Kristina W. Thiel

Department of Obstetrics and Gynecology, University of Iowa

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2024

Other Publications

Article	Year
Effects of bevacizumab in mouse model of endometrial cancer: Defining the molecular basis for resistance. Oncology reports\| PubMed ID: 21240464	2011
Therapeutic applications of DNA and RNA aptamers. Oligonucleotides\| PubMed ID: 19653880	2009
Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors. Nature biotechnology\| PubMed ID: 19701187	2009
Progesterone: the ultimate endometrial tumor suppressor. Trends in endocrinology and metabolism: TEM\| PubMed ID: 21353793	2011
Knockdown of MTDH sensitizes endometrial cancer cells to cell death induction by death receptor ligand TRAIL and HDAC inhibitor LBH589 co-treatment. PloS one\| PubMed ID: 21687633	2011
Endometrial cancer: reviving progesterone therapy in the molecular age. Discovery medicine\| PubMed ID: 21955848	2011
Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers. Nucleic acids research\| PubMed ID: 22467215	2012
Endometrial cancer. Obstetrics and gynecology clinics of North America\| PubMed ID: 22640714	2012
An exploratory study of the variables impacting preterm birth rates in New Mexico. BMC pregnancy and childbirth\| PubMed ID: 22720802	2012
Catch it before it kills: progesterone, obesity, and the prevention of endometrial cancer. Discovery medicine\| PubMed ID: 23021376	2012
Epigenetic modification restores functional PR expression in endometrial cancer cells. Current pharmaceutical design\| PubMed ID: 23888956	2014
Drug resistance mediated by AEG-1/MTDH/LYRIC. Advances in cancer research\| PubMed ID: 23889990	2013
The consequence of oncomorphic TP53 mutations in ovarian cancer. International journal of molecular sciences\| PubMed ID: 24065105	2013
The epidermal growth factor receptor and its ligands in cardiovascular disease. International journal of molecular sciences\| PubMed ID: 24132149	2013
The estrogen receptor joins other cancer biomarkers as a predictor of outcome. Obstetrics and gynecology international\| PubMed ID: 24223042	2013
Strategies for Molecularly Enhanced Chemotherapy to Achieve Synthetic Lethality in Endometrial Tumors with Mutant p53. Obstetrics and gynecology international\| PubMed ID: 24381593	2013
Comprehensive profiling of EGFR/HER receptors for personalized treatment of gynecologic cancers. Molecular diagnosis & therapy\| PubMed ID: 24403167	2014
Past, present, and future of hormonal therapy in recurrent endometrial cancer. International journal of women's health\| PubMed ID: 24833920	2014
Systematic dissection of the mechanisms underlying progesterone receptor downregulation in endometrial cancer. Oncotarget\| PubMed ID: 25229191	2014
Cell-internalization SELEX: method for identifying cell-internalizing RNA aptamers for delivering siRNAs to target cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25319652	2015
TP53 oncomorphic mutations predict resistance to platinum‑ and taxane‑based standard chemotherapy in patients diagnosed with advanced serous ovarian carcinoma. International journal of oncology\| PubMed ID: 25385265	2015
Genetic Deficiency of Mtdh Gene in Mice Causes Male Infertility via Impaired Spermatogenesis and Alterations in the Expression of Small Non-coding RNAs. The Journal of biological chemistry\| PubMed ID: 25787082	2015
miR-888: A Novel Cancer-Testis Antigen that Targets the Progesterone Receptor in Endometrial Cancer. Translational oncology\| PubMed ID: 25926074	2015
NEDD4 ubiquitin ligase is a putative oncogene in endometrial cancer that activates IGF-1R/PI3K/Akt signaling. Gynecologic oncology\| PubMed ID: 26193427	2015
Downregulation of FOXO1 mRNA levels predicts treatment failure in patients with endometrial pathology conservatively managed with progestin-containing intrauterine devices. Gynecologic oncology\| PubMed ID: 26524723	2016
Inverse Relationship between Progesterone Receptor and Myc in Endometrial Cancer. PloS one\| PubMed ID: 26859414	2016
Stratification of endometrioid endometrial cancer patients into risk levels using somatic mutations. Gynecologic oncology\| PubMed ID: 27181389	2016
Prediction of chemo-response in serous ovarian cancer. Molecular cancer\| PubMed ID: 27756408	2016
