Yingfu Li

Department of Biochemistry and Biomedical Sciences, McMaster University

Affiliated withMcMaster University McMaster University

Research Area

Biography

Yingfu Li has not added Biography.
If you are Yingfu Li and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 17	2012
Publication title Cited by 5	2016

Other Publications

Article	Year
Sequence diversity, metal specificity, and catalytic proficiency of metal-dependent phosphorylating DNA enzymes. Chemistry & biology\| PubMed ID: 11983339	2002
Tripartite molecular beacons. Nucleic acids research\| PubMed ID: 12235396	2002
Making AppDNA using T4 DNA ligase. Bioorganic chemistry\| PubMed ID: 12485593	2002
An efficient RNA-cleaving DNA enzyme that synchronizes catalysis with fluorescence signaling. Journal of the American Chemical Society\| PubMed ID: 12517153	2003
Affinity analysis of a protein-aptamer complex using nonequilibrium capillary electrophoresis of equilibrium mixtures. Analytical chemistry\| PubMed ID: 12659199	2003
Structure-switching signaling aptamers. Journal of the American Chemical Society\| PubMed ID: 12696895	2003
Assemblage of signaling DNA enzymes with intriguing metal-ion specificities and pH dependences. Journal of the American Chemical Society\| PubMed ID: 12812493	2003
Ligating DNA with DNA. Journal of the American Chemical Society\| PubMed ID: 15025472	2004
Structure-switching signaling aptamers: transducing molecular recognition into fluorescence signaling. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 15079825	2004
Dinucleotide junction cleavage versatility of 8-17 deoxyribozyme. Chemistry & biology\| PubMed ID: 15112995	2004
Tracing sequence diversity change of RNA-cleaving deoxyribozymes under increasing selection pressure during in vitro selection. Biochemistry\| PubMed ID: 15274624	2004
Signaling aptamers for monitoring enzymatic activity and for inhibitor screening. Chembiochem : a European journal of chemical biology\| PubMed ID: 15300841	2004
Synthesis and characterization of topologically linked single-stranded DNA rings. Bioorganic chemistry\| PubMed ID: 15530998	2004
In vitro selection of structure-switching signaling aptamers. Angewandte Chemie (International ed. in English)\| PubMed ID: 15643624	2005
Benzimidazole derivatives as novel nonpeptide luteinizing hormone-releasing hormone (LHRH) antagonists. Part 1: Benzimidazole-5-sulfonamides. Bioorganic & medicinal chemistry letters\| PubMed ID: 15664860	2005
Benzimidazole derivatives as novel nonpeptide luteinizing hormone-releasing hormone (LHRH) antagonists. Part 2: Benzimidazole-5-sulfonamides. Bioorganic & medicinal chemistry letters\| PubMed ID: 15664861	2005
Tau protein binds single-stranded DNA sequence specifically--the proof obtained in vitro with non-equilibrium capillary electrophoresis of equilibrium mixtures. FEBS letters\| PubMed ID: 15733843	2005
Secondary-structure characterization of two proficient kinase deoxyribozymes. Biochemistry\| PubMed ID: 15751953	2005
Benzimidazoles as non-peptide luteinizing hormone-releasing hormone (LHRH) antagonists. Part 3: Discovery of 1-(1H-benzimidazol-5-yl)-3-tert-butylurea derivatives. Bioorganic & medicinal chemistry letters\| PubMed ID: 15837306	2005
Diverse evolutionary trajectories characterize a community of RNA-cleaving deoxyribozymes: a case study into the population dynamics of in vitro selection. Journal of molecular evolution\| PubMed ID: 16007486	2005
Entrapment of fluorescent signaling DNA aptamers in sol-gel-derived silica. Analytical chemistry\| PubMed ID: 16013839	2005
A DNA-protein nanoengine for "on-demand" release and precise delivery of molecules. Angewandte Chemie (International ed. in English)\| PubMed ID: 16041813	2005
Characterizing the secondary structure and identifying functionally essential nucleotides of pH6DZ1, a fluorescence-signaling and RNA-cleaving deoxyribozyme. Biochemistry\| PubMed ID: 16142904	2005
Aptamers with fluorescence-signaling properties. Methods (San Diego, Calif.)\| PubMed ID: 16199173	2005
Benzimidazole-5-sulfonamides as novel nonpeptide luteinizing hormone releasing hormone (LHRH) antagonists: minimization of mechanism-based CYP3A4 inhibition. Chemical & pharmaceutical bulletin\| PubMed ID: 16204990	2005
