D.A. Lydall

Institute for Cell and Molecular Biosciences, Newcastle University Medical School

Affiliated withNewcastle University Medical School

Research Area

Biography

D.A. Lydall has not added Biography.
If you are D.A. Lydall and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 25	2012

Other Publications

Article	Year
The Walker 256 carcinoma: a cell type inherently sensitive only to those difunctional agents that can form DNA interstrand crosslinks. Mutation research\| PubMed ID: 1719394	1991
A new role for MCM1 in yeast: cell cycle regulation of SW15 transcription. Genes & development\| PubMed ID: 1752436	1991
Changes in a SWI4,6-DNA-binding complex occur at the time of HO gene activation in yeast. Genes & development\| PubMed ID: 1936990	1991
The identification of a second cell cycle control on the HO promoter in yeast: cell cycle regulation of SW15 nuclear entry. Cell\| PubMed ID: 2167175	1990
Mechanism of cytotoxicity of anticancer platinum drugs: evidence that cis-diamminedichloroplatinum(II) and cis-diammine-(1,1-cyclobutanedicarboxylato)platinum(II) differ only in the kinetics... Cancer research\| PubMed ID: 3512077	1986
The effect of monofunctional or difunctional platinum adducts and of various other associated DNA damage on the expression of transfected DNA in mammalian cell lines sensitive or resistant t... Biochimica et biophysica acta\| PubMed ID: 3567197	1987
Yeast checkpoint genes in DNA damage processing: implications for repair and arrest. Science (New York, N.Y.)\| PubMed ID: 7491494	1995
Cell cycle checkpoints, genetic instability and cancer. Seminars in cancer biology\| PubMed ID: 8513148	1993
From DNA damage to cell cycle arrest and suicide: a budding yeast perspective. Current opinion in genetics & development\| PubMed ID: 8791492	1996
A meiotic recombination checkpoint controlled by mitotic checkpoint genes. Nature\| PubMed ID: 8893012	1996
Use of cdc13-1-induced DNA damage to study effects of checkpoint genes on DNA damage processing. Methods in enzymology\| PubMed ID: 9251038	1997
G2/M checkpoint genes of Saccharomyces cerevisiae: further evidence for roles in DNA replication and/or repair. Molecular & general genetics : MGG\| PubMed ID: 9435789	1997
NDD1, a high-dosage suppressor of cdc28-1N, is essential for expression of a subset of late-S-phase-specific genes in Saccharomyces cerevisiae. Molecular and cellular biology\| PubMed ID: 10207056	1999
Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction. Nucleic acids research\| PubMed ID: 11691929	2001
EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants. Genes & development\| PubMed ID: 12154123	2002
Hiding at the ends of yeast chromosomes: telomeres, nucleases and checkpoint pathways. Journal of cell science\| PubMed ID: 12972499	2003
A domain of Rad9 specifically required for activation of Chk1 in budding yeast. Journal of cell science\| PubMed ID: 14709724	2004
Mec1 and Rad53 inhibit formation of single-stranded DNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants. Genetics\| PubMed ID: 15020465	2004
EXO1 plays a role in generating type I and type II survivors in budding yeast. Genetics\| PubMed ID: 15126386	2004
Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants. Genetics\| PubMed ID: 15454530	2004
Telomerase- and recombination-independent immortalization of budding yeast. Genes & development\| PubMed ID: 15489288	2004
The PAL-mechanism of chromosome maintenance: causes and consequences. Cell cycle (Georgetown, Tex.)\| PubMed ID: 15970690	2005
Chromatin and the DNA damage response. DNA repair\| PubMed ID: 16046284	2005
Pulsed-field gel electrophoresis of budding yeast chromosomes. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 16118425	2006
A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator. Cell\| PubMed ID: 16564010	2006
Positional cloning of a cyromazine resistance gene in Drosophila melanogaster. Insect molecular biology\| PubMed ID: 16640728	2006
MRX protects telomeric DNA at uncapped telomeres of budding yeast cdc13-1 mutants. DNA repair\| PubMed ID: 16765654	2006
