Bostjan Humar

Swiss HPB Laboratory, University Hospital Zurich (USZ)

Affiliated withUniversity Hospital Zurich (USZ)University Hospital Zürich

Research Area

Medicine

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2022
Publication title	2023

Other Publications

Article	Year
"A randomized, double-blind study of the effects of omega-3 fatty acids (Omegaven) on outcome after major liver resection". BMC gastroenterology\| PubMed ID: 26268565	2015
Constitutive androstane receptor (Car)-driven regeneration protects liver from failure following tissue loss. Journal of hepatology\| PubMed ID: 26948495	2016
JNK1 induces hedgehog signaling from stellate cells to accelerate liver regeneration in mice. Journal of hepatology\| PubMed ID: 29709677	2018
Phase Ib dose-escalation study of the hypoxia-modifier Myo-inositol trispyrophosphate in patients with hepatopancreatobiliary tumors. Nature communications\| PubMed ID: 34155211	2021
Serotonin protects mouse liver from cholestatic injury by decreasing bile salt pool after bile duct ligation. Hepatology (Baltimore, Md.)\| PubMed ID: 22290718	2012
Liver failure after extended hepatectomy in mice is mediated by a p21-dependent barrier to liver regeneration. Gastroenterology\| PubMed ID: 22960658	2012
New insight into hyperthermic intraperitoneal chemotherapy: induction of oxidative stress dramatically enhanced tumor killing in in vitro and in vivo models. Annals of surgery\| PubMed ID: 23095616	2012
Systemic protection through remote ischemic preconditioning is spread by platelet-dependent signaling in mice. Hepatology (Baltimore, Md.)\| PubMed ID: 24700614	2014
Fasting protects liver from ischemic injury through Sirt1-mediated downregulation of circulating HMGB1 in mice. Journal of hepatology\| PubMed ID: 24751831	2014
ALPPS: from human to mice highlighting accelerated and novel mechanisms of liver regeneration. Annals of surgery\| PubMed ID: 25379855	2014
Hepatocellular carcinoma and lifestyles. Journal of hepatology\| PubMed ID: 26341826	2016
Selective portal vein injection for the design of syngeneic models of liver malignancy. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 26893160	2016
Stress-activated in hepatocytes promotes lipid and glucose metabolic disorders associated with high-fat diet consumption. Gut\| PubMed ID: 27222533	2016
Antihypoxic Potentiation of Standard Therapy for Experimental Colorectal Liver Metastasis through Myo-Inositol Trispyrophosphate. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 27489288	2016
Omega-3 Fatty Acids Protect Fatty and Lean Mouse Livers After Major Hepatectomy. Annals of surgery\| PubMed ID: 27564680	2017
Remote Ischemic Preconditioning: A Novel Strategy in Rescuing Older Livers From Ischemia-reperfusion Injury in a Rodent Model. Annals of surgery\| PubMed ID: 27584570	2016
Hypoxia-driven Hif2a coordinates mouse liver regeneration by coupling parenchymal growth to vascular expansion. Hepatology (Baltimore, Md.)\| PubMed ID: 27628483	2016
Development of OXY111A, a novel hypoxia-modifier as a potential antitumor agent in patients with hepato-pancreato-biliary neoplasms - Protocol of a first Ib/IIa clinical trial. BMC cancer\| PubMed ID: 27756258	2016
Hedgehog pathway mediates early acceleration of liver regeneration induced by a novel two-staged hepatectomy in mice. Journal of hepatology\| PubMed ID: 27771454	2017
PTEN Down-Regulation Promotes β-Oxidation to Fuel Hypertrophic Liver Growth After Hepatectomy in Mice. Hepatology (Baltimore, Md.)\| PubMed ID: 28437835	2017
The Allosteric Hemoglobin Effector ITPP Inhibits Metastatic Colon Cancer in Mice. Annals of surgery\| PubMed ID: 28742687	2017
Exogenous melatonin protects small-for-size liver grafts by promoting monocyte infiltration and releases interleukin-6. Journal of pineal research\| PubMed ID: 29505662	2018
Anti-tumoral effects of exercise on hepatocellular carcinoma growth. Hepatology communications\| PubMed ID: 29761175	2018
Novel Benefits of Remote Ischemic Preconditioning Through VEGF-dependent Protection From Resection-induced Liver Failure in the Mouse. Annals of surgery\| PubMed ID: 30080721	2018
Yes-associated protein promotes early hepatocyte cell cycle progression in regenerating liver after tissue loss. FASEB bioAdvances\| PubMed ID: 30740593	2019
Exploration of the Transcriptional Landscape of ALPPS Reveals the Pathways of Accelerated Liver Regeneration. Frontiers in oncology\| PubMed ID: 31824837	2019
S100A11/ANXA2 belongs to a tumour suppressor/oncogene network deregulated early with steatosis and involved in inflammation and hepatocellular carcinoma development. Gut\| PubMed ID: 31919231	2020
Large-Scale Profiling of Signaling Pathways Reveals a Distinct Demarcation between Normal and Extended Liver Resection. Cells\| PubMed ID: 32392745	2020
Exercise Attenuates the Transition from Fatty Liver to Steatohepatitis and Reduces Tumor Formation in Mice. Cancers\| PubMed ID: 32486073	2020
Hereditary diffuse gastric cancer: updated clinical practice guidelines. The Lancet. Oncology\| PubMed ID: 32758476	2020
Mir-21 Suppression Promotes Mouse Hepatocarcinogenesis. Cancers\| PubMed ID: 34638467	2021
Normalization of lipid oxidation defects arising from hypoxia early posthepatectomy prevents liver failure in mouse. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 36804129	2023