Nai-Kong V. Cheung

Department of Pediatrics, Memorial Sloan Kettering Cancer Center

Affiliated withMemorial Sloan Kettering Cancer Center

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2023

Other Publications

Article	Year
Antigen-dependent CD28 signaling selectively enhances survival and proliferation in genetically modified activated human primary T lymphocytes. The Journal of experimental medicine\| PubMed ID: 9705944	1998
Association of CYP3A4 genotype with treatment-related leukemia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 9789061	1998
Surface antigen expression and complement susceptibility of differentiated neuroblastoma clones. The American journal of pathology\| PubMed ID: 10702424	2000
Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 10706619	2000
Implications of EPHB6, EFNB2, and EFNB3 expressions in human neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 10984508	2000
Clinical categories of neuroblastoma are associated with different patterns of loss of heterozygosity on chromosome arm 1p. The Journal of molecular diagnostics : JMD\| PubMed ID: 11272900	2000
Novel regions of allelic imbalance identified by genome-wide analysis of neuroblastoma. Cancer research\| PubMed ID: 11912152	2002
Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11930009	2002
Oral (1-->3),(1-->4)-beta-D-glucan synergizes with antiganglioside GD2 monoclonal antibody 3F8 in the therapy of neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 12006541	2002
Quantitation of GD2 synthase mRNA by real-time reverse transcription-polymerase chain reaction: utility in bone marrow purging of neuroblastoma by anti-GD2 antibody 3F8. Cancer\| PubMed ID: 12115395	2002
Evolving significance of prognostic markers associated with treatment improvement in patients with stage 4 neuroblastoma. Cancer\| PubMed ID: 12173347	2002
Chronic neuroblastoma. Cancer\| PubMed ID: 12216106	2002
Disialoganglioside GD2 and a novel tumor antigen: potential targets for immunotherapy of desmoplastic small round cell tumor. Medical and pediatric oncology\| PubMed ID: 12376975	2002
Orally administered beta-glucans enhance anti-tumor effects of monoclonal antibodies. Cancer immunology, immunotherapy : CII\| PubMed ID: 12384807	2002
Anti-idiotypic antibody as the surrogate antigen for cloning scFv and its fusion proteins. Hybridoma and hybridomics\| PubMed ID: 12573107	2002
Impact of metaiodobenzylguanidine scintigraphy on assessing response of high-risk neuroblastoma to dose-intensive induction chemotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 12637474	2003
Quantitation of GD2 synthase mRNA by real-time reverse transcriptase polymerase chain reaction: clinical utility in evaluating adjuvant therapy in neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 12637475	2003
Tumor lysis syndrome, neuroblastoma, and correlation between serum lactate dehydrogenase levels and MYCN-amplification. Medical and pediatric oncology\| PubMed ID: 12764755	2003
Curability of recurrent disseminated disease after surgery alone for local-regional neuroblastoma using intensive chemotherapy and anti-G(D2) immunotherapy. Journal of pediatric hematology/oncology\| PubMed ID: 12847316	2003
Oral topotecan for refractory and relapsed neuroblastoma: a retrospective analysis. Journal of pediatric hematology/oncology\| PubMed ID: 12902911	2003
Genome-wide analysis of gene expression associated with MYCN in human neuroblastoma. Cancer research\| PubMed ID: 12907629	2003
Anti-idiotypic antibody facilitates scFv chimeric immune receptor gene transduction and clonal expansion of human lymphocytes for tumor therapy. Hybridoma and hybridomics\| PubMed ID: 14511566	2003
Early molecular response of marrow disease to biologic therapy is highly prognostic in neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 14551304	2003
Neuroblastoma in adolescents and adults: the Memorial Sloan-Kettering experience. Medical and pediatric oncology\| PubMed ID: 14595707	2003
Radically different treatment recommendations for newly diagnosed neuroblastoma: pitfalls in assessment of risk. Journal of pediatric hematology/oncology\| PubMed ID: 14707711	2004