Characterization of a catalytically efficient acidic RNA-cleaving deoxyribozyme. Nucleic acids research\| PubMed ID: 16391005	2005
Quenching of fluorophore-labeled DNA oligonucleotides by divalent metal ions: implications for selection, design, and applications of signaling aptamers and signaling deoxyribozymes. Journal of the American Chemical Society\| PubMed ID: 16417367	2006
Revitalization of six abandoned catalytic DNA species reveals a common three-way junction framework and diverse catalytic cores. Journal of molecular biology\| PubMed ID: 16480741	2006
DNA polymerization on gold nanoparticles through rolling circle amplification: towards novel scaffolds for three-dimensional periodic nanoassemblies. Angewandte Chemie (International ed. in English)\| PubMed ID: 16526071	2006
Solid-phase enzyme activity assay utilizing an entrapped fluorescence-signaling DNA aptamer. Angewandte Chemie (International ed. in English)\| PubMed ID: 16619330	2006
Nucleic acid aptamers and enzymes as sensors. Current opinion in chemical biology\| PubMed ID: 16678470	2006
Characterization of long RNA-cleaving deoxyribozymes with short catalytic cores: the effect of excess sequence elements on the outcome of in vitro selection. Nucleic acids research\| PubMed ID: 16682452	2006
Phosphoester-transfer mechanism of an RNA-cleaving acidic deoxyribozyme revealed by radioactivity tracking and enzymatic digestion. Chemical communications (Cambridge, England)\| PubMed ID: 16733579	2006
Small-molecule screening made simple for a difficult target with a signaling nucleic acid aptamer that reports on deaminase activity. Angewandte Chemie (International ed. in English)\| PubMed ID: 16856187	2006
Catalysis and rational engineering of trans-acting pH6DZ1, an RNA-cleaving and fluorescence-signaling deoxyribozyme with a four-way junction structure. Chembiochem : a European journal of chemical biology\| PubMed ID: 16888734	2006
Long-period grating refractive index sensor with a modified cladding structure for large operational range and high sensitivity. Applied optics\| PubMed ID: 16892115	2006
Wrapping single-walled carbon nanotubes with long single-stranded DNA molecules produced by rolling circle amplification. Chemical communications (Cambridge, England)\| PubMed ID: 17047771	2006
Evolution of high-branching deoxyribozymes from a catalytic DNA with a three-way junction. Chemistry & biology\| PubMed ID: 17052610	2006
Characterization of a fluorescence-signaling and RNA-cleaving deoxyribozyme. Nucleic acids symposium series (2004)\| PubMed ID: 17150630	2005
Efficient signaling platforms built from a small catalytic DNA and doubly labeled fluorogenic substrates. Nucleic acids research\| PubMed ID: 17169997	2007
Adsorption and covalent coupling of ATP-binding DNA aptamers onto cellulose. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 17241049	2007
Multiple occurrences of an efficient self-phosphorylating deoxyribozyme motif. Biochemistry\| PubMed ID: 17263557	2007
A synthetic luxCDABE gene cluster optimized for expression in high-GC bacteria. Nucleic acids research\| PubMed ID: 17337439	2007
Entrapment of fluorescence signaling DNA enzymes in sol-gel-derived materials for metal ion sensing. Analytical chemistry\| PubMed ID: 17378543	2007
Simple and rapid colorimetric biosensors based on DNA aptamer and noncrosslinking gold nanoparticle aggregation. Chembiochem : a European journal of chemical biology\| PubMed ID: 17410623	2007
Aptamers and small molecules play tug of war. Chemistry & biology\| PubMed ID: 17656309	2007
Simple and rapid colorimetric enzyme sensing assays using non-crosslinking gold nanoparticle aggregation. Chemical communications (Cambridge, England)\| PubMed ID: 17851609	2007
Isolation of DNA aptamers for CDP-ribitol synthase, and characterization of their inhibitory and structural properties. Chembiochem : a European journal of chemical biology\| PubMed ID: 17929340	2007
Enzymatic manipulations of DNA oligonucleotides on microgel: towards development of DNA-microgel bioassays. Chemical communications (Cambridge, England)\| PubMed ID: 17971955	2007
Understanding DNA-based catalysis one molecule at a time. Nature chemical biology\| PubMed ID: 18007644	2007
