Qun Lu

Department of Anatomy and Cell Biology, East Carolina University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2022

Other Publications

Article	Year
14-3-3É›/Î¶ Affects the stability of Î´-catenin and regulates Î´-catenin-induced dendrogenesis. FEBS open bio\| PubMed ID: 23772369	2013
Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells. Molecular biology of the cell\| PubMed ID: 11950934	2002
Dendrite-like process formation and cytoskeletal remodeling regulated by delta-catenin expression. Experimental cell research\| PubMed ID: 11969288	2002
Association of nonreceptor tyrosine kinase c-yes with tight junction protein occludin by coimmunoprecipitation assay. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 12616717	2003
Abl tyrosine kinase promotes dendrogenesis by inducing actin cytoskeletal rearrangements in cooperation with Rho family small GTPases in hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15456825	2004
Overexpression of claudin-7 decreases the paracellular Cl- conductance and increases the paracellular Na+ conductance in LLC-PK1 cells. Journal of cell science\| PubMed ID: 15928046	2005
Increased expression of delta-catenin/neural plakophilin-related armadillo protein is associated with the down-regulation and redistribution of E-cadherin and p120ctn in human prostate cance... Human pathology\| PubMed ID: 16226102	2005
Presenilin-1 inhibits delta-catenin-induced cellular branching and promotes delta-catenin processing and turnover. Biochemical and biophysical research communications\| PubMed ID: 17097608	2006
WNK4 phosphorylates ser(206) of claudin-7 and promotes paracellular Cl(-) permeability. FEBS letters\| PubMed ID: 17651736	2007
Delta-catenin-induced dendritic morphogenesis. An essential role of p190RhoGEF interaction through Akt1-mediated phosphorylation. The Journal of biological chemistry\| PubMed ID: 17993462	2008
Identification of E2F1 as a positive transcriptional regulator for delta-catenin. Biochemical and biophysical research communications\| PubMed ID: 18302937	2008
Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants. Neurotoxicology\| PubMed ID: 18539332	2008
E-Cadherin negatively modulates delta-catenin-induced morphological changes and RhoA activity reduction by competing with p190RhoGEF for delta-catenin. Biochemical and biophysical research communications\| PubMed ID: 18930028	2008
Increased nucleotide polymorphic changes in the 5'-untranslated region of delta-catenin (CTNND2) gene in prostate cancer. Oncogene\| PubMed ID: 18978817	2009
Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairment. PloS one\| PubMed ID: 18978948	2008
Identification of extracellular delta-catenin accumulation for prostate cancer detection. The Prostate\| PubMed ID: 19116988	2009
Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains. Molecular neurodegeneration\| PubMed ID: 19243613	2009
delta-Catenin promotes prostate cancer cell growth and progression by altering cell cycle and survival gene profiles. Molecular cancer\| PubMed ID: 19284555	2009
Methodology to obtain a mixed sural nerve recording in mice. American journal of physical medicine & rehabilitation / Association of Academic Physiatrists\| PubMed ID: 19325459	2009
Signaling through Rho GTPase pathway as viable drug target. Current medicinal chemistry\| PubMed ID: 19355891	2009
Analysis of claudin genes in pediatric patients with Bartter's syndrome. Annals of the New York Academy of Sciences\| PubMed ID: 19538297	2009
GSK-3 phosphorylates delta-catenin and negatively regulates its stability via ubiquitination/proteosome-mediated proteolysis. The Journal of biological chemistry\| PubMed ID: 19706605	2009
Renal salt wasting and chronic dehydration in claudin-7-deficient mice. American journal of physiology. Renal physiology\| PubMed ID: 19759267	2010
Xenopus delta-catenin is essential in early embryogenesis and is functionally linked to cadherins and small GTPases. Journal of cell science\| PubMed ID: 19843587	2009
Rho kinase inhibitor Y-27632 facilitates recovery from experimental peripheral neuropathy induced by anti-cancer drug cisplatin. Neurotoxicology\| PubMed ID: 20060419	2010
Isoform- and dose-sensitive feedback interactions between paired box 6 gene and delta-catenin in cell differentiation and death. Experimental cell research\| PubMed ID: 20074565	2010
Delta-catenin affects the localization and stability of p120-catenin by competitively interacting with E-cadherin. Molecules and cells\| PubMed ID: 20108168	2010
Pro-oncogenic and anti-oncogenic pathways: opportunities and challenges of cancer therapy. Future oncology (London, England)\| PubMed ID: 20373871	2010
Delta-catenin/NPRAP: A new member of the glycogen synthase kinase-3beta signaling complex that promotes beta-catenin turnover in neurons. Journal of neuroscience research\| PubMed ID: 20623542	2010
δ-Catenin dysregulation in cancer: interactions with E-cadherin and beyond. The Journal of pathology\| PubMed ID: 20715154	2010
Alzheimer's disease-linked presenilin mutation (PS1M146L) induces filamin expression and γ-secretase independent redistribution. Journal of Alzheimer's disease : JAD\| PubMed ID: 20847418	2010