Camptothecin analogs (irinotecan or topotecan) plus high-dose cyclophosphamide as preparative regimens for antibody-based immunotherapy in resistant neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 14734455	2004
Pharmacokinetics, dosimetry, and toxicity of the targetable atomic generator, 225Ac-HuM195, in nonhuman primates. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 14734685	2004
Treatment of spinal involvement in neuroblastoma patients. Pediatric neurosurgery\| PubMed ID: 14734862	2003
The impact of gross total resection on local control and survival in high-risk neuroblastoma. Journal of pediatric surgery\| PubMed ID: 15017562	2004
Single-chain Fv-streptavidin substantially improved therapeutic index in multistep targeting directed at disialoganglioside GD2. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 15136638	2004
Treatment reduction for neuroblastoma. Pediatric blood & cancer\| PubMed ID: 15390354	2004
Measuring circulating neuroblastoma cells by quantitative reverse transcriptase-polymerase chain reaction analysis. Cancer\| PubMed ID: 15484213	2004
Treatment of neuroblastoma meningeal carcinomatosis with intrathecal application of alpha-emitting atomic nanogenerators targeting disialo-ganglioside GD2. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15501978	2004
Reduction from seven to five cycles of intensive induction chemotherapy in children with high-risk neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 15611504	2004
Five-day courses of irinotecan as palliative therapy for patients with neuroblastoma. Cancer\| PubMed ID: 15637685	2005
Antibody-based targeted radiation to pediatric tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 15653664	2005
Long-term complications in survivors of advanced stage neuroblastoma. Pediatric blood & cancer\| PubMed ID: 15714447	2005
Characteristics of stem cells from human neuroblastoma cell lines and in tumors. Neoplasia (New York, N.Y.)\| PubMed ID: 15720811	2004
Rituximab therapy of lymphoma is enhanced by orally administered (1-->3),(1-->4)-D-beta-glucan. Leukemia research\| PubMed ID: 15863209	2005
Prognostic value of MYCN and ID2 overexpression in neuroblastoma. Pediatric blood & cancer\| PubMed ID: 16047351	2005
Liver involvement in neuroblastoma: the Memorial Sloan-Kettering Experience supports treatment reduction in young patients. Pediatric blood & cancer\| PubMed ID: 16124002	2006
Radioimmunotargeting of human rhabdomyosarcoma using monoclonal antibody 8H9. Cancer biotherapy & radiopharmaceuticals\| PubMed ID: 16248769	2005
Neuroblastoma--from genetic profiles to clinical challenge. The New England journal of medicine\| PubMed ID: 16306518	2005
High-dose cyclophosphamide inhibition of humoral immune response to murine monoclonal antibody 3F8 in neuroblastoma patients: broad implications for immunotherapy. Pediatric blood & cancer\| PubMed ID: 16421906	2007
Sialyltransferase STX (ST8SiaII): a novel molecular marker of metastatic neuroblastoma. International journal of cancer\| PubMed ID: 16450393	2006
Exploiting the MIBG-avidity of neuroblastoma for staging and treatment. Pediatric blood & cancer\| PubMed ID: 16544298	2006
FCGR2A polymorphism is correlated with clinical outcome after immunotherapy of neuroblastoma with anti-GD2 antibody and granulocyte macrophage colony-stimulating factor. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 16682723	2006
What factors predict a favorable outcome in young children with disseminated neuroblastoma? Nature clinical practice. Oncology\| PubMed ID: 16683000	2006
Ototoxicity from high-dose use of platinum compounds in patients with neuroblastoma. Cancer\| PubMed ID: 16779793	2006
Irinotecan plus temozolomide for relapsed or refractory neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 17114661	2006
Disialoganglioside directed immunotherapy of neuroblastoma. Cancer investigation\| PubMed ID: 17364560	2007
Cyclin D1, a novel molecular marker of minimal residual disease, in metastatic neuroblastoma. The Journal of molecular diagnostics : JMD\| PubMed ID: 17384216	2007
Induction for high-risk neuroblastoma. Pediatric blood & cancer\| PubMed ID: 17417798	2007
Distinct FAK-Src activation events promote alpha5beta1 and alpha4beta1 integrin-stimulated neuroblastoma cell motility. Oncogene\| PubMed ID: 17828307	2008
