Steffen U. Eisenhardt

Department of Plastic and Hand Surgery, University of Freiburg Medical Centre

Affiliated withUniversity of Freiburg Medical Centre University of Freiburg

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 10	2012
Publication title Cited by 17	2015
Publication title Cited by 1	2025

Other Publications

Article	Year
Generation of activation-specific human anti-alphaMbeta2 single-chain antibodies as potential diagnostic tools and therapeutic agents. Blood\| PubMed ID: 17164347	2007
A mechanistic model for paradoxical platelet activation by ligand-mimetic alphaIIb beta3 (GPIIb/IIIa) antagonists. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 17170374	2007
Targeting ligand-induced binding sites on GPIIb/IIIa via single-chain antibody allows effective anticoagulation without bleeding time prolongation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 17322097	2007
Subtractive single-chain antibody (scFv) phage-display: tailoring phage-display for high specificity against function-specific conformations of cell membrane molecules. Nature protocols\| PubMed ID: 18079705	2007
Pathophysiological levels of soluble P-selectin mediate adhesion of leukocytes to the endothelium through Mac-1 activation. Circulation research\| PubMed ID: 18818407	2008
Dissociation of pentameric to monomeric C-reactive protein on activated platelets localizes inflammation to atherosclerotic plaques. Circulation research\| PubMed ID: 19520972	2009
The aging lip: a comparative histological analysis of age-related changes in the upper lip complex. Plastic and reconstructive surgery\| PubMed ID: 19644283	2009
C-reactive protein: how conformational changes influence inflammatory properties. Cell cycle (Georgetown, Tex.)\| PubMed ID: 19887916	2009
A new evaluation tool for monitoring devices and its application to evaluate the implantable Doppler probe. Journal of reconstructive microsurgery\| PubMed ID: 20143302	2010
Monomeric C-reactive protein generation on activated platelets: the missing link between inflammation and atherothrombotic risk. Trends in cardiovascular medicine\| PubMed ID: 20382347	2009
Genetic transfer of fusion proteins effectively inhibits VCAM-1-mediated cell adhesion and transmigration via inhibition of cytoskeletal anchorage. Journal of cellular and molecular medicine\| PubMed ID: 20414973	2010
An algorithm for oncologic scalp reconstruction. Plastic and reconstructive surgery\| PubMed ID: 20679829	2010
The use of the vacuum-assisted closure in microsurgical reconstruction revisited: application in the reconstruction of the posttraumatic lower extremity. Journal of reconstructive microsurgery\| PubMed ID: 20922656	2010
A proteomic analysis of C-reactive protein stimulated THP-1 monocytes. Proteome science\| PubMed ID: 21219634	2011
The diagnosis and treatment of soft tissue sarcomas of the limbs. Deutsches Ã„rzteblatt international\| PubMed ID: 21286000	2011
Retrospective analysis of 242 patients whose carpal tunnels were released using a one-port endoscopic procedure: superior results of early intervention. Journal of plastic surgery and hand surgery\| PubMed ID: 21446811	2010
Monitoring molecular changes induced by ischemia/reperfusion in human free muscle flap tissue samples. Annals of plastic surgery\| PubMed ID: 21508818	2012
Amyloid plaques dissociate pentameric to monomeric C-reactive protein: a novel pathomechanism driving cortical inflammation in Alzheimer's disease? Brain pathology (Zurich, Switzerland)\| PubMed ID: 21951392	2012
An integrated therapy concept for reduction of postoperative complications after resection of a panniculus morbidus. Obesity surgery\| PubMed ID: 22108809	2012
Ischemia-reperfusion injury leads to significant tissue damage in free flap surgery. Plastic and reconstructive surgery\| PubMed ID: 22186547	2012
Correspondence (letter to the editor): Body contouring surgery. Deutsches Ã„rzteblatt international\| PubMed ID: 22368714	2012
Technical facilitation of the fleur-de-lis abdominoplasty for symmetrical resection patterns in massive weight loss patients. Plastic and reconstructive surgery\| PubMed ID: 22374036	2012
Circulating microparticles generate and transport monomeric C-reactive protein in patients with myocardial infarction. Cardiovascular research\| PubMed ID: 22798388	2012
Pentameric CRP attenuates inflammatory effects of mmLDL by inhibiting mmLDL--monocyte interactions. Atherosclerosis\| PubMed ID: 22901456	2012
MicroRNAs in ischemia-reperfusion injury. American journal of cardiovascular disease\| PubMed ID: 22937493	2012
Invited commentary. Journal of plastic, reconstructive & aesthetic surgery : JPRAS\| PubMed ID: 21795131	2011
Negative pressure wound therapy reduces the ischaemia/reperfusion-associated inflammatory response in free muscle flaps. Journal of plastic, reconstructive & aesthetic surgery : JPRAS\| PubMed ID: 22137686	2012
A conformational change of C-reactive protein in burn wounds unmasks its proinflammatory properties. International immunology\| PubMed ID: 24844702	2014
