Sharon R. Lewin

Department of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity

Affiliated withThe University of Melbourne at the Peter Doherty Institute for Infection and Immunity Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity Alfred Hospital and Monash University

Research Area

Bioengineering

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2022

Other Publications

Article	Year
HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days--Implications for HIV Remission. PLoS pathogens\| PubMed ID: 26133551	2015
HealthMap: a cluster randomised trial of interactive health plans and self-management support to prevent coronary heart disease in people with HIV. BMC infectious diseases\| PubMed ID: 26945746	2016
No adverse safety or virological changes 2 years following vorinostat in HIV-infected individuals on antiretroviral therapy. AIDS (London, England)\| PubMed ID: 28301423	2017
Editorial: HIV and lipopolysaccharide: double trouble in the liver. Journal of leukocyte biology\| PubMed ID: 28468986	2017
Modeling of Antilatency Treatment in HIV: What Is the Optimal Duration of Antiretroviral Therapy-Free HIV Remission? Journal of virology\| PubMed ID: 29021399	2017
Getting the "Kill" into "Shock and Kill": Strategies to Eliminate Latent HIV. Cell host & microbe\| PubMed ID: 29324227	2018
The effect of antiretroviral intensification with dolutegravir on residual virus replication in HIV-infected individuals: a randomised, placebo-controlled, double-blind trial. The lancet. HIV\| PubMed ID: 29643011	2018
The Pathway To Establishing HIV Latency Is Critical to How Latency Is Maintained and Reversed. Journal of virology\| PubMed ID: 29643247	2018
Barriers and strategies to achieve a cure for HIV. The lancet. HIV\| PubMed ID: 29893245	2018
Strategies for an HIV cure: progress and challenges. Nature immunology\| PubMed ID: 30333614	2018
Functional cure of HIV: the scale of the challenge. Nature reviews. Immunology\| PubMed ID: 30410126	2019
Between a shock and a hard place: challenges and developments in HIV latency reversal. Current opinion in virology\| PubMed ID: 31048093	2019
CD4 T cell signatures in HIV infection. Nature immunology\| PubMed ID: 31308542	2019
Tesamorelin, liver fat, and NAFLD in the setting of HIV. The lancet. HIV\| PubMed ID: 31611037	2019
CXCR4-Using HIV Strains Predominate in Naive and Central Memory CD4 T Cells in People Living with HIV on Antiretroviral Therapy: Implications for How Latency Is Established and Maintained. Journal of virology\| PubMed ID: 31852784	2020
Limitations of dual-fluorescent HIV reporter viruses in a model of pre-activation latency. Journal of the International AIDS Society\| PubMed ID: 31855322	2019
Combination Immune Checkpoint Blockade to Reverse HIV Latency. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 31988180	2020
Kick and kill for HIV latency. Lancet (London, England)\| PubMed ID: 32085822	2020
A cure for HIV: how would we know? The lancet. HIV\| PubMed ID: 32169159	2020
Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19. Nature medicine\| PubMed ID: 32284614	2020
Evaluation of Serological Tests for SARS-CoV-2: Implications for Serology Testing in a Low-Prevalence Setting. The Journal of infectious diseases\| PubMed ID: 32761124	2020
Leveraging the advances in HIV for COVID-19. Lancet (London, England)\| PubMed ID: 33010825	2020
Multi-stakeholder consensus on a target product profile for an HIV cure. The lancet. HIV\| PubMed ID: 33271125	2021
Multiply spliced HIV RNA is a predictive measure of virus production ex vivo and in vivo following reversal of HIV latency. EBioMedicine\| PubMed ID: 33647768	2021
The impact of immune checkpoint therapy on the latent reservoir in HIV-infected individuals with cancer on antiretroviral therapy. AIDS (London, England)\| PubMed ID: 33859108	2021
Multi-site assessment of rapid, point-of-care antigen testing for the diagnosis of SARS-CoV-2 infection in a low-prevalence setting: A validation and implementation study. The Lancet regional health. Western Pacific\| PubMed ID: 33937887	2021
The RNA-Binding Proteins SRP14 and HMGB3 Control HIV-1 Tat mRNA Processing and Translation During HIV-1 Latency. Frontiers in genetics\| PubMed ID: 34194479	2021
Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance. Nature communications\| PubMed ID: 34257311	2021
Consensus statement on the role of health systems in advancing the long-term well-being of people living with HIV. Nature communications\| PubMed ID: 34272399	2021
Cell-Associated Human Immunodeficiency Virus (HIV) Ribonucleic Acid Has a Circadian Cycle in Males With HIV on Antiretroviral Therapy. The Journal of infectious diseases\| PubMed ID: 34655216	2022
Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021. Nature medicine\| PubMed ID: 34848888	2021
Combination Immune Checkpoint Blockade Enhances IL-2 and CD107a Production from HIV-Specific T Cells Ex Vivo in People Living with HIV on Antiretroviral Therapy. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 34853078	2022
Immune checkpoint blockade in HIV. EBioMedicine\| PubMed ID: 35123267	2022
Nanoscale probing and imaging of HIV-1 RNA in cells with a chimeric LNA-DNA sensor. Nanoscale\| PubMed ID: 35142755	2022
Antiretroviral initiation at ≥800 CD4+ cells/ mm 3 associated with lower HIV reservoir size. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 35396591	2022
Detection of Chimeric Cellular: HIV mRNAs Generated Through Aberrant Splicing in HIV-1 Latently Infected Resting CD4+ T Cells. Frontiers in cellular and infection microbiology\| PubMed ID: 35573784	2022
Factors associated with weak positive SARS-CoV-2 diagnosis by reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR). Pathology\| PubMed ID: 35778288	2022
Intact HIV Proviruses Persist in the Brain Despite Viral Suppression with ART. Annals of neurology\| PubMed ID: 35867351	2022
The role of latency reversal in HIV cure strategies. Journal of medical primatology\| PubMed ID: 36029233	2022
Nafamostat Mesylate for Treatment of COVID-19 in Hospitalised Patients: A Structured, Narrative Review. Clinical pharmacokinetics\| PubMed ID: 36040613	2022