Brain-sparing radiotherapy for neuroblastoma skull metastases. Pediatric blood & cancer\| PubMed ID: 17973314	2008
Transient sialoadenitis: a complication of 131I-metaiodobenzylguanidine therapy. Pediatric blood & cancer\| PubMed ID: 17973318	2008
Phase I study of targeted radioimmunotherapy for leptomeningeal cancers using intra-Ommaya 131-I-3F8. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 18048828	2007
Novel markers of subclinical disease for Ewing family tumors from gene expression profiling. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 18056173	2007
Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome. Blood\| PubMed ID: 18195096	2008
Recurrent metastatic neuroblastoma followed by myelodysplastic syndrome: possible leukemogenic role of temozolomide. Pediatric blood & cancer\| PubMed ID: 18570300	2008
Solitary relapse of desmoplastic small round cell tumor detected by positron emission tomography/computed tomography. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 18809603	2008
Exploiting gene expression profiling to identify novel minimal residual disease markers of neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 18980998	2008
Management and outcome of stage 3 neuroblastoma. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 18996003	2009
Methionine depletion with recombinant methioninase: in vitro and in vivo efficacy against neuroblastoma and its synergism with chemotherapeutic drugs. International journal of cancer\| PubMed ID: 19089915	2009
Reduced risk of secondary leukemia with fewer cycles of dose-intensive induction chemotherapy in patients with neuroblastoma. Pediatric blood & cancer\| PubMed ID: 19148951	2009
Sensitivity of surveillance studies for detecting asymptomatic and unsuspected relapse of high-risk neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 19171710	2009
Specific gene expression profiles and chromosomal abnormalities are associated with infant disseminated neuroblastoma. BMC cancer\| PubMed ID: 19192278	2009
Monoclonal antibody therapies for solid tumors. Expert opinion on biological therapy\| PubMed ID: 19216623	2009
Hyperfractionated low-dose (21 Gy) radiotherapy for cranial skeletal metastases in patients with high-risk neuroblastoma. International journal of radiation oncology, biology, physics\| PubMed ID: 19427746	2009
Immunotherapy of Childhood Sarcomas. Frontiers in oncology\| PubMed ID: 26301204	2015
Analysis of GD2/GM2 synthase mRNA as a biomarker for small cell lung cancer. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 19457569	2010
MicroRNA miR-29 modulates expression of immunoinhibitory molecule B7-H3: potential implications for immune based therapy of human solid tumors. Cancer research\| PubMed ID: 19584290	2009
A focal lesion in the falx cerebri: Harbinger of classic stage 4 neuroblastoma in an infant cured despite residual disease after minimal therapy. Pediatric blood & cancer\| PubMed ID: 19711437	2009
Reducing epitope spread during affinity maturation of an anti-ganglioside GD2 antibody. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19812201	2009
Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma. Journal of neuro-oncology\| PubMed ID: 19890606	2010
KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19934297	2009
High Frequency of p53/MDM2/p14ARF Pathway Abnormalities in Relapsed Neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 20145180	2010
Whole neuraxis irradiation to address central nervous system relapse in high-risk neuroblastoma. International journal of radiation oncology, biology, physics\| PubMed ID: 20207502	2010
Neuroblastoma: Therapeutic strategies for a clinical enigma. Cancer treatment reviews\| PubMed ID: 20227189	2010
Differential impact of high-dose cyclophosphamide, topotecan, and vincristine in clinical subsets of patients with chemoresistant neuroblastoma. Cancer\| PubMed ID: 20564411	2010
Preliminary results of a phase I trial of prophylactic ethanol-lock administration to prevent mediport catheter-related bloodstream infections. Journal of pediatric surgery\| PubMed ID: 20920713	2010
High-dose cyclophosphamide-irinotecan-vincristine for primary refractory neuroblastoma. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 20934323	2011