Dissociation of pentameric to monomeric C-reactive protein localizes and aggravates inflammation: in vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy. Circulation\| PubMed ID: 24982116	2014
Salvage procedures after failed facial reanimation surgery using the masseteric nerve as the motor nerve for free functional gracilis muscle transfer. JAMA facial plastic surgery\| PubMed ID: 24994013	2014
Comment on "Lengthening temporalis myoplasty and congenital facial paralysis". Journal of plastic, reconstructive & aesthetic surgery : JPRAS\| PubMed ID: 25661799	2015
MicroRNA-155 aggravates ischemia-reperfusion injury by modulation of inflammatory cell recruitment and the respiratory oxidative burst. Basic research in cardiology\| PubMed ID: 25916938	2015
Identification of a blood-borne miRNA signature of synovial sarcoma. Molecular cancer\| PubMed ID: 26250552	2015
Microsurgical reconstruction of oncological scalp defects in the elderly. Journal of plastic, reconstructive & aesthetic surgery : JPRAS\| PubMed ID: 27133193	2016
Metabolic Response to XD14 Treatment in Human Breast Cancer Cell Line MCF-7. International journal of molecular sciences\| PubMed ID: 27783056	2016
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites. Nature communications\| PubMed ID: 28112148	2017
Analysis of the ideal muscle weight of gracilis muscle transplants for facial reanimation surgery with regard to the donor nerve and outcome. Journal of plastic, reconstructive & aesthetic surgery : JPRAS\| PubMed ID: 28159544	2017
Levels of activated platelet-derived microvesicles in patients with soft tissue sarcoma correlate with an increased risk of venous thromboembolism. BMC cancer\| PubMed ID: 28784104	2017
Pedicled and free flaps for intrathoracic fistula management. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 29106507	2017
Evaluation of the Implantable Doppler Probe for Free Flap Monitoring in Lower Limb Reconstruction. Journal of reconstructive microsurgery\| PubMed ID: 29179224	2018
Comparison of symmetry after smile reconstruction for flaccid facial paralysis with combined fascia lata grafts and functional gracilis transfer for static suspension or gracilis transfer al... Microsurgery\| PubMed ID: 29603352	2018
Extracellular Vesicles: Packages Sent With Complement. Frontiers in immunology\| PubMed ID: 29696020	2018
A Conformational Change in C-Reactive Protein Enhances Leukocyte Recruitment and Reactive Oxygen Species Generation in Ischemia/Reperfusion Injury. Frontiers in immunology\| PubMed ID: 29713320	2018
Dissociation of C-Reactive Protein Localizes and Amplifies Inflammation: Evidence for a Direct Biological Role of C-Reactive Protein and Its Conformational Changes. Frontiers in immunology\| PubMed ID: 29946323	2018
Pre-operative masseter muscle EMG activation during smile predicts synchronicity of smile development in facial palsy patients undergoing reanimation with the masseter nerve: A prospective c... Journal of plastic, reconstructive & aesthetic surgery : JPRAS\| PubMed ID: 30509736	2019
Genotyping of circulating cell-free DNA enables noninvasive tumor detection in myxoid liposarcomas. International journal of cancer\| PubMed ID: 30779112	2019
Lysophosphatidylcholine is a Major Component of Platelet Microvesicles Promoting Platelet Activation and Reporting Atherosclerotic Plaque Instability. Thrombosis and haemostasis\| PubMed ID: 31378855	2019
Retrospective evaluation of diagnostic accuracy of free flap monitoring with the Cook-Swartz-Doppler probe in head and neck reconstruction. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery\| PubMed ID: 31810844	2019
Efficacy and Safety of Microsurgery in Interdisciplinary Treatment of Sarcoma Affecting the Bone. Frontiers in oncology\| PubMed ID: 31850204	2019
Combination of Static and Dynamic Techniques for Smile Reconstruction in Patients with Flaccid Facial Paralysis. Plastic and reconstructive surgery. Global open\| PubMed ID: 31942352	2019
C-Reactive Protein and Its Structural Isoforms: An Evolutionary Conserved Marker and Central Player in Inflammatory Diseases and Beyond. Sub-cellular biochemistry\| PubMed ID: 32189313	2020
Reconstruction of Perineal Defects: A Comparison of the Myocutaneous Gracilis and the Gluteal Fold Flap in Interdisciplinary Anorectal Tumor Resection. Frontiers in oncology\| PubMed ID: 32435617	2020
An Unbiased Flow Cytometry-Based Approach to Assess Subset-Specific Circulating Monocyte Activation and Cytokine Profile in Whole Blood. Frontiers in immunology\| PubMed ID: 33981302	2021
Artificial Intelligence-Driven Video Analysis for Novel Outcome Measures After Smile Reanimation Surgery. Facial plastic surgery & aesthetic medicine\| PubMed ID: 34166082	2022
Genetic Deficiency of TRAF5 Promotes Adipose Tissue Inflammation and Aggravates Diet-Induced Obesity in Mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 34348490	2021