Human homolog of Drosophila Hairy and enhancer of split 1, Hes1, negatively regulates δ-catenin (CTNND2) expression in cooperation with E2F1 in prostate cancer. Molecular cancer\| PubMed ID: 21106062	2010
Fe3O4 nanoparticles with daunorubicin induce apoptosis through caspase 8-PARP pathway and inhibit K562 leukemia cell-induced tumor growth in vivo. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 21333751	2011
Hydroxycamptothecin-loaded Fe3O4 nanoparticles induce human lung cancer cell apoptosis through caspase-8 pathway activation and disrupt tight junctions. Cancer science\| PubMed ID: 21435100	2011
Claudin-7 inhibits human lung cancer cell migration and invasion through ERK/MAPK signaling pathway. Experimental cell research\| PubMed ID: 21641901	2011
Inflammation and disruption of the mucosal architecture in claudin-7-deficient mice. Gastroenterology\| PubMed ID: 22044670	2012
Î´-Catenin promotes E-cadherin processing and activates Î²-catenin-mediated signaling: Implications on human prostate cancer progression. Biochimica et biophysica acta\| PubMed ID: 22261283	2012
Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23284167	2013
Claudin-7 increases chemosensitivity to cisplatin through the upregulation of caspase pathway in human NCI-H522 lung cancer cells. Cancer science\| PubMed ID: 23433123	2013
The claudin family of proteins in human malignancy: a clinical perspective. Cancer management and research\| PubMed ID: 24232410	2013
C-Src-mediated phosphorylation of δ-catenin increases its protein stability and the ability of inducing nuclear distribution of β-catenin. Biochimica et biophysica acta\| PubMed ID: 24412473	2014
Claudins in intestines: Distribution and functional significance in health and diseases. Tissue barriers\| PubMed ID: 24478939	2013
Cytotoxicity of cyclometalated platinum complexes based on tridentate NCN and CNN-coordinating ligands: remarkable coordination dependence. Journal of inorganic biochemistry\| PubMed ID: 24531534	2014
VASP activation via the Gα13/RhoA/PKA pathway mediates cucurbitacin-B-induced actin aggregation and cofilin-actin rod formation. PloS one\| PubMed ID: 24691407	2014
δ-Catenin, a Wnt/β-catenin modulator, reveals inducible mutagenesis promoting cancer cell survival adaptation and metabolic reprogramming. Oncogene\| PubMed ID: 24727894	2015
δ-Catenin as a potential cancer biomarker. Pathology international\| PubMed ID: 24888779	2014
Amelioration of cisplatin-induced experimental peripheral neuropathy by a small molecule targeting p75 NTR. Neurotoxicology\| PubMed ID: 25277379	2014
A non-tight junction function of claudin-7-Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment. Molecular cancer\| PubMed ID: 26081244	2015
Early alterations in blood and brain RANTES and MCP-1 expression and the effect of exercise frequency in the 3xTg-AD mouse model of Alzheimer's disease. Neuroscience letters\| PubMed ID: 26547034	2016
Genetic alterations of δ-catenin/NPRAP/Neurojungin (CTNND2): functional implications in complex human diseases. Human genetics\| PubMed ID: 27380241	2016
Cdc42 Signaling Pathway Inhibition as a Therapeutic Target in Ras- Related Cancers. Current medicinal chemistry\| PubMed ID: 28571533	2017
Rho GTPases as therapeutic targets in Alzheimer's disease. Alzheimer's research & therapy\| PubMed ID: 29246246	2017
Epithelial Mesenchymal Transition in Embryonic Development, Tissue Repair and Cancer: A Comprehensive Overview. Journal of clinical medicine\| PubMed ID: 29271928	2017
The effects of exercise on hypothalamic neurodegeneration of Alzheimer's disease mouse model. PloS one\| PubMed ID: 29293568	2018
Inhibition of Cdc42-intersectin interaction by small molecule ZCL367 impedes cancer cell cycle progression, proliferation, migration, and tumor growth. Cancer biology & therapy\| PubMed ID: 30849276	2019
Claudin-7 modulates cell-matrix adhesion that controls cell migration, invasion and attachment of human HCC827 lung cancer cells. Oncology letters\| PubMed ID: 30854065	2019
Therapeutic Effect of Y-27632 on Tumorigenesis and Cisplatin-Induced Peripheral Sensory Loss through RhoA-NF-κB. Molecular cancer research : MCR\| PubMed ID: 31189689	2019
Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and Differentiation. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 31874254	2020
Intratumor δ-catenin heterogeneity driven by genomic rearrangement dictates growth factor dependent prostate cancer progression. Oncogene\| PubMed ID: 32313227	2020
Selective axonal translation of the mRNA isoform encoding prenylated Cdc42 supports axon growth. Journal of cell science\| PubMed ID: 33674450	2021
Pharmacological Modulators of Small GTPases of Rho Family in Neurodegenerative Diseases. Frontiers in cellular neuroscience\| PubMed ID: 34054432	2021
The effect of exercise on early sensorimotor performance alterations in the 3xTg-AD model of Alzheimer's disease. Neuroscience research\| PubMed ID: 35033583	2022
TRPV4: En RhoA To a Cure? BioEssays : news and reviews in molecular, cellular and developmental biology\| PubMed ID: 35441721	2022
Nanoarchitecture and molecular interactions of epithelial cell junction proteins revealed by super-resolution microscopy. Annals of the New York Academy of Sciences\| PubMed ID: 35819053	2022