Two-compartment model of radioimmunotherapy delivered through cerebrospinal fluid. European journal of nuclear medicine and molecular imaging\| PubMed ID: 20936407	2011
High-dose carboplatin-irinotecan-temozolomide: treatment option for neuroblastoma resistant to topotecan. Pediatric blood & cancer\| PubMed ID: 21049517	2011
Checkpoint kinase inhibitor synergizes with DNA-damaging agents in G1 checkpoint-defective neuroblastoma. International journal of cancer\| PubMed ID: 21154747	2011
Resectability and operative morbidity after chemotherapy in neuroblastoma patients with encasement of major visceral arteries. Journal of pediatric surgery\| PubMed ID: 21238649	2011
Successful multifold dose escalation of anti-GD2 monoclonal antibody 3F8 in patients with neuroblastoma: a phase I study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 21343563	2011
Plerixafor plus granulocyte-colony stimulating factor for autologous hematopoietic stem cell mobilization in patients with metastatic neuroblastoma. Pediatric blood & cancer\| PubMed ID: 21416584	2012
MYCN and MYC regulate tumor proliferation and tumorigenesis directly through BMI1 in human neuroblastomas. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 21856782	2011
Activation of peripheral-blood granulocytes is strongly correlated with patient outcome after immunotherapy with anti-GD2 monoclonal antibody and granulocyte-macrophage colony-stimulating fa... Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 22203761	2012
Association of age at diagnosis and genetic mutations in patients with neuroblastoma. JAMA\| PubMed ID: 22416102	2012
Anti-CD3â€‰Ã—â€‰anti-GD2 bispecific antibody redirects T-cell cytolytic activity to neuroblastoma targets. Pediatric blood & cancer\| PubMed ID: 22707078	2012
Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo. Oncoimmunology\| PubMed ID: 22754766	2012
Unlicensed NK cells target neuroblastoma following anti-GD2 antibody treatment. The Journal of clinical investigation\| PubMed ID: 22863621	2012
Murine anti-GD2 monoclonal antibody 3F8 combined with granulocyte-macrophage colony-stimulating factor and 13-cis-retinoic acid in high-risk patients with stage 4 neuroblastoma in first remi... Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 22869886	2012
Ifosfamide, carboplatin, and etoposide for neuroblastoma: a high-dose salvage regimen and review of the literature. Cancer\| PubMed ID: 22951749	2013
Early negative minimal residual disease in bone marrow after immunotherapy is less predictive of late or non-marrow relapse among patients with high-risk stage 4 neuroblastoma. Pediatric blood & cancer\| PubMed ID: 23335404	2013
Posterior reversible encephalopathy syndrome in neuroblastoma patients receiving anti-GD2 3F8 monoclonal antibody. Cancer\| PubMed ID: 23633099	2013
In silico driven redesign of a clinically relevant antibody for the treatment of GD2 positive tumors. PloS one\| PubMed ID: 23696816	2013
Neuroblastoma: developmental biology, cancer genomics and immunotherapy. Nature reviews. Cancer\| PubMed ID: 23702928	2013
Anti-GD2 antibody 3F8 and barley-derived (1 → 3),(1 → 4)-β-D-glucan: A Phase I study in patients with chemoresistant neuroblastoma. Oncoimmunology\| PubMed ID: 23802080	2013
Recurrent pre-existing and acquired DNA copy number alterations, including focal TERT gains, in neuroblastoma central nervous system metastases. Genes, chromosomes & cancer\| PubMed ID: 24123354	2013
Engineering anti-GD2 monoclonal antibodies for cancer immunotherapy. FEBS letters\| PubMed ID: 24295643	2014
Phase I trial of a bivalent gangliosides vaccine in combination with β-glucan for high-risk neuroblastoma in second or later remission. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 24520094	2014
Imaging the norepinephrine transporter in neuroblastoma: a comparison of [18F]-MFBG and 123I-MIBG. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 24573553	2014
Key role for myeloid cells: phase II results of anti-G(D2) antibody 3F8 plus granulocyte-macrophage colony-stimulating factor for chemoresistant osteomedullary neuroblastoma. International journal of cancer\| PubMed ID: 24644014	2014