Enzymatic incorporation of 2-amino-6-vinylpurine derivative. Nucleic acids symposium series (2004)\| PubMed ID: 18029734	2007
Simple fluorescent sensors engineered with catalytic DNA 'MgZ' based on a non-classic allosteric design. PloS one\| PubMed ID: 18030352	2007
A deoxyribozyme with a novel guanine quartet-helix pseudoknot structure. Journal of molecular biology\| PubMed ID: 18054790	2008
Sequence-function relationships provide new insight into the cleavage site selectivity of the 8-17 RNA-cleaving deoxyribozyme. Nucleic acids research\| PubMed ID: 18203744	2008
Microgel-based inks for paper-supported biosensing applications. Biomacromolecules\| PubMed ID: 18293902	2008
DNA aptamer folding on gold nanoparticles: from colloid chemistry to biosensors. Journal of the American Chemical Society\| PubMed ID: 18293985	2008
Chemical biology meets systems biology. Introduction. Biochemistry and cell biology = Biochimie et biologie cellulaire\| PubMed ID: 18509889	2008
Enzymatic cleavage of nucleic acids on gold nanoparticles: a generic platform for facile colorimetric biosensors. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 18537135	2008
A FACS-based approach to engineering artificial riboswitches. Chembiochem : a European journal of chemical biology\| PubMed ID: 18613182	2008
In vitro selection of small RNA-cleaving deoxyribozymes that cleave pyrimidine-pyrimidine junctions. Nucleic acids research\| PubMed ID: 18644842	2008
Rolling circle amplification: applications in nanotechnology and biodetection with functional nucleic acids. Angewandte Chemie (International ed. in English)\| PubMed ID: 18680110	2008
Investigation of DNA as a catalyst for Henry reaction in water. Chemical communications (Cambridge, England)\| PubMed ID: 18685779	2008
Design of gold nanoparticle-based colorimetric biosensing assays. Chembiochem : a European journal of chemical biology\| PubMed ID: 18821551	2008
Paper-based bioassays using gold nanoparticle colorimetric probes. Analytical chemistry\| PubMed ID: 18847216	2008
Periodic assembly of nanospecies on repetitive DNA sequences generated on gold nanoparticles by rolling circle amplification. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19031062	2008
DNAzyme-mediated catalysis with only guanosine and cytidine nucleotides. Nucleic acids research\| PubMed ID: 19050014	2009
Identification of a toxic peptide through bidirectional expression of small RNAs. Chembiochem : a European journal of chemical biology\| PubMed ID: 19090519	2009
In vitro selection of protein-binding DNA aptamers as ligands for biosensing applications. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19159108	2009
Incorporation of an inducible nucleotide analog into DNA by DNA polymerases. Bioorganic & medicinal chemistry\| PubMed ID: 19286386	2009
Biologically inspired synthetic enzymes made from DNA. Chemistry & biology\| PubMed ID: 19318212	2009
A genotype-to-phenotype map of in vitro selected RNA-cleaving DNAzymes: implications for accessing the target phenotype. Nucleic acids research\| PubMed ID: 19357090	2009
Colorimetric sensing by using allosteric-DNAzyme-coupled rolling circle amplification and a peptide nucleic acid-organic dye probe. Angewandte Chemie (International ed. in English)\| PubMed ID: 19360817	2009
Kinetics of signaling-DNA-aptamer-ATP binding. Physical review. E, Statistical, nonlinear, and soft matter physics\| PubMed ID: 19391970	2009
Characterization of an RNA-cleaving deoxyribozyme with optimal activity at pH 5. Biochemistry\| PubMed ID: 19583262	2009
Detection of DNA using bioactive paper strips. Chemical communications (Cambridge, England)\| PubMed ID: 19865676	2009
A versatile endoribonuclease mimic made of DNA: characteristics and applications of the 8-17 RNA-cleaving DNAzyme. Chembiochem : a European journal of chemical biology\| PubMed ID: 20213779	2010
A complex RNA-cleaving DNAzyme that can efficiently cleave a pyrimidine-pyrimidine junction. Journal of molecular biology\| PubMed ID: 20630470	2010
Using a riboswitch sensor to examine coenzyme B(12) metabolism and transport in E. coli. Chemistry & biology\| PubMed ID: 20659688	2010
