Marcelo D. Carattino

Renal-Electrolyte Division, University of Pittsburgh

Affiliated withUniversity of Pittsburgh University of Pittsburgh School of Medicine

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 2	2022
Publication title	2022
Publication title Cited by 14	2023

Other Publications

Article	Year
Syntaxin 1A regulates ENaC via domain-specific interactions. The Journal of biological chemistry\| PubMed ID: 12562778	2003
Arachidonic acid regulates surface expression of epithelial sodium channels. The Journal of biological chemistry\| PubMed ID: 12837767	2003
Maturation of the epithelial Na+ channel involves proteolytic processing of the alpha- and gamma-subunits. The Journal of biological chemistry\| PubMed ID: 12871941	2003
Epithelial Na+ channels are activated by laminar shear stress. The Journal of biological chemistry\| PubMed ID: 14625286	2004
Epithelial sodium channels are activated by furin-dependent proteolysis. The Journal of biological chemistry\| PubMed ID: 15007080	2004
Mutations in the pore region modify epithelial sodium channel gating by shear stress. The Journal of biological chemistry\| PubMed ID: 15569663	2005
Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells. The Journal of biological chemistry\| PubMed ID: 15753079	2005
The epithelial Na+ channel is inhibited by a peptide derived from proteolytic processing of its alpha subunit. The Journal of biological chemistry\| PubMed ID: 16690613	2006
Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit. The Journal of biological chemistry\| PubMed ID: 17199078	2007
Lack of a role of membrane-protein interactions in flow-dependent activation of ENaC. American journal of physiology. Renal physiology\| PubMed ID: 17459954	2007
Role of proteolysis in the activation of epithelial sodium channels. Current opinion in nephrology and hypertension\| PubMed ID: 17693760	2007
Defining an inhibitory domain in the alpha-subunit of the epithelial sodium channel. American journal of physiology. Renal physiology\| PubMed ID: 18032549	2008
Effect of aldosterone on BK channel expression in mammalian cortical collecting duct. American journal of physiology. Renal physiology\| PubMed ID: 18579708	2008
Proteolytic processing of the epithelial sodium channel gamma subunit has a dominant role in channel activation. The Journal of biological chemistry\| PubMed ID: 18650438	2008
Novel determinants of epithelial sodium channel gating within extracellular thumb domains. The Journal of biological chemistry\| PubMed ID: 19158091	2009
ENaC at the cutting edge: regulation of epithelial sodium channels by proteases. The Journal of biological chemistry\| PubMed ID: 19401469	2009
Conformational changes associated with proton-dependent gating of ASIC1a. The Journal of biological chemistry\| PubMed ID: 19858190	2009
Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel. American journal of physiology. Renal physiology\| PubMed ID: 20630937	2010
Clues to renal sodium retention. American journal of physiology. Renal physiology\| PubMed ID: 21228112	2011
Second transmembrane domain modulates epithelial sodium channel gating in response to shear stress. American journal of physiology. Renal physiology\| PubMed ID: 21307123	2011
Base of the thumb domain modulates epithelial sodium channel gating. The Journal of biological chemistry\| PubMed ID: 21367859	2011
Insights into the mechanism of pore opening of acid-sensing ion channel 1a. The Journal of biological chemistry\| PubMed ID: 21388961	2011
Structural mechanisms underlying the function of epithelial sodium channel/acid-sensing ion channel. Current opinion in nephrology and hypertension\| PubMed ID: 21709553	2011
TMPRSS4-dependent activation of the epithelial sodium channel requires cleavage of the γ-subunit distal to the furin cleavage site. American journal of physiology. Renal physiology\| PubMed ID: 21993886	2012
Contribution of residues in second transmembrane domain of ASIC1a protein to ion selectivity. The Journal of biological chemistry\| PubMed ID: 22371494	2012
Inhibitory tract traps the epithelial Na+ channel in a low activity conformation. The Journal of biological chemistry\| PubMed ID: 22511777	2012
Cation transport goes with the flow. American journal of physiology. Renal physiology\| PubMed ID: 22739535	2012