Striking dichotomy in outcome of MYCN-amplified neuroblastoma in the contemporary era. Cancer\| PubMed ID: 24691684	2014
Structural design of disialoganglioside GD2 and CD3-bispecific antibodies to redirect T cells for tumor therapy. International journal of cancer\| PubMed ID: 24895182	2015
Deep MicroRNA sequencing reveals downregulation of miR-29a in neuroblastoma central nervous system metastasis. Genes, chromosomes & cancer\| PubMed ID: 24898736	2014
Structure Based Refinement of a Humanized Monoclonal Antibody That Targets Tumor Antigen Disialoganglioside GD2. Frontiers in immunology\| PubMed ID: 25177320	2014
Antibody induced pain in children: An opportunity to study pain mechanism, IgG design and analgesics. Pediatric blood & cancer\| PubMed ID: 25382406	2015
When overall survival fails to confirm event-free survival, should the latter be used to set the standard of care? Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 25403224	2014
GD2-targeted immunotherapy and radioimmunotherapy. Seminars in oncology\| PubMed ID: 25440605	2014
Retargeting T cells to GD2 pentasaccharide on human tumors using Bispecific humanized antibody. Cancer immunology research\| PubMed ID: 25542634	2015
Bone marrow minimal residual disease was an early response marker and a consistent independent predictor of survival after anti-GD2 immunotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 25559819	2015
Disialoganglioside GD2 as a therapeutic target for human diseases. Expert opinion on therapeutic targets\| PubMed ID: 25604432	2015
Osteochondroma in long-term survivors of high-risk neuroblastoma. Cancer\| PubMed ID: 25728463	2015
Chimeric antigen receptors and bispecific antibodies to retarget T cells in pediatric oncology. Pediatric blood & cancer\| PubMed ID: 25832831	2015
Alteration of Electrostatic Surface Potential Enhances Affinity and Tumor Killing Properties of Anti-ganglioside GD2 Monoclonal Antibody hu3F8. The Journal of biological chemistry\| PubMed ID: 25851904	2015
A dual-specific anti-IGF-1/IGF-2 human monoclonal antibody alone and in combination with temsirolimus for therapy of neuroblastoma. International journal of cancer\| PubMed ID: 25924852	2015
Low incidence of radionecrosis in children treated with conventional radiation therapy and intrathecal radioimmunotherapy. Journal of neuro-oncology\| PubMed ID: 25944385	2015
Radioimmunotherapy of human tumours. Nature reviews. Cancer\| PubMed ID: 25998714	2015
Human derived dimerization tag enhances tumor killing potency of a T-cell engaging bispecific antibody. Oncoimmunology\| PubMed ID: 26137406	2015
Prolonged progression-free survival after consolidating second or later remissions of neuroblastoma with Anti-G immunotherapy and isotretinoin: a prospective Phase II study. Oncoimmunology\| PubMed ID: 26140243	2015
A distinct gene expression signature characterizes human neuroblastoma cancer stem cells. Stem cell research\| PubMed ID: 26342562	2015
Anti-proliferative and pro-apoptotic activity of GD2 ganglioside-specific monoclonal antibody 3F8 in human melanoma cells. Oncoimmunology\| PubMed ID: 26405581	2015
Generation of TCR-Like Antibodies Using Phage Display. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 26424273	2015
Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3. The Journal of biological chemistry\| PubMed ID: 26487718	2015
Theranostic pretargeted radioimmunotherapy of colorectal cancer xenografts in mice using picomolar affinity ⁸⁶Y- or ¹⁷⁷Lu-DOTA-Bn binding scFv C825/GPA33 IgG bispecific immunoconjugates. European journal of nuclear medicine and molecular imaging\| PubMed ID: 26596724	2016
Lack of survival advantage with autologous stem-cell transplantation in high-risk neuroblastoma consolidated by anti-GD2 immunotherapy and isotretinoin. Oncotarget\| PubMed ID: 26623730	2016
Arsenic Trioxide as a Radiation Sensitizer for 131I-Metaiodobenzylguanidine Therapy: Results of a Phase II Study. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 26742708	2016
KIR3DL1 Allelic Polymorphism and HLA-B Epitopes Modulate Response to Anti-GD2 Monoclonal Antibody in Patients With Neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 27069083	2016