CRP Enhances the Innate Killing Mechanisms Phagocytosis and ROS Formation in a Conformation and Complement-Dependent Manner. Frontiers in immunology\| PubMed ID: 34447388	2021
PY receptor blockers are anti-inflammatory drugs inhibiting both circulating monocytes and macrophages including THP-1 cells. Scientific reports\| PubMed ID: 34465804	2021
Pharmacokinetic study of the novel phosphocholine derivative 3-dibutylaminopropylphosphonic acid by LC-MS coupling. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 34798417	2021
Transitional changes in the structure of C-reactive protein create highly pro-inflammatory molecules: Therapeutic implications for cardiovascular diseases. Pharmacology & therapeutics\| PubMed ID: 35247517	2022
Genotyping of Circulating Free DNA Enables Monitoring of Tumor Dynamics in Synovial Sarcomas. Cancers\| PubMed ID: 35565213	2022
Age-related outcome of facial reanimation surgery using cross face nerve graft and gracilis free functional muscle transfer-A retrospective cohort study. Microsurgery\| PubMed ID: 35579294	2022
Oncological Safety and Recurrence in the Surgical Treatment of Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma of the Scalp. Cancers\| PubMed ID: 35740535	2022
Autologous free tissue transfer in paediatric patient with a univentricular heart. Interactive cardiovascular and thoracic surgery\| PubMed ID: 35792870	2022
An Analysis of the Implantable Doppler Probe for Postoperative Free-Flap Monitoring and Risk Factor Analysis for Revision Surgery in Facial Reanimation Surgery. Facial plastic surgery & aesthetic medicine\| PubMed ID: 35998234	2022
Individualized Mini-Panel Sequencing of ctDNA Allows Tumor Monitoring in Complex Karyotype Sarcomas. International journal of molecular sciences\| PubMed ID: 36142126	2022
C-reactive protein, immunothrombosis and venous thromboembolism. Frontiers in immunology\| PubMed ID: 36177015	2022
A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein. EMBO molecular medicine\| PubMed ID: 36468184	2023
Newly identified axon types of the facial nerve unveil supplemental neural pathways in the innervation of the face. Journal of advanced research\| PubMed ID: 36725185	2023
Dermatofibrosarcoma protuberans of the scalp: Surgical management in a multicentric series of 11 cases and systematic review of the literature. Surgery\| PubMed ID: 37012145	2023
Multiparametric magnetic resonance imaging for radiation therapy response monitoring in soft tissue sarcomas: a histology and MRI co-registration algorithm. Theranostics\| PubMed ID: 37056570	2023
Correlation between facial vascularized composite allotransplantation rejection and laboratory markers: Insights from a retrospective study of eight patients. Journal of plastic, reconstructive & aesthetic surgery : JPRAS\| PubMed ID: 37276734	2023
Functional Outcome of Dual Reinnervation with Cross-Facial Nerve Graft and Masseteric Nerve Transfer for Facial Paralysis. Plastic and reconstructive surgery\| PubMed ID: 37384874	2024
Age-related outcomes of facial reanimation surgery using gracilis free functional muscle transfer innervated by the masseteric nerve: A retrospective cohort study. Journal of plastic, reconstructive & aesthetic surgery : JPRAS\| PubMed ID: 37586310	2023
Intravital Imaging of Leukocyte-Endothelial Interaction in Hindlimb Ischemia/Reperfusion Injury by Intravital Multiphoton Microscopy. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 37776451	2024
Special Issue: Evidence-Based Diagnosis and Management of Facial Nerve Disorders. Diagnostics (Basel, Switzerland)\| PubMed ID: 37835799	2023
Non-invasive monitoring of neoadjuvant radiation therapy response in soft tissue sarcomas by multiparametric MRI and quantification of circulating tumor DNA-A study protocol. PloS one\| PubMed ID: 37910565	2023
Secondary dynamic midface reanimation with gracilis free muscle transfer after failed reconstruction attempt: A 15-year experience. Journal of plastic, reconstructive & aesthetic surgery : JPRAS\| PubMed ID: 37925922	2023
C-reactive protein orchestrates acute allograft rejection in vascularized composite allotransplantation via selective activation of monocyte subsets. Journal of advanced research\| PubMed ID: 38992424	2024
Shear-Sensing by C-Reactive Protein: Linking Aortic Stenosis and Inflammation. Circulation research\| PubMed ID: 39421928	2024
Antithrombotic Agents after Free Tissue Transfer in the Pediatric and Adolescent Population. Journal of reconstructive microsurgery\| PubMed ID: 39496320	2024
A conformational change of C-reactive protein drives neutrophil extracellular trap formation in inflammation. BMC biology\| PubMed ID: 39773175	2025
Microsurgical versus complex physical decongestive therapy for chronic breast cancer-related lymphoedema. The Cochrane database of systematic reviews\| PubMed ID: 39945379	2025
Artificial Intelligence in Facial Palsy Treatment: A Systematic Review and Recommendations. Plastic and reconstructive surgery\| PubMed ID: 40099668	2025