Influence of cleavage site on global folding of an RNA-cleaving DNAzyme. Chembiochem : a European journal of chemical biology\| PubMed ID: 20665772	2010
Probing the function of nucleotides in the catalytic cores of the 8-17 and 10-23 DNAzymes by abasic nucleotide and C3 spacer substitutions. Biochemistry\| PubMed ID: 20698496	2010
A general approach to the construction of structure-switching reporters from RNA aptamers. Angewandte Chemie (International ed. in English)\| PubMed ID: 20845339	2010
The structural diversity of deoxyribozymes. Molecules (Basel, Switzerland)\| PubMed ID: 20877222	2010
Decoding toxicity: deducing the sequence requirements of IbsC, a type I toxin in Escherichia coli. The Journal of biological chemistry\| PubMed ID: 20980267	2010
Surface immobilization of structure-switching DNA aptamers on macroporous sol-gel-derived films for solid-phase biosensing applications. Analytical chemistry\| PubMed ID: 21214191	2011
Modulation of DNA-modified gold-nanoparticle stability in salt with concatemeric single-stranded DNAs for colorimetric bioassay development. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 21294175	2011
Fluorogenic DNAzyme probes as bacterial indicators. Angewandte Chemie (International ed. in English)\| PubMed ID: 21412961	2011
Characterization of non-8-17 sequences uncovers structurally diverse RNA-cleaving deoxyribozymes. Molecular bioSystems\| PubMed ID: 21523306	2011
Enhancing sensitivity and selectivity of long-period grating sensors using structure-switching aptamers bound to gold-doped macroporous silica coatings. Analytical chemistry\| PubMed ID: 21951178	2011
Advancements in using reporter DNAzymes for identifying pathogenic bacteria at speed and with convenience. Future microbiology\| PubMed ID: 21958136	2011
Developing fluorogenic RNA-cleaving DNAzymes for biosensing applications. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22315083	2012
Multiplexed paper test strip for quantitative bacterial detection. Analytical and bioanalytical chemistry\| PubMed ID: 22526653	2012
Stabilizing structure-switching signaling RNA aptamers by entrapment in sol-gel derived materials for solid-phase assays. Journal of the American Chemical Society\| PubMed ID: 22724553	2012
Lighting Up RNA-Cleaving DNAzymes for Biosensing. Journal of nucleic acids\| PubMed ID: 23209883	2012
Artificially created nucleic acids and peptides/proteins in chemical biology. Journal of nucleic acids\| PubMed ID: 23401748	2013
A highly efficient molecular cloning platform that utilises a small bacterial toxin gene. Chembiochem : a European journal of chemical biology\| PubMed ID: 23512843	2013
Quality control certification of RNA aptamer-based detection. Chembiochem : a European journal of chemical biology\| PubMed ID: 23592300	2013
Turning a kinase deoxyribozyme into a sensor. Journal of the American Chemical Society\| PubMed ID: 23611670	2013
A novel phosphorescence sensor for Co(2+) ion based on Mn-doped ZnS quantum dots. Luminescence : the journal of biological and chemical luminescence\| PubMed ID: 23681976	2013
Therapeutic peptides: new arsenal against drug resistant pathogens. Current pharmaceutical design\| PubMed ID: 23688084	2014
Assessing the amount of quadruplex structures present within G₂-tract synthetic random-sequence DNA libraries. PloS one\| PubMed ID: 23717551	2013
Exploration of structure-switching in the design of aptamer biosensors. Advances in biochemical engineering/biotechnology\| PubMed ID: 23851586	2014
Phosphorescence detection of L-ascorbic acid with surface-attached N-acetyl-L-cysteine and L-cysteine Mn doped ZnS quantum dots. Talanta\| PubMed ID: 24148476	2013
Lysozyme-stabilized gold nanoclusters as a novel fluorescence probe for cyanide recognition. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy\| PubMed ID: 24231741	2014
Evolving wonder-RNAs in a test tube. Journal of molecular evolution\| PubMed ID: 24240693	2013
Exploring intermolecular interactions of a substrate binding protein using a riboswitch-based sensor. Chemistry & biology\| PubMed ID: 24290881	2013
Construction and application of riboswitch-based sensors that detect metabolites within bacterial cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 24318895	2014