Role of the wrist domain in the response of the epithelial sodium channel to external stimuli. The Journal of biological chemistry\| PubMed ID: 23144453	2012
Gating transitions in the palm domain of ASIC1a. The Journal of biological chemistry\| PubMed ID: 23300086	2013
ENaC regulation by proteases and shear stress. Current molecular pharmacology\| PubMed ID: 23547932	2013
Bladder filling and voiding affect umbrella cell tight junction organization and function. American journal of physiology. Renal physiology\| PubMed ID: 23884145	2013
Regulation of large-conductance Ca2+-activated K+ channels by WNK4 kinase. American journal of physiology. Cell physiology\| PubMed ID: 23885063	2013
Independent contribution of extracellular proton binding sites to ASIC1a activation. The Journal of biological chemistry\| PubMed ID: 24142696	2013
Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24912170	2014
Prostasin interacts with the epithelial Na+ channel and facilitates cleavage of the γ-subunit by a second protease. American journal of physiology. Renal physiology\| PubMed ID: 25209858	2014
Intracellular Na+ regulates epithelial Na+ channel maturation. The Journal of biological chemistry\| PubMed ID: 25767115	2015
Increased urothelial paracellular transport promotes cystitis. American journal of physiology. Renal physiology\| PubMed ID: 26423859	2015
Cell-specific regulation of L-WNK1 by dietary K. American journal of physiology. Renal physiology\| PubMed ID: 26662201	2016
The Thumb Domain Mediates Acid-sensing Ion Channel Desensitization. The Journal of biological chemistry\| PubMed ID: 27015804	2016
Specific Palmitoyltransferases Associate with and Activate the Epithelial Sodium Channel. The Journal of biological chemistry\| PubMed ID: 28154191	2017
Urothelial Tight Junction Barrier Dysfunction Sensitizes Bladder Afferents. eNeuro\| PubMed ID: 28560313	2017
Expression and Analysis of Flow-regulated Ion Channels in Oocytes. Bio-protocol\| PubMed ID: 28670605	2017
Cdc42 activation couples fluid shear stress to apical endocytosis in proximal tubule cells. Physiological reports\| PubMed ID: 29038362	2017
ASIC3 fine-tunes bladder sensory signaling. American journal of physiology. Renal physiology\| PubMed ID: 29561183	2018
Molecular basis of inhibition of acid sensing ion channel 1A by diminazene. PloS one\| PubMed ID: 29782492	2018
Urinary K promotes irritative voiding symptoms and pain in the face of urothelial barrier dysfunction. Scientific reports\| PubMed ID: 30940909	2019
Renal sensory nerves increase sympathetic nerve activity and blood pressure in 2-kidney 1-clip hypertensive mice. Journal of neurophysiology\| PubMed ID: 31091159	2019
Murine epithelial sodium (Na) channel regulation by biliary factors. The Journal of biological chemistry\| PubMed ID: 31092599	2019
Expression and distribution of PIEZO1 in the mouse urinary tract. American journal of physiology. Renal physiology\| PubMed ID: 31166705	2019
Molecular determinants of afferent sensitization in a rat model of cystitis with urothelial barrier dysfunction. Journal of neurophysiology\| PubMed ID: 31314637	2019
Acid-sensing ion channels in sensory signaling. American journal of physiology. Renal physiology\| PubMed ID: 31984789	2020
Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel. The Journal of biological chemistry\| PubMed ID: 32079677	2020
The Urothelium: Life in a Liquid Environment. Physiological reviews\| PubMed ID: 32191559	2020
Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception. JCI insight\| PubMed ID: 34464353	2021
Acid-sensing ion channels modulate bladder nociception. American journal of physiology. Renal physiology\| PubMed ID: 34514879	2021
Bladder infection with uropathogenic increases the excitability of afferent neurons. American journal of physiology. Renal physiology\| PubMed ID: 34779263	2022
Studies of ultrastructure, gene expression, and marker analysis reveal that mouse bladder PDGFRA interstitial cells are fibroblasts. American journal of physiology. Renal physiology\| PubMed ID: 35834272	2022
Functional characterization of ion channels expressed in kidney organoids derived from human induced pluripotent stem cells. American journal of physiology. Renal physiology\| PubMed ID: 35979965	2022