Antitumor Efficacy of Anti-GD2 IgG1 Is Enhanced by Fc Glyco-Engineering. Cancer immunology research\| PubMed ID: 27197064	2016
Oncotargets GD2 and GD3 are highly expressed in sarcomas of children, adolescents, and young adults. Pediatric blood & cancer\| PubMed ID: 27304202	2016
Successful engineering of a highly potent single-chain variable-fragment (scFv) bispecific antibody to target disialoganglioside (GD2) positive tumors. Oncoimmunology\| PubMed ID: 27471647	2016
Local Control With 21-Gy Radiation Therapy for High-Risk Neuroblastoma. International journal of radiation oncology, biology, physics\| PubMed ID: 27473818	2016
A phase I/Ib trial targeting the Pi3k/Akt pathway using perifosine: Long-term progression-free survival of patients with resistant neuroblastoma. International journal of cancer\| PubMed ID: 27649927	2017
Temporal stability and molecular persistence of the bone marrow plasma cell antibody repertoire. Nature communications\| PubMed ID: 28000661	2016
Combination of bevacizumab, irinotecan, and temozolomide for refractory or relapsed neuroblastoma: Results of a phase II study. Pediatric blood & cancer\| PubMed ID: 28111925	2017
Overcoming resistance to HER2-targeted therapy with a novel HER2/CD3 bispecific antibody. Oncoimmunology\| PubMed ID: 28405494	2017
Targeted drug distribution in tumor extracellular fluid of GD2-expressing neuroblastoma patient-derived xenografts using SN-38-loaded nanoparticles conjugated to the monoclonal antibody 3F8. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 28412222	2017
Immunotherapy of hepatocellular carcinoma using chimeric antigen receptors and bispecific antibodies. Cancer letters\| PubMed ID: 28428075	2017
A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors. PloS one\| PubMed ID: 28582410	2017
Limitations and opportunities for immune checkpoint inhibitors in pediatric malignancies. Cancer treatment reviews\| PubMed ID: 28622628	2017
Bispecific antibody does not induce T-cell death mediated by chimeric antigen receptor against disialoganglioside GD2. Oncoimmunology\| PubMed ID: 28680755	2017
Curative Multicycle Radioimmunotherapy Monitored by Quantitative SPECT/CT-Based Theranostics, Using Bispecific Antibody Pretargeting Strategy in Colorectal Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 28705917	2017
T cell engaging bispecific antibody (T-BsAb): From technology to therapeutics. Pharmacology & therapeutics\| PubMed ID: 28834699	2018
A phase II study of radioimmunotherapy with intraventricular I-3F8 for medulloblastoma. Pediatric blood & cancer\| PubMed ID: 28940863	2018
Erratum to 'Limitations and opportunities for immune checkpoint inhibitors in pediatric malignancies' [Cancer Treat. Rev. 58C (2017) 22-33]. Cancer treatment reviews\| PubMed ID: 29033261	2017
Targeting Intracellular Antigens with pMHC-Binding Antibodies: A Phage Display Approach. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29116509	2018
Genotyping Natural Killer Immune Checkpoints to Discover Biomarkers of Response. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 29122934	2018
Phase I trial of anti-GD2 monoclonal antibody hu3F8 plus GM-CSF: Impact of body weight, immunogenicity and anti-GD2 response on pharmacokinetics and survival. Oncoimmunology\| PubMed ID: 29147617	2017
-amplified stage 2/3 neuroblastoma: excellent survival in the era of anti-G immunotherapy. Oncotarget\| PubMed ID: 29221128	2017
Radiation Therapy to Sites of Metastatic Disease as Part of Consolidation in High-Risk Neuroblastoma: Can Long-term Control Be Achieved? International journal of radiation oncology, biology, physics\| PubMed ID: 29439882	2018
TCR-mimic bispecific antibodies targeting LMP2A show potent activity against EBV malignancies. JCI insight\| PubMed ID: 29467338	2018
Dose-escalation is needed for gross disease in high-risk neuroblastoma. Pediatric blood & cancer\| PubMed ID: 29469198	2018
Treatment and outcome of adult-onset neuroblastoma. International journal of cancer\| PubMed ID: 29574715	2018
A potent tetravalent T-cell-engaging bispecific antibody against CD33 in acute myeloid leukemia. Blood advances\| PubMed ID: 29858209	2018
Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial. The Lancet. Oncology\| PubMed ID: 29914796	2018
