	2019
Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through lipopolysaccharide. Nature microbiology\| PubMed ID: 31873204	2020
Detection of Active Granzyme A in NK92 Cells with Fluorescent Activity-Based Probe. Journal of medicinal chemistry\| PubMed ID: 32142286	2020
Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32345717	2020
Noninvasive optical detection of granzyme B from natural killer cells with enzyme-activated fluorogenic probes. The Journal of biological chemistry\| PubMed ID: 32439802	2020
Extended subsite profiling of the pyroptosis effector protein gasdermin D reveals a region recognized by inflammatory caspase-11. The Journal of biological chemistry\| PubMed ID: 32554464	2020
Engineering caspase 7 as an affinity reagent to capture proteolytic products. The FEBS journal\| PubMed ID: 32619291	2021
Multiplexed Probing of Proteolytic Enzymes Using Mass Cytometry-Compatible Activity-Based Probes. Journal of the American Chemical Society\| PubMed ID: 32870676	2020
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes. Chemical science\| PubMed ID: 32953009	2020
Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design. Science advances\| PubMed ID: 33067239	2020
NETosis occurs independently of neutrophil serine proteases. The Journal of biological chemistry\| PubMed ID: 33454002	2020
Evaluation of the effects of phosphorylation of synthetic peptide substrates on their cleavage by caspase-3 and -7. The Biochemical journal\| PubMed ID: 34037204	2021
Resurrection of an ancient inflammatory locus reveals switch to caspase-1 specificity on a caspase-4 scaffold. The Journal of biological chemistry\| PubMed ID: 35427646	2022
Gain of function of a metalloproteinase associated with multiple myeloma, bicuspid aortic valve, and Von Hippel-Lindau syndrome. The Biochemical journal\| PubMed ID: 35789254	2022