Dennis K. Ninaber

PulmoScience Laboratory, Leiden University Medical Center

Affiliated withLeiden University Medical Center

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 25	2023

Other Publications

Article	Year
Host defense effector molecules in mucosal secretions. FEMS immunology and medical microbiology\| PubMed ID: 16051067	2005
Human cathelicidin LL-37 is a chemoattractant for eosinophils and neutrophils that acts via formyl-peptide receptors. International archives of allergy and immunology\| PubMed ID: 16557028	2006
The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14662872	2003
Epithelial differentiation is a determinant in the production of eotaxin-2 and -3 by bronchial epithelial cells in response to IL-4 and IL-13. Molecular immunology\| PubMed ID: 16740309	2007
The antimicrobial peptide LL-37 enhances IL-8 release by human airway smooth muscle cells. The Journal of allergy and clinical immunology\| PubMed ID: 16750994	2006
IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides. Respiratory research\| PubMed ID: 21529380	2011
Arterivirus and nairovirus ovarian tumor domain-containing Deubiquitinases target activated RIG-I to control innate immune signaling. Journal of virology\| PubMed ID: 22072774	2012
Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23401522	2013
Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demon... The Journal of biological chemistry\| PubMed ID: 25320088	2014
Metabolic Engineering toward Sustainable Production of Nylon-6. ACS synthetic biology\| PubMed ID: 26511532	2016
Proinflammatory Cytokines Impair Vitamin D-Induced Host Defense in Cultured Airway Epithelial Cells. American journal of respiratory cell and molecular biology\| PubMed ID: 28231019	2017
Cigarette smoke differentially affects IL-13-induced gene expression in human airway epithelial cells. Physiological reports\| PubMed ID: 28701525	2017
Effect of diesel exhaust generated by a city bus engine on stress responses and innate immunity in primary bronchial epithelial cell cultures. Toxicology in vitro : an international journal published in association with BIBRA\| PubMed ID: 29408669	2018
Farm dust reduces viral load in human bronchial epithelial cells by increasing barrier function and antiviral responses. The Journal of allergy and clinical immunology\| PubMed ID: 29425849	2018
Aberrant epithelial differentiation by cigarette smoke dysregulates respiratory host defence. The European respiratory journal\| PubMed ID: 29545277	2018
TGF-β1 Impairs Vitamin D-Induced and Constitutive Airway Epithelial Host Defense Mechanisms. Journal of innate immunity\| PubMed ID: 30970352	2020
In vitro modelling of alveolar repair at the air-liquid interface using alveolar epithelial cells derived from human induced pluripotent stem cells. Scientific reports\| PubMed ID: 32218519	2020
Suramin Inhibits SARS-CoV-2 Infection in Cell Culture by Interfering with Early Steps of the Replication Cycle. Antimicrobial agents and chemotherapy\| PubMed ID: 32513797	2020
Tiotropium and Fluticasone Inhibit Rhinovirus-Induced Mucin Production via Multiple Mechanisms in Differentiated Airway Epithelial Cells. Frontiers in cellular and infection microbiology\| PubMed ID: 32637364	2020
Disease modeling following organoid-based expansion of airway epithelial cells. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 34378410	2021
Dysregulated mitochondrial metabolism upon cigarette smoke exposure in various human bronchial epithelial cell models. Disease models & mechanisms\| PubMed ID: 35344036	2022
Early transcriptional responses of bronchial epithelial cells to whole cigarette smoke mirror those of in-vivo exposed human bronchial mucosa. Respiratory research\| PubMed ID: 36056356	2022
Cigarette Smoke Impairs Airway Epithelial Wound Repair: Role of Modulation of Epithelial-Mesenchymal Transition Processes and Notch-1 Signaling. Antioxidants (Basel, Switzerland)\| PubMed ID: 36290742	2022
R-Propranolol Has Broad-Spectrum Anti-Coronavirus Activity and Suppresses Factors Involved in Pathogenic Angiogenesis. International journal of molecular sciences\| PubMed ID: 36902020	2023