Development of a Tetravalent Anti-GPA33/Anti-CD3 Bispecific Antibody for Colorectal Cancers. Molecular cancer therapeutics\| PubMed ID: 30082472	2018
Adoptive immunotherapy with haploidentical natural killer cells and Anti-GD2 monoclonal antibody m3F8 for resistant neuroblastoma: Results of a phase I study. Oncoimmunology\| PubMed ID: 30221057	2018
Theranostic pretargeted radioimmunotherapy of internalizing solid tumor antigens in human tumor xenografts in mice: Curative treatment of HER2-positive breast carcinoma. Theranostics\| PubMed ID: 30429889	2018
Reduced-Dose Radiation Therapy to the Primary Site is Effective for High-Risk Neuroblastoma: Results From a Prospective Trial. International journal of radiation oncology, biology, physics\| PubMed ID: 30763661	2019
Targeted radioimmunotherapy for embryonal tumor with multilayered rosettes. Journal of neuro-oncology\| PubMed ID: 30879172	2019
Telomere Trimming and DNA Damage as Signatures of High Risk Neuroblastoma. Neoplasia (New York, N.Y.)\| PubMed ID: 31128432	2019
Exploiting Signaling Pathways and Immune Targets Beyond the Standard of Care for Ewing Sarcoma. Frontiers in oncology\| PubMed ID: 31275859	2019
Biodistribution and Dosimetry of Intraventricularly Administered I-Omburtamab in Patients with Metastatic Leptomeningeal Tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 31405921	2019
Silencing Fc Domains in T cell-Engaging Bispecific Antibodies Improves T-cell Trafficking and Antitumor Potency. Cancer immunology research\| PubMed ID: 31615814	2019
ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures. Cancer cell\| PubMed ID: 31631027	2019
An -Acetylgalactosamino Dendron-Clearing Agent for High-Therapeutic-Index DOTA-Hapten Pretargeted Radioimmunotherapy. Bioconjugate chemistry\| PubMed ID: 31891487	2020
Immunotherapy of Pediatric Solid Tumors: Treatments at a Crossroads, with an Emphasis on Antibodies. Cancer immunology research\| PubMed ID: 32015013	2020
Interdomain spacing and spatial configuration drive the potency of IgG-[L]-scFv T cell bispecific antibodies. Science translational medicine\| PubMed ID: 32161106	2020
Targets and Antibody Formats for Immunotherapy of Neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 32167865	2020
Reduced-dose craniospinal irradiation for central nervous system relapsed neuroblastoma. Pediatric blood & cancer\| PubMed ID: 32608559	2020
A Self-Assembling and Disassembling (SADA) Bispecific Antibody (BsAb) Platform for Curative Two-step Pretargeted Radioimmunotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 32958698	2021
IntraOmmaya compartmental radioimmunotherapy using I-omburtamab-pharmacokinetic modeling to optimize therapeutic index. European journal of nuclear medicine and molecular imaging\| PubMed ID: 33047248	2021
Alpha radioimmunotherapy using Ac-proteus-DOTA for solid tumors - safety at curative doses. Theranostics\| PubMed ID: 33052220	2020
Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations. Nature communications\| PubMed ID: 33056981	2020
Cancer immunotherapy via targeted TGF-β signalling blockade in T cells. Nature\| PubMed ID: 33087933	2020
B7H3-Directed Intraperitoneal Radioimmunotherapy With Radioiodinated Omburtamab for Desmoplastic Small Round Cell Tumor and Other Peritoneal Tumors: Results of a Phase I Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 33119478	2020
Overcoming leukemia heterogeneity by combining T cell engaging bispecific antibodies. Journal for immunotherapy of cancer\| PubMed ID: 33239418	2020
GD2 or HER2 targeting T cell engaging bispecific antibodies to treat osteosarcoma. Journal of hematology & oncology\| PubMed ID: 33303017	2020
Survival Impact of Anti-GD2 Antibody Response in a Phase II Ganglioside Vaccine Trial Among Patients With High-Risk Neuroblastoma With Prior Disease Progression. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 33326254	2021
Editorial: Bispecific Antibodies for T-Cell Based Immunotherapy. Frontiers in oncology\| PubMed ID: 33363043	2020
A novel multimeric IL15/IL15Rα-Fc complex to enhance cancer immunotherapy. Oncoimmunology\| PubMed ID: 33763293	2021
Engineered Cells as a Test Platform for Radiohaptens in Pretargeted Imaging and Radioimmunotherapy Applications. Bioconjugate chemistry\| PubMed ID: 33819023	2021