Linear chromosome maintenance in the absence of essential telomere-capping proteins. Nature cell biology\| PubMed ID: 16767084	2006
Detecting repair intermediates in vivo: effects of DNA damage response genes on single-stranded DNA accumulation at uncapped telomeres in budding yeast. Methods in enzymology\| PubMed ID: 16793407	2006
Modelling the checkpoint response to telomere uncapping in budding yeast. Journal of the Royal Society, Interface / the Royal Society\| PubMed ID: 17015293	2007
MTAS: Mental health of applicants seems to be deteriorating. BMJ (Clinical research ed.)\| PubMed ID: 17599984	2007
Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1. DNA repair\| PubMed ID: 17618841	2007
Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres. The EMBO journal\| PubMed ID: 18418382	2008
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response. The EMBO journal\| PubMed ID: 18756267	2008
A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection. Genome biology\| PubMed ID: 18828915	2008
A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae. Genetics\| PubMed ID: 18845848	2008
Psychological impact of systemic training failure on mental health and career satisfaction of UK trainees: lessons from an online attitudes survey. The International journal of social psychiatry\| PubMed ID: 19240207	2009
Telomere maintenance and survival in saccharomyces cerevisiae in the absence of telomerase and RAD52. Genetics\| PubMed ID: 19380905	2009
Taming the tiger by the tail: modulation of DNA damage responses by telomeres. The EMBO journal\| PubMed ID: 19629039	2009
Support of association between BRD1 and both schizophrenia and bipolar affective disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics\| PubMed ID: 19693800	2010
Analysis of licking microstructure provides no evidence for a reduction in reward value following acute or sub-chronic phencyclidine administration. Psychopharmacology\| PubMed ID: 20145910	2010
Colonyzer: automated quantification of micro-organism growth characteristics on solid agar. BMC bioinformatics\| PubMed ID: 20509870	2010
Telomere replication: Mre11 leads the way. Molecular cell\| PubMed ID: 20620949	2010
Survival and growth of yeast without telomere capping by Cdc13 in the absence of Sgs1, Exo1, and Rad9. PLoS genetics\| PubMed ID: 20808892	2010
Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping. The EMBO journal\| PubMed ID: 21045806	2010
Analysis of genetic deletions and duplications in the University College London bipolar disorder case control sample. European journal of human genetics : EJHG\| PubMed ID: 21206513	2011
Simultaneous contrast: evidence from licking microstructure and cross-solution comparisons. Journal of experimental psychology. Animal behavior processes\| PubMed ID: 21381860	2011
Lack of allelic association between markers at the DRD2 and ANKK1 gene loci with the alcohol-dependence syndrome and criminal activity. Psychiatric genetics\| PubMed ID: 21403585	2011
Customizable views on semantically integrated networks for systems biology. Bioinformatics (Oxford, England)\| PubMed ID: 21414991	2011
Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects. PLoS genetics\| PubMed ID: 21490951	2011
Genetic association study of GABRA2 single nucleotide polymorphisms and electroencephalography in alcohol dependence. Neuroscience letters\| PubMed ID: 21683760	2011
Confirmation of prior evidence of genetic susceptibility to alcoholism in a genome-wide association study of comorbid alcoholism and bipolar disorder. Psychiatric genetics\| PubMed ID: 21876473	2011
Similarities and differences between "uncapped" telomeres and DNA double-strand breaks. Chromosoma\| PubMed ID: 22203190	2012
Genome-wide analysis to identify pathways affecting telomere-initiated senescence in budding yeast. G3 (Bethesda, Md.)\| PubMed ID: 22384331	2011
Choice of antipsychotic treatment by European psychiatry trainees: are decisions based on evidence? BMC psychiatry\| PubMed ID: 22463055	2012