Eiji Shigetomi

Departments of Physiology and Neurobiology, David Geffen School of Medicine, University of California, Los Angeles

Affiliated withDavid Geffen School of Medicine, University of California, Los Angeles University of Yamanashi

Research Area

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 16	2009
Publication title Cited by 9	2022
Publication title Cited by 3	2022

Other Publications

Article	Year
Analysis of the molecular mechanisms controlling synaptic transmission by patch-clamp recording in brainstem slices. Nihon yakurigaku zasshi. Folia pharmacologica Japonica\| PubMed ID: 12777844	2003
Differential increases in P2X receptor levels in rat vagal efferent neurones following a vagal nerve section. Brain research\| PubMed ID: 12788520	2003
ATP- and adenosine-mediated signaling in the central nervous system: synaptic purinoceptors: the stage for ATP to play its "dual-role". Journal of pharmacological sciences\| PubMed ID: 14978346	2004
Action potential-independent release of glutamate by Ca2+ entry through presynaptic P2X receptors elicits postsynaptic firing in the brainstem autonomic network. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15044552	2004
A dual-role played by extracellular ATP in frequency-filtering of the nucleus Tractus solitarii network. Advances in experimental medicine and biology\| PubMed ID: 15602957	2004
Blocker-resistant presynaptic voltage-dependent Ca2+ channels underlying glutamate release in mice nucleus tractus solitarii. Brain research\| PubMed ID: 16814754	2006
Facilitation of spontaneous glycine release by anoxia potentiates NMDA receptor current in the hypoglossal motor neurons of the rat. The European journal of neuroscience\| PubMed ID: 17408431	2007
[Purinergic regulatory complex in the brain synapses]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology\| PubMed ID: 17633523	2007
Tracking transmitter-gated P2X cation channel activation in vitro and in vivo. Nature methods\| PubMed ID: 18084300	2008
Two forms of astrocyte calcium excitability have distinct effects on NMDA receptor-mediated slow inward currents in pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18579739	2008
A genetically targeted optical sensor to monitor calcium signals in astrocyte processes. Nature neuroscience\| PubMed ID: 20495558	2010
Monitoring astrocyte calcium microdomains with improved membrane targeted GCaMP reporters. Neuron glia biology\| PubMed ID: 21205365	2010
Bulk loading of calcium indicator dyes to study astrocyte physiology: key limitations and improvements using morphological maps. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21697385	2011
[Synaptic regulation by astrocytes]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica\| PubMed ID: 21986065	2011
Neuronal P2X2 receptors are mobile ATP sensors that explore the plasma membrane when activated. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22090499	2011
TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3. Nature neuroscience\| PubMed ID: 22158513	2012
Imaging calcium microdomains within entire astrocyte territories and endfeet with GCaMPs expressed using adeno-associated viruses. The Journal of general physiology\| PubMed ID: 23589582	2013
Müller cell-mediated neurite outgrowth of the retinal ganglion cells via P2Y receptor signals. Journal of neurochemistry\| PubMed ID: 26560804	2016
Probing the Complexities of Astrocyte Calcium Signaling. Trends in cell biology\| PubMed ID: 26896246	2016
Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain. The Journal of clinical investigation\| PubMed ID: 27064281	2016
The Clock mutant mouse is a novel experimental model for nocturia and nocturnal polyuria. Neurourology and urodynamics\| PubMed ID: 27348079	2017
Urothelial ATP exocytosis: regulation of bladder compliance in the urine storage phase. Scientific reports\| PubMed ID: 27412485	2016
Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa. PloS one\| PubMed ID: 28060940	2017
P2Y-deficiency increases micturition frequency and attenuates sustained contractility of the urinary bladder in mice. Scientific reports\| PubMed ID: 28396595	2017
Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y Receptor Downregulation. Cell reports\| PubMed ID: 28494865	2017
Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway. Nature communications\| PubMed ID: 28642575	2017
Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence. Neuron\| PubMed ID: 28712653	2017
The Circadian expression of Piezo1, TRPV4, Connexin26, and VNUT, associated with the expression levels of the clock genes in mouse primary cultured urothelial cells. Neurourology and urodynamics\| PubMed ID: 28881406	2018
Author Correction: Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway. Nature communications\| PubMed ID: 29138397	2017
Role of Purinergic Receptor P2Y1 in Spatiotemporal Ca Dynamics in Astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 29305530	2018
Aberrant astrocyte Ca signals "AxCa signals" exacerbate pathological alterations in an Alexander disease model. Glia\| PubMed ID: 29383757	2018
The oscillation of intracellular Ca influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium. Scientific reports\| PubMed ID: 29632308	2018
Anti-Depressant Fluoxetine Reveals its Therapeutic Effect Via Astrocytes. EBioMedicine\| PubMed ID: 29887330	2018
The time-dependent variation of ATP release in mouse primary-cultured urothelial cells is regulated by the clock gene. Neurourology and urodynamics\| PubMed ID: 30106187	2018
Aberrant Calcium Signals in Reactive Astrocytes: A Key Process in Neurological Disorders. International journal of molecular sciences\| PubMed ID: 30823575	2019
Intermittent restraint stress induces circadian misalignment in the mouse bladder, leading to nocturia. Scientific reports\| PubMed ID: 31296902	2019
Author Correction: Intermittent restraint stress induces circadian misalignment in the mouse bladder, leading to nocturia. Scientific reports\| PubMed ID: 31700120	2019
Reactive astrocyte-driven epileptogenesis is induced by microglia initially activated following status epilepticus. JCI insight\| PubMed ID: 33830944	2021
Different effects of GsMTx4 on nocturia associated with the circadian clock and Piezo1 expression in mice. Life sciences\| PubMed ID: 33930366	2021
Transnasal transplantation of human induced pluripotent stem cell-derived microglia to the brain of immunocompetent mice. Glia\| PubMed ID: 34309082	2021
Adenosine A receptor down-regulates metabotropic glutamate receptor 5 in astrocytes during postnatal development. Glia\| PubMed ID: 34339538	2021
Abnormal Ca Signals in Reactive Astrocytes as a Common Cause of Brain Diseases. International journal of molecular sciences\| PubMed ID: 35008573	2021
Effects of fatty acid metabolites on nocturia. Scientific reports\| PubMed ID: 35197540	2022
Transient astrocytic mGluR5 expression drives synaptic plasticity and subsequent chronic pain in mice. The Journal of experimental medicine\| PubMed ID: 35319723	2022