Potent antitumor effect of T cells armed with anti-GD2 bispecific antibody. Pediatric blood & cancer\| PubMed ID: 33844437	2021
Potent ex vivo armed T cells using recombinant bispecific antibodies for adoptive immunotherapy with reduced cytokine release. Journal for immunotherapy of cancer\| PubMed ID: 33986124	2021
T cell engaging bispecific antibodies targeting CD33 IgV and IgC domains for the treatment of acute myeloid leukemia. Journal for immunotherapy of cancer\| PubMed ID: 34035113	2021
Influence of Fc Modifications and IgG Subclass on Biodistribution of Humanized Antibodies Targeting L1CAM. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 34353869	2022
Modulating tumor infiltrating myeloid cells to enhance bispecific antibody-driven T cell infiltration and anti-tumor response. Journal of hematology & oncology\| PubMed ID: 34496935	2021
Novel potent anti-STEAP1 bispecific antibody to redirect T cells for cancer immunotherapy. Journal for immunotherapy of cancer\| PubMed ID: 34497115	2021
KMT2A-MAML2 rearrangement emerged and regressed during neuroblastoma therapy without leukemia after 12.8-year follow-up. Pediatric blood & cancer\| PubMed ID: 34550633	2022
Human Cytomegalovirus Infection Promotes Expansion of a Functionally Superior Cytoplasmic CD3 NK Cell Subset with a Bcl11b-Regulated T Cell Signature. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 34625521	2021
Intraperitoneal Pretargeted Radioimmunotherapy for Colorectal Peritoneal Carcinomatosis. Molecular cancer therapeutics\| PubMed ID: 34667111	2022
Reciprocal impacts of telomerase activity and ADRN/MES differentiation state in neuroblastoma tumor biology. Communications biology\| PubMed ID: 34799676	2021
Immunotherapy and Radioimmunotherapy for Desmoplastic Small Round Cell Tumor. Frontiers in oncology\| PubMed ID: 34869013	2021
Phase I Trial of Oral Yeast-Derived β-Glucan to Enhance Anti-GD2 Immunotherapy of Resistant High-Risk Neuroblastoma. Cancers\| PubMed ID: 34944886	2021
Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins. International journal of molecular sciences\| PubMed ID: 35008849	2021
Bone Marrow Surveillance of Pediatric Cancer Survivors Identifies Clones that Predict Therapy-Related Leukemia. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 35078859	2022
Overcoming tumor heterogeneity by ex vivo arming of T cells using multiple bispecific antibodies. Journal for immunotherapy of cancer\| PubMed ID: 35086947	2022
Bispecific antibodies for the treatment of neuroblastoma. Pharmacology & therapeutics\| PubMed ID: 35830901	2022
Immunotherapy with anti-G monoclonal antibody in infants with high-risk neuroblastoma. International journal of cancer\| PubMed ID: 35913764	2023
Connecting telomere maintenance and regulation to the developmental origin and differentiation states of neuroblastoma tumor cells. Journal of hematology & oncology\| PubMed ID: 36030273	2022
Pretargeting: A Path Forward for Radioimmunotherapy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 36215514	2022
Clinical outcomes of pediatric patients receiving multimodality treatment of second central nervous system relapse of neuroblastoma. Pediatric blood & cancer\| PubMed ID: 36349892	2023
Phase 1 study of intraventricular I-omburtamab targeting B7H3 (CD276)-expressing CNS malignancies. Journal of hematology & oncology\| PubMed ID: 36371226	2022
Desmoplastic small round cell tumor cancer stem cell-like cells resist chemotherapy but remain dependent on the EWSR1-WT1 oncoprotein. Frontiers in cell and developmental biology\| PubMed ID: 36506091	2022
Skeletal muscle metastases in neuroblastoma share common progenitors with primary tumor and biologically resemble stage MS disease. Frontiers in oncology\| PubMed ID: 36686814	2022
Targeting tumor vasculature to improve antitumor activity of T cells armed ex vivo with T cell engaging bispecific antibody. Journal for immunotherapy of cancer\| PubMed ID: 36990507	2023
Identification of immunotherapy and radioimmunotherapy targets on desmoplastic small round cell tumors. Frontiers in oncology\| PubMed ID: 37091153	2023
Clonal evolution during metastatic spread in high-risk neuroblastoma. Nature genetics\| PubMed ID: 37169874	2023