Placenta-Specific Protein 1 Expression in Human Papillomavirus 16/18-Positive Cervical Cancers Is Associated With Tumor Histology. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society\| PubMed ID: 28375929	2017
High stathmin expression is a marker for poor clinical outcome in endometrial cancer: An NRG oncology group/gynecologic oncology group study. Gynecologic oncology\| PubMed ID: 28532857	2017
Role of metadherin in estrogen-regulated gene expression. International journal of molecular medicine\| PubMed ID: 28627585	2017
Synthetically lethal nanoparticles for treatment of endometrial cancer. Nature nanotechnology\| PubMed ID: 29203914	2018
AZD1775 Increases Sensitivity to Olaparib and Gemcitabine in Cancer Cells with p53 Mutations. Cancers\| PubMed ID: 29783721	2018
Combination of Proteasome and Histone Deacetylase Inhibitors Overcomes the Impact of Gain-of-Function p53 Mutations. Disease markers\| PubMed ID: 30647797	2018
A Prediction Model for Preoperative Risk Assessment in Endometrial Cancer Utilizing Clinical and Molecular Variables. International journal of molecular sciences\| PubMed ID: 30857319	2019
Molecular Characterization of Non-responders to Chemotherapy in Serous Ovarian Cancer. International journal of molecular sciences\| PubMed ID: 30866519	2019
An integrated prediction model of recurrence in endometrial endometrioid cancers. Cancer management and research\| PubMed ID: 31239780	2019
MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy. Gynecologic oncology\| PubMed ID: 31477281	2019
Characterization of a TP53 Somatic Variant of Unknown Function From an Ovarian Cancer Patient Using Organoid Culture and Computational Modeling. Clinical obstetrics and gynecology\| PubMed ID: 31876640	2020
Loss of progesterone receptor through epigenetic regulation is associated with poor prognosis in solid tumors. American journal of cancer research\| PubMed ID: 32642294	2020
The Dawning of the Age of Personalized Medicine in Gynecologic Oncology. Cancers\| PubMed ID: 33120871	2020
Genomic characterization of five commonly used endometrial cancer cell lines. International journal of oncology\| PubMed ID: 33174010	2020
Mutated p53 portends improvement in outcomes when bevacizumab is combined with chemotherapy in advanced/recurrent endometrial cancer: An NRG Oncology study. Gynecologic oncology\| PubMed ID: 33541735	2021
Creation and validation of models to predict response to primary treatment in serous ovarian cancer. Scientific reports\| PubMed ID: 33727600	2021
Bacterial, Archaea, and Viral Transcripts (BAVT) Expression in Gynecological Cancers and Correlation with Regulatory Regions of the Genome. Cancers\| PubMed ID: 33807612	2021
Targeting Wnt Signaling in Endometrial Cancer. Cancers\| PubMed ID: 34068065	2021
Successful Patient-Derived Organoid Culture of Gynecologic Cancers for Disease Modeling and Drug Sensitivity Testing. Cancers\| PubMed ID: 34200645	2021
Advantages of Tyrosine Kinase Anti-Angiogenic Cediranib over Bevacizumab: Cell Cycle Abrogation and Synergy with Chemotherapy. Pharmaceuticals (Basel, Switzerland)\| PubMed ID: 34358108	2021
Blocking autophagy overcomes resistance to dual histone deacetylase and proteasome inhibition in gynecologic cancer. Cell death & disease\| PubMed ID: 35039480	2022
Sequencing and p53 Immunohistochemistry Predict Outcomes When Bevacizumab Is Added to Frontline Chemotherapy in Endometrial Cancer: An NRG Oncology/Gynecologic Oncology Group Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 35658479	2022
Characterization of HCI-EC-23 a novel estrogen- and progesterone-responsive endometrial cancer cell line. Scientific reports\| PubMed ID: 36396974	2022
Global expression analysis of endometrial cancer cells in response to progesterone identifies new therapeutic targets. The Journal of steroid biochemistry and molecular biology\| PubMed ID: 37716459	2023
Multiplexed live-cell imaging for drug responses in patient-derived organoid models of cancer. bioRxiv : the preprint server for biology\| PubMed ID: 38014133	2023
AptamerRunner: An accessible aptamer structure prediction and clustering algorithm for visualization of selected aptamers. bioRxiv : the preprint server for biology\| PubMed ID: 38014343	2023