Turning tryptophanase into odor-generating biosensors. Angewandte Chemie (International ed. in English)\| PubMed ID: 24497425	2014
Artificial riboswitch selection: A FACS-based approach. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 24549612	2014
Arrest of rolling circle amplification by protein-binding DNA aptamers. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 24590539	2014
Pullulan encapsulation of labile biomolecules to give stable bioassay tablets. Angewandte Chemie (International ed. in English)\| PubMed ID: 24764260	2014
A graphene-based biosensing platform based on the release of DNA probes and rolling circle amplification. ACS nano\| PubMed ID: 24857187	2014
Engineering interlocking DNA rings with weak physical interactions. Nature communications\| PubMed ID: 24969435	2014
A sensitive DNA enzyme-based fluorescent assay for bacterial detection. Biomolecules\| PubMed ID: 24970181	2013
A general strategy to create RNA aptamer sensors using "regulated" graphene oxide adsorption. ACS applied materials & interfaces\| PubMed ID: 24992732	2014
An inkjet-printed bioactive paper sensor that reports ATP through odour generation. The Analyst\| PubMed ID: 25093215	2014
Translating bacterial detection by DNAzymes into a litmus test. Angewandte Chemie (International ed. in English)\| PubMed ID: 25213464	2014
A dual reporter system for detecting RNA interactions in bacterial cells. Chembiochem : a European journal of chemical biology\| PubMed ID: 25358737	2014
Highly specific recognition of breast tumors by an RNA-cleaving fluorogenic DNAzyme probe. Analytical chemistry\| PubMed ID: 25479319	2015
Examination of bacterial inhibition using a catalytic DNA. PloS one\| PubMed ID: 25531274	2014
Fluorescence activation imaging of cytochrome c released from mitochondria using aptameric nanosensor. Journal of the American Chemical Society\| PubMed ID: 25548948	2015
Patterned paper sensors printed with long-chain DNA aptamers. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 25820300	2015
Optimal DNA templates for rolling circle amplification revealed by in vitro selection. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 25877998	2015
An Efficient Catalytic DNA that Cleaves L-RNA. PloS one\| PubMed ID: 25946137	2015
The association of adiponectin gene promoter variations with non-small cell lung cancer in a Han Chinese population. PloS one\| PubMed ID: 26018909	2015
Evolution of an Enzyme from a Noncatalytic Nucleic Acid Sequence. Scientific reports\| PubMed ID: 26091540	2015
Biosensing by Tandem Reactions of Structure Switching, Nucleolytic Digestion, and DNA Amplification of a DNA Assembly. Angewandte Chemie (International ed. in English)\| PubMed ID: 26119600	2015
Printed paper sensors for serum lactate dehydrogenase using pullulan-based inks to immobilize reagents. Analytical chemistry\| PubMed ID: 26332017	2015
Optimized mixture of As, Cd and Pb induce mitochondria-mediated apoptosis in C6-glioma via astroglial activation, inflammation and P38-MAPK. American journal of cancer research\| PubMed ID: 26396915	2015
Sequence Mutation and Structural Alteration Transform a Noncatalytic DNA Sequence into an Efficient RNA-Cleaving DNAzyme. Journal of molecular evolution\| PubMed ID: 26530076	2015
A Quarter Century of In Vitro Selection. Journal of molecular evolution\| PubMed ID: 26597944	2015
A Catalytic DNA Activated by a Specific Strain of Bacterial Pathogen. Angewandte Chemie (International ed. in English)\| PubMed ID: 26676768	2016
Target-Induced and Equipment-Free DNA Amplification with a Simple Paper Device. Angewandte Chemie (International ed. in English)\| PubMed ID: 26748431	2016
Frozen vs Fresh Fecal Microbiota Transplantation and Clinical Resolution of Diarrhea in Patients With Recurrent Clostridium difficile Infection: A Randomized Clinical Trial. JAMA\| PubMed ID: 26757463	2016
Topological DNA Assemblies Containing Identical or Fraternal Twins. Chembiochem : a European journal of chemical biology\| PubMed ID: 26994736	2016
In vitro selection of RNA-cleaving DNAzymes for bacterial detection. Methods (San Diego, Calif.)\| PubMed ID: 27017912	2016
Programming a topologically constrained DNA nanostructure into a sensor. Nature communications\| PubMed ID: 27337657	2016